Researchers at Baylor College of Medicine are seeking clinical trial volunteers for new Alzheimer’s disease prevention and treatment studies, and even if you haven’t been diagnosed with Alzheimer’s, you can still be a part of the work to understand this debilitating disease and find a cure.

“There are still unknowns about this disease and continued research is needed, not just involving those who are living with the disease but also those who are a part of the healthy elderly population,” said Dr. Valory Pavlik, associate professor of neurology and associate director of the Alzheimer’s Disease and Memory Disorders Center at Baylor. “Researchers have learned that Alzheimer’s treatment may need to start even before any symptoms appear.” 

A new study, called Generation2, is testing a treatment taken in pill form that prevents the buildup of amyloid protein in the brain in cognitively healthy people age 60 and above. This protein is thought to trigger the onset of Alzheimer’s disease, and researchers hope that the study medicine will stop this process.

The Alzheimer’s Center continues to focus on finding more effective treatments for those who are already dealing with memory problems.  

“We have had some disappointing trial results recently, but even when a trial is not successful it shows us what other areas we should be focusing on instead,” said Dr. Joseph Kass, director of the Alzheimer’s Center and professor of neurology, psychiatry and behavioral sciences and medical ethics and health policy at Baylor. “There are some very promising treatments in the late-testing phase, meaning they are closer to public use than early-phase trials, and we are recruiting for those as well.”

Some of those trials include evaluating medications to reduce symptoms of agitation and which imaging test might be used to best assess mild cognitive impairment and progression.

To learn more about these and other opportunities as well as eligibility, contact alzheimers-research@bcm.edu or (713) 798-5328.