Baylor College of Medicine News

Duncan Cancer Center researchers awarded $13 million in new round of CPRIT grants

 Researchers in the NCI-designated Dan L. Duncan Cancer Center at Baylor College of Medicine have received an additional $13 million in the new round of grants announced by the Cancer Prevention Research Institute of Texas Wednesday.

The Duncan Cancer Center has received more than $60 million in CPRIT funding since the institute began awarding cancer grants to Texas researchers in January 2010.

"These research grants are especially important considering the marked reduction in research funding for cancer and other diseases from the federal government," said Dr. Kent Osborne, director of the Duncan Cancer Center.

New awards include:

-Award to recruit Dr. Daisuke Nakada, a promising young scientist from the University of Michigan. A stem cell biologist, Nakada's research focuses on how stem cell maintenance and tumorigenesis are controlled by mechanisms that regulate chromosome stability and energy metabolism ($2 million award).

-Dr. Dean Edwards, professor of molecular and cellular biology, to establish a proteomics and metabolomics core facility ($6 million award).

-Dr. Kenneth Scott, assistant professor of molecular and human genetics, to study functional genomics approaches for screening mutation drivers of pancreatic ductal adenocarcinoma ($803,179 award).

-Dr. Alison Bertuch, assistant professor of molecular and human genetics, and of pediatrics-hematology and oncology, and a member of the Texas Children's Cancer Center, to study novel mechanisms leading to telomere dysfunction and cancer predisposition ($937,896 award).

-Dr. David Moore, professor of molecular and human genetics and of molecular and cellular biology, and a member of the USDA/ARS Children's Nutrition Research Center at BCM and Texas Children's Hospital, to study nuclear receptors and Hippo signaling in liver cancer ($1,214,977 award).

-Dr. Barbara Savoldo, a professor of pediatrics – hematology and oncology, a member of the Texas Children's Cancer Center and the Center for Cell and Gene Therapy at BCM, Texas Children's and The Methodist Hospital, to study chimeric T –cells for therapy of Hodgkin Lymphomas and the CD30+ Non Hodgkin Lymphomas ($905,975 award).

-Dr. Thomas Westbrook, professor of biochemistry and molecular biology, molecular and human genetics, and pediatrics, to study a new functional genomics approach to discovering therapeutic targets for breast cancer ($1,102,029 award).