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Houseweart MK, Pennacchio LA, Vilaythong A, Peters C, Noebels JL, Myers RM. Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). J Neurobiol. 2003;56(4):315-27. PMID: 12918016.

56

Houseweart MK, Vilaythong A, Yin XM, Turk B, Noebels JL, Myers RM. Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ. 2003;10(12):1329-35. PMID: 12934064.

30

Kantheti P, Diaz ME, Peden AE, Seong EE, Dolan DF, Robinson MS, et al. Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mamm Genome. 2003;14(3):157-67. PMID: 12647238.

42

Noebels JL. Exploring new gene discoveries in idiopathic generalized epilepsy. Epilepsia. 2003;44 Suppl 2:16-21. PMID: 12752457.

0     

Noebels JL. How a sodium channel mutation causes epilepsy. Epilepsy Curr. 2003;3(2):70-1. PMID: 15309091.

0     

Noebels JL. Stiff goats, chloride ions, and idiopathic generalized epilepsy (IGE). Epilepsy Curr. 2003;3(4):146-7. PMID: 15309062.

209

Noebels JL. The biology of epilepsy genes. Annu Rev Neurosci. 2003;26:599-625. PMID: 14527270.

279

Powell EM, Campbell DB, Stanwood GD, Davis C, Noebels JL, Levitt P. Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction. J Neurosci. 2003;23(2):622-31. PMID: 12533622.

47

Qian J, Noebels JL. Topiramate alters excitatory synaptic transmission in mouse hippocampus. Epilepsy Res. 2003;55(3):225-33. PMID: 12972176.

83

Walz K, Caratini-Rivera S, Bi W, Fonseca P, Mansouri DL, Lynch J, et al. Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: Phenotypic consequences of gene dosage imbalance. Mol Cell Biol. 2003;23(10):3646-55. PMID: 12724422.

20

Anderson E, Berkovic S, Dulac O, Gardiner M, Jain S, Laue Friis M, et al. ILAE genetics commission conference report: Molecular analysis of complex genetic epilepsies. Epilepsia. 2002;43(10):1262-7. PMID: 12366744.

0     

Noebels JL. A gene for JME at last: The alpha1 GABA receptor subunit. Epilepsy Curr. 2002;2(4):131-2. PMID: 15309143.

0     

Noebels JL. Human epilepsy can be linked to a defective calcium channel. Epilepsy Curr. 2002;2(3):95. PMID: 15309155.

12

Noebels JL. Sodium channel gene expression and epilepsy. Novartis Found Symp. 2002;241:109-20; discussion 120-3, 226-32. PMID: 11771641.

38

Poolos NP, Das S, Clark GD, Lardizabal D, Noebels JL, Wyllie E, et al. Males with epilepsy, complete subcortical band heterotopia, and somatic mosaicism for DCX. Neurology. 2002;58(10):1559-62. PMID: 12034802.

584

Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, et al. Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron. 2002;35(2):243-54. PMID: 12160743.

111

Stables JP, Bertram EH, White HS, Coulter DA, Dichter MA, Jacobs MP, et al. Models for epilepsy and epileptogenesis: Report from the NIH workshop, Bethesda, Maryland. Epilepsia. 2002;43(11):1410-20. PMID: 12423393.

144

Zhang Y, Mori M, Burgess DL, Noebels JL. Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons. J Neurosci. 2002;22(15):6362-71. PMID: 12151514.

89

Burgess DL, Gefrides LA, Foreman PJ, Noebels JL. A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. Genomics. 2001;71(3):339-50. PMID: 11170751.

68

Heilstedt HA, Burgess DL, Anderson AE, Chedrawi A, Tharp B, Lee O, et al. Loss of the potassium channel beta-subunit gene, KCNAB2, is associated with epilepsy in patients with 1p36 deletion syndrome. Epilepsia. 2001;42(9):1103-11. PMID: 11580756.

87

Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, et al. Future directions for epilepsy research. Neurology. 2001;57(9):1536-42. PMID: 11706087.

15

Noebels JL. Modeling human epilepsies in mice. Epilepsia. 2001;42 Suppl 5:11-5. PMID: 11887961.

89

Qian J, Noebels JL. Presynaptic Ca2+ channels and neurotransmitter release at the terminal of a mouse cortical neuron. J Neurosci. 2001;21(11):3721-8. PMID: 11356859.

33

Qiao X, Suri C, Knusel B, Noebels JL. Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain-derived neurotrophic factor. J Neurosci Res. 2001;64(3):268-76. PMID: 11319771.

127

Zwingman TA, Neumann PE, Noebels JL, Herrup K. Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a. J Neurosci. 2001;21(4):1169-78. PMID: 11160387.

134

Ayata C, Shimizu-Sasamata M, Lo EH, Noebels JL, Moskowitz MA. Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels. Neuroscience. 2000;95(3):639-45. PMID: 10670432.

10

Burgess DL, Matsuura T, Ashizawa T, Noebels JL. Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13. Epilepsia. 2000;41(1):24-7. PMID: 10643919.

9

Burgess DL, Noebels JL. Calcium channel defects in models of inherited generalized epilepsy. Epilepsia. 2000;41(8):1074-5. PMID: 10961647.

4

Kellaway P, Mizrahi EM, Noebels JL. Benign focal epilepsies of childhood: Genetically determined pathophysiology. Report of an international workshop. Epilepsia. 2000;41(8):1049-50. PMID: 10961636.

130

Lau D, Vega-Saenz de Miera EC, Contreras D, Ozaita A, Harvey M, Chow A, et al. Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins. J Neurosci. 2000;20(24):9071-85. PMID: 11124984.

239

Liu M, Pleasure SJ, Collins AE, Noebels JL, Naya FJ, Tsai MJ, et al. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc Natl Acad Sci U S A. 2000;97(2):865-70. PMID: 10639171.

369

Matsuura T, Yamagata T, Burgess DL, Rasmussen A, Grewal RP, Watase K, et al. Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10. Nat Genet. 2000;26(2):191-4. PMID: 11017075.

95

Qian J, Noebels JL. Presynaptic Ca(2+) influx at a mouse central synapse with Ca(2+) channel subunit mutations. J Neurosci. 2000;20(1):163-70. PMID: 10627593.

73

Steinlein OK, Noebels JL. Ion channels and epilepsy in man and mouse. Curr Opin Genet Dev. 2000;10(3):286-91. PMID: 10826987.

82

Burgess DL, Biddlecome GH, McDonough SI, Diaz ME, Zilinski CA, Bean BP, et al. beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain. Mol Cell Neurosci. 1999;13(4):293-311. PMID: 10328888.

55

Burgess DL, Davis CF, Gefrides LA, Noebels JL. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999;9(12):1204-13. PMID: 10613843.

78

Burgess DL, Noebels JL. Single gene defects in mice: The role of voltage-dependent calcium channels in absence models. Epilepsy Res. 1999;36(2-3):111-22. PMID: 10515159.

49

Burgess DL, Noebels JL. Voltage-dependent calcium channel mutations in neurological disease. Ann N Y Acad Sci. 1999;868:199-212. PMID: 10414295.

6

Clark GD, Noebels JL. Cortin disaster: Lissencephaly genes spell double trouble for the developing brain. Ann Neurol. 1999;45(2):141-2. PMID: 9989613.

112

Hartmann HA, Colom LV, Sutherland ML, Noebels JL. Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain. Nat Neurosci. 1999;2(7):593-5. PMID: 10404176.

39

Noebels JL. Single-gene models of epilepsy. Adv Neurol. 1999;79:227-38. PMID: 10514817.

32

Sutherland ML, Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JL. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc Natl Acad Sci U S A. 1999;96(5):2451-5. PMID: 10051663.

615

Jiang YH, Armstrong D, Albrecht U, Atkins CM, Noebels JL, Eichele G, et al. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 1998;21(4):799-811. PMID: 9808466.

325

Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, et al. Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron. 1998;21(1):111-22. PMID: 9697856.

37

Nahm WK, Noebels JL. Nonobligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and Zif/268 in hippocampal mossy fiber sprouting. J Neurosci. 1998;18(22):9245-55. PMID: 9801364.

2

Noebels JL. Ion channelopathies and heritable epilepsy. News Physiol Sci. 1998;13:255-6. PMID: 11390799.

233

Pennacchio LA, Bouley DM, Higgins KM, Scott MP, Noebels JL, Myers RM. Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice. Nat Genet. 1998;20(3):251-8. PMID: 9806543.

124

Westenbroek RE, Bausch SB, Lin RC, Franck JE, Noebels JL, Catterall WA. Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia. J Neurosci. 1998;18(7):2321-34. PMID: 9502793.

352

Burgess DL, Jones JM, Meisler MH, Noebels JL. Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell. 1997;88(3):385-92. PMID: 9039265.

71

Cattanach BM, Barr JA, Beechey CV, Martin J, Noebels J, Jones J. A candidate model for Angelman syndrome in the mouse. Mamm Genome. 1997;8(7):472-8. PMID: 9195990.

221

Cox GA, Lutz CM, Yang CL, Biemesderfer D, Bronson RT, Fu A, et al. Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell. 1997;91(1):139-48. PMID: 9335342.

63

Di Pasquale E, Keegan KD, Noebels JL. Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer. J Neurophysiol. 1997;77(2):621-31. PMID: 9065835.

257

Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, et al. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1997;94(25):14060-5. PMID: 9391152.

1

Noebels JL, Qiao X, Nahm WK. Neurogenetic approaches to axon sprouting in the hippocampus. Adv Neurol. 1997;72:35-44. PMID: 8993682.

3

Noebels JL, Sutherland ML, Nahm WK, DiPasquale E. Molecular and cellular plasticity in developing epileptic brain. Cold Spring Harb Symp Quant Biol. 1996;61:319-26. PMID: 9246461.

93

Noebels JL. Targeting epilepsy genes. Neuron. 1996;16(2):241-4. PMID: 8789939.

61

Qiao X, Hefti F, Knusel B, Noebels JL. Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia. J Neurosci. 1996;16(2):640-8. PMID: 8551348.

113

Sutherland ML, Delaney TA, Noebels JL. Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. J Neurosci. 1996;16(7):2191-207. PMID: 8601800.

41

Chafetz RS, Nahm WK, Noebels JL. Aberrant expression of neuropeptide Y in hippocampal mossy fibers in the absence of local cell injury following the onset of spike-wave synchronization. Brain Res Mol Brain Res. 1995;31(1-2):111-21. PMID: 7476019.

13

Noebels JL. Single locus mutations in mice expressing generalized spike-wave absence epilepsies. Ital J Neurol Sci. 1995;16(1-2):107-11. PMID: 7642343.

16

Sutherland ML, Delaney TA, Noebels JL. Molecular characterization of a high-affinity mouse glutamate transporter. Gene. 1995;162(2):271-4. PMID: 7557442.

78

Wang H, Allen ML, Grigg JJ, Noebels JL, Tempel BL. Hypomyelination alters K+ channel expression in mouse mutants shiverer and Trembler. Neuron. 1995;15(6):1337-47. PMID: 8845157.

43

Frankel WN, Taylor BA, Noebels JL, Lutz CM. Genetic epilepsy model derived from common inbred mouse strains. Genetics. 1994;138(2):481-9. PMID: 7828829.

19

Helekar SA, Noebels JL. Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering. J Neurophysiol. 1994;71(1):1-10. PMID: 8158221.

24

Buckwalter MS, Testa CM, Noebels JL, Camper SA. Genetic mapping and evaluation of candidate genes for spasmodic, a neurological mouse mutation with abnormal startle response. Genomics. 1993;17(2):279-86. PMID: 8406478.

99

Qiao X, Noebels JL. Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike-wave seizures. J Neurosci. 1993;13(11):4622-35. PMID: 8229188.

113

Wu SM, Qiao X, Noebels JL, Yang XL. Localization and modulatory actions of zinc in vertebrate retina. Vision Res. 1993;33(18):2611-6. PMID: 8296456.

10

Helekar SA, Noebels JL. A burst-dependent hippocampal excitability defect elicited by potassium at the developmental onset of spike-wave seizures in the Tottering mutant. Brain Res Dev Brain Res. 1992;65(2):205-10. PMID: 1572065.

119

Westenbroek RE, Noebels JL, Catterall WA. Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain. J Neurosci. 1992;12(6):2259-67. PMID: 1318958.

27

Helekar SA, Noebels JL. Synchronous hippocampal bursting reveals network excitability defects in an epilepsy gene mutation. Proc Natl Acad Sci U S A. 1991;88(11):4736-40. PMID: 2052555.

55

Noebels JL, Marcom PK, Jalilian-Tehrani MH. Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion. Nature. 1991;352(6334):431-4. PMID: 1713650.

12

Noebels JL. Mutational analysis of spike-wave epilepsy phenotypes. Epilepsy Res Suppl. 1991;4:201-12. PMID: 1815603.

23

Qiao XX, Noebels JL. Genetic and phenotypic heterogeneity of inherited spike-wave epilepsy: Two mutant gene loci with independent cerebral excitability defects. Brain Res. 1991;555(1):43-50. PMID: 1933329.

174

Noebels JL, Qiao X, Bronson RT, Spencer C, Davisson MT. Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy Res. 1990;7(2):129-35. PMID: 2289471.

34

Noebels JL, Rutecki PA. Altered hippocampal network excitability in the hypernoradrenergic mutant mouse tottering. Brain Res. 1990;524(2):225-30. PMID: 2292005.

38

Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. J Neurogenet. 1989;6(1):53-6. PMID: 2778559.

34

Noebels JL. Mutational analysis of inherited epilepsies. Adv Neurol. 1986;44:97-113. PMID: 2871726.

119

Noebels JL. A single gene error of noradrenergic axon growth synchronizes central neurones. Nature. 1984;310(5976):409-11. PMID: 6462226.

38

Noebels JL. Isolating single genes of the inherited epilepsies. Ann Neurol. 1984;16 Suppl:S18-21. PMID: 6095738.

145

Levitt P, Noebels JL. Mutant mouse tottering: Selective increase of locus ceruleus axons in a defined single-locus mutation. Proc Natl Acad Sci U S A. 1981;78(7):4630-4. PMID: 6945603.

268

Noebels JL, Sidman RL. Inherited epilepsy: Spike-wave and focal motor seizures in the mutant mouse tottering. Science. 1979;204(4399):1334-6. PMID: 572084.

52

Noebels JL. Analysis of inherited epilepsy using single locus mutations in mice. Fed Proc. 1979;38(10):2405-10. PMID: 383515.

60

Noebels JL, Prince DA. Development of focal seizures in cerebral cortex: Role of axon terminal bursting. J Neurophysiol. 1978;41(5):1267-81. PMID: 702194.

28

Noebels JL, Prince DA. Excitability changes in thalamocortical relay neurons during synchronous discharges in cat neocortex. J Neurophysiol. 1978;41(5):1282-96. PMID: 212538.

24

Noebels JL, Roth WT, Kopell BS. Cortical slow potentials and the occipital EEG in congenital blindness. J Neurol Sci. 1978;37(1-2):51-8. PMID: 690664.

39

Noebels JL, Pedley TA. Anatomic localization of topically applied [14C]penicillin during experimental focal epilepsy in cat neocortex. Brain Res. 1977;125(2):293-303. PMID: 404001.

42

Noebels JL, Prince DA. Presynaptic origin of penicillin after discharges at mammalian nerve terminals. Brain Res. 1977;138(1):59-74. PMID: 201346.

45

Schwartzkroin PA, Futamachi KJ, Noebels JL, Prince DA. Transcallosal effects of a cortical epileptiform focus. Brain Res. 1975;99(1):59-68. PMID: 1188986.