Developmental Neurogenetics Laboratory

Click on the Expand plus sign sign to list the poster and platform presentations by year. Then click on the link to view that presentation.

2023

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    American Epilepsy Society (AES)
    77th Annual Meeting in Orlando, Fla. (Dec. 1-5, 2023)
    • Actigraphic signatures of disability in adults with epilepsy and intellectual disability.

      Adhyapak N, Krishna Rao P, Kamen J, Abboud M, Krishnan V

    • Cortical spreading depression.
      [Oral Presentation]

      Aiba I

    • Spreading depolarization in gain-of-function Scn8a mice resembles that of Kcnq2 deficient mice.

      Aiba I, Ning Y, Noebels J

    • Antiseizure medication-induced hypersensitivity reactions in a large healthcare system.

      Cadle B, Un Candan F, Haneef Z, Barton C, Brock D, Ali I, et al.

    • Cell type-specific circuit mechanisms of absence epilepsy.

      Jiang X, Maheshwari A, Miao Q, Noebels J, Song S

    • Sexually dimorphic behavioral and metabolomic consequences of prenatal valproic acid exposure.

      Karedia S, Mazumder AG, Kamen J, Krishnan V

    • Approaches to ascertain emotional and psychiatric comorbidities in experimental models of epilepsy.
      [Oral Presentation]

      Krishnan V

    • Clinicopathologic dissociation: Robust age-dependent Lafora body accumulation in Malin-KO mice without observable changes in home-cage behavior.

      Krishnan V, Wu J, Mazumder AG, Kamen J, Bass III J, Maheshwari A, et al.

2022

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    American Epilepsy Society (AES)
    76th Annual Meeting in Nashville, Tenn. (Dec. 2-6, 2022)
    • Encephalopathy in kv1.1 KO mice is associated with hippocampal BDNF and EGR3.

      Mazumder AG, Kamen J, Bass J, Schirmer C, Krishnan V

    • Nonlinear dysregulation of glutamate and neural activity facilitates glioma-induced epilepsy.

      Meyer J, Yu K, Deneen B, Noebels J

    • A digenic mechanism for absence epilepsy.

      Miao Q-L, Noebels J

    • Emx1-Cre is expressed in peripheral neurons that regulate cardiorespiratory tone.

      Ning Y, Noebels J, Aiba I

    • mTOR complexes in epilepsy and seizure disorders.

      Okoh J, Mays J, Bacq A, Zhou H, Imanbeyev K, Jafar-Nejad P, et al.

    Society for Neuroscience (SFN)
    52nd Annual Meeting in San Diego, Calif. (Nov. 12-16, 2022)
    • Dissecting the role of mTOR complexes in epilepsy and seizure disorders.

      Okoh JT, Mays JL, Bacq A, Imanbayev K, Zhou H, Jafar-Nejad P, et al.

    • Layer- and cell type- specific cortical circuit deficits underlying the absence epilepsy.

      Song S, Maheshwari A, Noebels JL, Jiang X

    • Transcriptional dysregulation of thalamic t-type calcium channel gene precedes seizure onset in childhood absence epilepsy mouse model tottering.

      Thompson S, Sonig A, Noebels J

    American Neurological Association (ANA)
    147th Annual Meeting in Chicago, Ill. (Oct. 22-25, 2022)
    • Actigraphic correlates of psychiatric disability in patients with focal epilepsy.

      Abboud MA, Kamen JL, Gavvala JR, Lin L, Krishnan V

<2021

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    American Epilepsy Society (AES)
    75th Annual Meeting in Chicago, Ill. (Dec. 3-7, 2021)
    • Spontaneous cortical spreading depolarization in a SCN1A deficient Dravet syndrome mouse model.

      Aiba I, Ning Y, Noebels J

    • System xc: Friend or foe in KCNA1-null mice?

      Aloi M, Noebels J

    • On the mental status of Stargazer mice.

      Krishnan V, Abboud M, Lee S, Bass J, Schirmer C, Mazumder A

    • Actigraphic correlates of disability in patients with focal epilepsy.

      Lin L, Abboud M, Bass J, Gavvala J, Krishnan V

    • On the digital psychopharmacology of antiseizure medications.

      Mazumder A, Bass J, Lee S, Schirmer C, Krishnan V

    • Making absence epilepsy by combining two epilepsy genes.

      Miao Q, Noebels J

    • Fenfluramine directly inhibits cortical spreading depolarization&emdash;A pathophysiologic process linked to SUDEP.

      Ning Y, Reeder T, Noebels J, Aiba I

    • Transcriptional dysregulation of thalamic T-type calcium channel CACNA1G gene precedes seizure onset in childhood absence epilepsy mouse model tottering.

      Thompson S, Sonig A, Noebels J

    Society for Neuroscience (SFN)
    Virtual Annual Meeting (Nov. 8-11, 2021)
    • Layer- and pathway-specific disruption of perisomatic inhibition in the somatosensory cortex of the stargazer model of absence epilepsy.

      Song S-Y, Maheshwari A, Noebels JL, Jiang X

    American Clinical Neurophysiology Society (ACNS)
    Virtual 2021 Annual Meeting (Feb. 10-14, 2021)
    • The utility of additional depth or subdural electrodes following stereotactic EEG evaluation.

      Karimov A, Gavvala J, Goldman A, Haneef Z, Maheshwari A, Sheth S, et al.

    American Epilepsy Society (AES)
    74th Annual Meeting in Seattle, Wash. (Dec. 4-8, 2020)
    • Actigraphic correlates of disability in patients with focal epilepsy.

      Bass J, Kapadia P, Gavvala J, Krishnan V

    • Epileptic encephalopathy in KCNA1 KO mice disrupts active state organization.

      Krishnan V, Schirmer C, Jankovic M, Kapadia P, Bass J

    • Deficits in 5-HT2C receptor signaling coordinately impact seizure risk and behavioral activity.

      Massey C, Thompson S, Jankovic M, Bass J, Krishnan V, Noebels JL

    • On the digital psychopharmacology of valproic acid in mice: Adult and prenatal exposure.

      Schirmer C, Ton L, Tuo A, Jankovic M, Kapadia P, Krishnan V

    American Neurological Association (ANA)
    145th Annual Meeting in Los Angeles, Calif. (Oct. 4-6, 2020)
    • Epileptic encephalopathy in Kcna1 KO mice disrupts active state organization.

      Bass J, Schirmer C, Jankovic M, Kapadia P, Krishnan V

    American Epilepsy Society (AES)
    73rd Annual Meeting in Baltimore, Md. (Dec. 6-10, 2019)
    • Mice lacking 5-HT2C receptors have a lowered spreading depolarization threshold compared to wildtype littermates.

      Massey CA, Noebels JL

    • Arx mouse model of x-linked infantile spasms shows augmented wave of early cortical apoptosis without evidence of cellular inflammation.

      Siehr MS, Massey CA, Noebels JL

    Society for Neuroscience (SFN)
    49th Annual Meeting in Chicago, Ill. (Oct. 19-23, 2019)
    • Cav3.1 and 3.2 T-type Ca2+ channels collectively contribute to oscillatory excitation of nucleus ambiguus neurons.

      Aiba I, Noebels JL

    • A genetic cross between Gad2-Cre and loxTB Htr2c mouse strains does not prevent seizures and death in a 5-HT2C-null SUDEP mouse model.

      Massey CA, Noebels JL

    • Progression of cortical hypersynchrony and epileptogenesis induced by brain tumors.
      [Platform Presentation]

      Meyer JF, Yu K, Hatcher A, Aiba I, Deneen B, Noebels JL

    • Mice with adult-onset P/Q calcium channel deletion recapitulates childhood absence epilepsy.

      Miao QM, Noebels JL

    American Epilepsy Society (AES)
    72nd Annual Meeting in New Orleans, La. (Nov. 30 - Dec. 4, 2018)
    • Tau loss modifies network excitability in brain tumor-related epilepsy.

      Hatcher A, Yu K, Noebels JL, Deneen B

    • Functional involvement of periventricular nodular heterotopia.

      Houck KM, Haneef Z, Nayak A, Gavvala J, Quach MM, Van Ness PC, et al.

    • An objective description of PTZ kindling in a standardized instrumented home cage environment.

      Jankovic M, Krishnan V

    • Home cage monitoring reveals the presence of comorbid depression-related behavior in mice with deletions of Kcna1.

      Krishnan V, Jankovic M, Noebels JL

    • Mice lacking 5-HT2C receptors display a novel adult-onset SUDEP phenotype and increased mortality in males.

      Massey C, Noebels JL

    • Conditional deletion of PQ-type calcium channels in kainate receptor4 (Grik4)-expressing hippocampal neurons leads to adult onset absence epilepsy.

      Miao Q, Noebels JL

    Society for Neuroscience (SFN)
    48th Annual Meeting in San Diego, Calif. (Nov. 3-7, 2018)
    • Interictal dentate gyrus hyperexcitation in a mouse model of Dravet syndrome.

      Aiba I, Noebels JL

    • Dysregulation of mTORC2, but not mTORC1, underlies the neurophysiological and behavior abnormalities in Pten-deficient mouse model of ASD and epilepsy.

      Chen CJ, Sgritta M, Mays J, Noebels J, Costa-Mattioli M

    • Tau loss modifies network excitability in brain tumor related epilepsy.

      Hatcher A, Yu K, Aiba I, Deneen B, Noebels JL

    • β-spectrins maintain Na+ channels at axon initial segments and nodes of Ranvier.

      Liu CH, Stevens S, Seo R, Mohler P, Noebels J, Stankewich M, et al.

    • T-type calcium channel bursting in thalamic association pathways precedes sensory pathways and can be activated by GABAergic input during early postnatal development.

      Miao Q, Noebels JL

    American Epilepsy Society (AES)
    71st Annual Meeting in Washington, DC (Dec. 1-5, 2017)
    • Tau loss modifies network excitability in glioma-associated epilepsy.

      Hatcher A, Yu K, Aiba I, Deneen B, Noebels J

    • Evidence for brainstem network disruption in focal epilepsy and sudden unexplained death in epilepsy: A first validation study.

      Mueller SG, Nei M, Bateman L, Knowlton R, Laxer K, Friedman D, et al.

    Society for Neuroscience (SFN)
    47th Annual Meeting in Washington, DC (Nov. 11-15, 2017)
    • mTORC2 dysfunction underlies the neuronal physiological and behavioral abnormalities in Pten-deficient mouse model of autism.

      Chen C-J, Sgritta M, Lucero RD, Noebels JL, Costa-Mattioli M

    • Development of T-type calcium channel bursting in thalamic association pathway precedes sensory pathways.

      Miao Q, Noebels JL

    • Adrenergic signaling promotes T-type Ca2+ channel mediated oscillatory discharges in nucleus ambiguus neurons.

      Noebels JL, Aiba I

    American Neurological Association (ANA)
    142nd Annual Meeting in San Diego, Calif. (Oct. 15-17, 2017)
    • Clinical utility of genetic testing in adults with epilepsy: 4-year experience of the Baylor Genetic Epilepsy Clinic.

      Marafie D, Rosenfeld J, Van Ness P, Zohrevand P, Haneef Z, Chen D, et al.

    American Epilepsy Society (AES)
    70th Annual Meeting in Houston, Texas (Dec. 2-6, 2016)
    • Center for SUDEP Research: Brainstem atrophy in SUDEP.

      Bateman L, Nei M, Goldman A, Mueller S

    • The role of tau in modulating hyper excitability in an emerging model of tumor associated epilepsy.

      Hatcher A, Yu K, Lalonde J, Deneen B, Noebels J

    • Dynamics of gamma oscillations in a mouse model of absence epilepsy.

      Maheshwari A, Marks R, Davalos-Balderas A, Wang M, Noebels J

    • Clinical utility of genetic testing in adults with epilepsy: Pilot experience of the Baylor genetic epilepsy clinic.

      Marafie D, Rosenfeld J, Van Ness P, Zohrevand P, Haneef Z, Chen D, et al.

    • Asynchronous suppression of superficial cortex during absence seizures.
      [Platform Presentation]

      Meyer J, Maheshwari A, Noebels J, Smirnakis S

    • A critical developmental window for 17β-estradiol antiepileptogenic effect in a mouse model of X-linked infantile spasms.

      Siehr M, Lucero R, Lalonde J, Noebels J

    Society for Neuroscience (SFN)
    46th Annual Meeting in San Diego, Calif. (Nov. 12-16, 2016)
    • Characterization of a polysynaptic microcircuit involved in sensory vagal afferent activation of dorsomotor vagal neurons in mouse.

      Aiba I, Noebels JL

    • The role of tau in modulating hyper-excitability in an emerging model of tumor associated epilepsy.

      Hatcher A, Yu K, Lalonde J, Deneen B, Noebels J

    • αII-spectrin-dependent cytoskeletons are essential for axon function, domain assembly and integrity.

      Huang Y, Zhang C, Zollinger D, Lalonde J, Leterrier C, Noebels J, et al.

    • Early development of thalamic low-threshold T-type calcium current in the VPM of C57BL/6 mice.

      Miao Q, Noebels JL

    • A critical developmental window for 17β-estradiol antiepileptogenic effect in a mouse model of X-linked infantile spasms.

      Siehr M, Lucero R, Lalonde J, Noebels J

    American Neurological Association (ANA)
    141st Annual Meeting in Baltimore, Md. (Oct. 16-18, 2016)
    • Prevalence and character of severe epileptic encephalopathy in patients affected by MECP2 duplication syndrome.

      Marafie D, Schultz R, Glaze D, Suter B, Goldman A

    • Dynamic participation patterns of superficial cortex during absence seizures.

      Meyer JF, Maheshwari A, Noebels JL, Smirnakis SM

    Federation of American Societies for Experimental Biology (FASEB)
    Science Research Conference (Neural Mechanisms in Cardiovascular Regulation: Novel Research and Disease Treatment Strategies) in Saxtons River, Vt. (July 17-22, 2016)
    • Polysynaptic activation of dorsomotor vagal neurons by sensory afferent nerve.

      Aiba I, Noebels JL

    American Academy of Neurology (AAN)
    68th Annual Meeting in Vancouver, BC, Canada (April 15-21, 2016)
    • Severe epileptic encephalopathy is a frequent neurological comorbidity of children affected by the MECP2 duplication syndrome.
      [Oral Presentation]

      Marafie D, Schultz R, Glaze D, Goldman A, Suter B

    American Epilepsy Society (AES)
    69th Annual Meeting in Philadelphia, Penn. (Dec. 4-8, 2015)
    Society for Neuroscience (SFN)
    45th Annual Meeting in Chicago, Ill. (Oct. 17-21, 2015)
    • Cardiac arrhythmogenic leaky ryanodine receptor 2 mutation increases cortical excitability and lowers threshold for spreading depolarization in mouse brain.

      Aiba I, Noebels JL

    31st International Epilepsy Congress (IEC)
    Istanbul, Turkey (Sept. 5-9, 2015)
    • Neonatal estradiol prevents infantile spasms and seizures in arx-linked infantile spasms syndrome.
      [Platform Presentation]

      Noebels JL

    American Epilepsy Society (AES)
    68th Annual Meeting in Seattle, Wash. (Dec. 5-9, 2014)
    • Treatment resistance correlates with ECG abnormalities in a pilot clinical surveillance of epilepsy patients.

      Zohrevand P, Diaz M, Amador A, Goldman A

    Society for Neuroscience (SFN)
    44th Annual Meeting in Washington, DC (Nov. 15-19, 2014)
    • Increased risk of hypoxic depolarization of the brainstem autonomic circuit in a mouse SUDEP model.

      Aiba I, Noebels JL

    American Academy of Neurology (AAN)
    66th Annual Meeting in Philadelphia, Penn. (April 26 - May 3, 2014)
    American Epilepsy Society (AES)
    67th Annual Meeting in Washington, DC (Dec. 6-10, 2013)
    • Lateralization of temporal lobe epilepsy with long-term ambulatory intracranial monitoring using the RNS system: Experience in 82 patients.

      King-Stephens D, Mirro E, Weber P, Laxer K, Van Ness P, Salanova V, et al.

    • STOP SUDEP Program: Application of visual automated fluorescence electrophoresis in the qualitative profiling of archived SUDEP samples.

      Klassen TL, Tomson T, Sveinsson O, von Dobeln U, Drabek J, Noebels J, et al.

    • In vivo 2-photon confocal microscopy of cortical absence epilepsy.

      Meyer JF, Maheshwari A, Noebels J, Smirnakis S

    Society for Neuroscience (SFN)
    43rd Annual Meeting in San Diego, Calif. (Nov. 9-13, 2013)
    • Bexarotene decreases hyperexcitability in two mouse models with epilepsy.

      Bomben VC, Holth JK, Cramer PE, Landreth GE, Noebels JL

    • Genetic ablation of betaII-spectrin in the central nervous system results in axon degeneration, epilepsy and postnatal lethality.

      Zhang C, Huang Y-M, Zhu P, Reed JG, Costa-Mattioli M, Noebels JL, et al.

    American Neurological Association (ANA)
    138th Annual Meeting in New Orleans, La. (Oct. 13-15, 2013)
    • Sudden unexplained death in epilepsy: Can genomics help?
      [Plenary Talk]

      Goldman A

    Alzheimer's Association, Houston and Southeast Texas Chapter
    7th Annual Research Symposium on Alzheimer's Disease (Sept. 12, 2013)
    American Epilepsy Society (AES)
    66th Annual Meeting in San Diego, Calif. (Nov. 30 - Dec. 4, 2012)
    • SUDEP Tissue Donation Program (STOP): Collaborative network in support of SUDEP registry, tissue repository and human translational research.

      Goldman AM

    • Universal DNA extraction protocol for the utilization of alternative tissue sources in downstream epilepsy genetic analysis.

      Goldman AM, Klassen TL, von Rueden EL, Drabek JM, Noebels JL

    • SUDEP research consortium: A new collaborative network to discover predictive genes, mechanisms and biomarkers of SUDEP.
      [Investigators' Workshop]

      Goldman AM, Richerson G, Parent JM, Bateman L, Nordli DR, Noebels JL

    • Loss of tau protein reduces hyperexcitability in mouse and drosophila genetic models of epilepsy.

      Holth J, Reed JG, Inoue T, Pautler R, Botas J, Noebels JL

    • Myotonia in brain: 'Skeletal' chloride channel ClC-1 linked to idiopathic generalized epilepsy with focal myotonia.

      Klassen TL, Chen TT, Reed JG, Kole MJ, Goldman AM, Marini C, et al.

    • Channotyping epilepsy: Profiling personal variation in ion channel genes.

      Klassen TL, Goldman A, Davis C, Chen T, Gibbs R, Noebels J

    • 17?-estradiol decreases seizure and interictal spike frequency in a genetic mouse model of X-linked infantile spasms.

      Olivetti PR, Noebels JL

    Society for Neuroscience (SFN)
    42nd Annual Meeting in New Orleans, La. (Oct. 13-17, 2012)
    • Neuronal Elavl proteins regulate RNA splicing and abundance to control brain glutaminase expression and neuronal excitability.

      Ince Dunn G, Okana HJ, Okana H, Jensen K, Park W-Y, Mele A, et al.

    2011 International Society for Zinc Biology (ISZB)
    Meeting in Melbourne, Australia (Jan. 15-19, 2012)
    • Intracellular dialysis can be exploited to distinguish sources of intracellular Zn2+ accumulation in hippocampal neurons.

      Aiba I, Shuttleworth CW

    American Epilepsy Society (AES)
    65th Annual Meeting in Baltimore, Md. (Dec. 2-6, 2011)
    • Dendritic AMPA receptor deficit on cortical interneurons in the stargazer mouse model of absence epilepsy.

      Maheshwari A, Reed JG, Noebels JL

    Society for Neuroscience (SFN)
    41st Annual Meeting in Washington, DC (Nov. 12-16, 2011)
    • NMDA receptor activation prolongs the duration of ionic dyshomeostasis following spreading depolarization in murine brain slices.

      Aiba I, Shuttleworth CW

    • Propagation of spreading depolarizations is limited by the synaptic release and extracellular actions of Zn2+.

      Carter RE, Aiba I, Carlson AP, Sheline CT, Shuttleworth CW

    • Flupirtine reverses hyperexcitability in Kv1.1 potassium channel deficient myelinated vagal axons.

      Glasscock E, Qian J, Kole MJ, Noebels JL

    • Tau loss regulates excitability in mouse and Drosophila genetic models of epilepsy.

      Holth J, Reed JG, Inoue T, Pautler R, Botas J, Noebels J

    • ADAM11 is responsible for trafficking of Kv1 subunits to cerebellar basket cell terminals.

      Kole MJ, Waase MP, Klassen TL, Chen TT, Breslow JL, Noebels JL

    • Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia.

      Mark MD, Maejima T, Kuckelsberg D, Woo JW, Hyde RA, Shah V, et al.

    • Early 17-beta-estradiol treatment decreases seizure and interictal spike frequency in the ARX(GCG)10+7 genetic mouse model of X-linked infantile spasms.

      Olivetti PR, Noebels JL

    • Suppression of the protein kinase PKR promotes network hypersynchrony and enhanced cognition.

      Zhu P, Huang W, Kalikulov D, Yoo J, Placzek A, Stoica L, et al.

    Gordon Research Conferences (GRC)
    Excitatory Synapses & Brain Function Meeting in Easton, Mass. (June 26 - July 1, 2011)
    • NMDA-R activation contributes to metabolic burden following spreading depolarization in murine hippocampal slices.

      Aiba I, Shuttleworth CW

    American Academy of Neurology (AAN)
    63rd Annual Meeting in Honolulu, Hawaii (April 9-16, 2011)
    • Coding and decoding pathogenic ion channels in epilepsy.

      Noebels J

    American Epilepsy Society (AES)
    64th Annual Meeting in San Antonio, Texas (Dec. 3-7, 2010)
    • High resolution copy number variation of ion channel genes in epilepsy.

      Goldman A, Klassen T, Gu W, Zhang F, Bomben V, Chen T, et al.

    Society for Neuroscience (SFN)
    40th Annual Meeting in San Diego, Calif. (Nov. 13-17, 2010)
    • Metabolic dependence of zinc effects on spreading depression in murine brain slices.

      Aiba I, Shuttleworth CW

    • MeCP2 deficiency in GABAergic neurons recapitulates Rett syndrome phenotypes.

      Chao H-T, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, et al.

    American Society for Neurochemistry (ASN)
    41st Annual Meeting in Santa Fe, N.M. (March 6-10, 2010)
    • Different roles of extracellular and intracellular Zn2+ in spreading depression-like events in hippocampal slice.

      Aiba I, Dietz RM, Sheline CT, Shuttleworth CW

    Baylor College of Medicine (BCM)
    20th Annual Rush and Helen Record Neuroscience Forum in Galveston, Texas (Feb. 19-21, 2010)
    American Epilepsy Society (AES)
    63rd Annual Meeting in Boston, Mass. (Dec. 4-8, 2009)
    • Spontaneous epilepsy and neuronal hyperexcitability in Kv12.2 -/- mice.

      Bertaso F, Zhang X, Yoo J, Schmedt C, Clancy S, Noebels JL, et al.

    • Long QT mouse model links the dual phenotype of cardiac arrhythmias and epilepsy with sudden unexplained death in epilepsy.

      Goldman A, Glasscock E, Yoo J, Chen T, Klassen T, Noebels J

    Society for Neuroscience (SFN)
    39th Annual Meeting in Chicago, Ill. (Oct. 17-21, 2009)
    • MeCP2 regulation of GABAergic neuronal function modulates behavior and synaptic plasticity.

      Chao H-T, Chen H, Samaco RC, Chahrour M, Xue M, Yoo J, et al.

    • MeCP2 regulation of GABAergic neuronal function modulates behavior and synaptic plasticity.

      Chao H-T, Chen H, Samaco RC, Chahrour M, Xue M, Yoo J, et al.

    • Non-convulsive seizure phenotypes and dementia in mice and humans.

      Noebels JL

    • Spontaneous epilepsy and neuronal hyperexcitability in Kv12.2 -/- mice.

      Zhang X, Bertaso F, Yoo J, Schmedt C, Clancy S, Noebels JL, et al.

    28th International Epilepsy Congress (IEC)
    Budapest, Hungary (June 29 - July 2, 2009)
    • Human KvLQT1 mutations in mice link the dual phenotype of cardiac arrhythmias and epilepsy with sudden unexplained death in epilepsy.

      Goldman A, Glasscock E, Yoo J, Chen T, Klassen T, Noebels J

    • Summary of the U.S. National Institute of Neurological Disorders and Stroke (NINDS) Workshop on SUDEP.

      So EL, Hirsch JL, Donner JE, Noebels JL, Jacobs PM, Buchhalter RJ

    American Epilepsy Society (AES)
    62nd Annual Meeting in Seattle, Wash. (Dec. 5-9, 2008)
    Society for Neuroscience (SFN)
    38th Annual Meeting in Washington, DC (Nov. 15-19, 2008)
    • Kcna1 is a novel candidate gene for sudden unexplained death in epilepsy (SUDEP).

      Glasscock E, Yoo JW, Noebels JL

    Mechanisms of Epilepsy and Neuronal Synchronization
    Gordon Research Conference in Waterville, Maine (Aug. 3-8, 2008)
    • Kcna1 is a novel candidate gene for sudden unexplained death in epilepsy (SUDEP).

      Glasscock E, Yoo JW, Noebels JL

    American Epilepsy Society (AES)
    61st Annual Meeting in Philadelphia, Penn. (Nov. 30 - Dec. 4, 2007)
    • Growth curve analysis of changes in spatial and verbal learning characteristics after anterior temporal lobectomy.

      Dulay MF, Levin HS, Mizrahi EM, York MK, Li X, Goldsmith IL, et al.

    • Masking epilepsy by combining two epilepsy mutations.

      Glasscock E, Qian J, Yoo JW, Noebels JL

    • Genomic research in the era of identifiable genetic information.

      Goldman AM, McGuire AL, Hilsenbeck SG, Noebels JL

    • Varied roles of BK-type potassium channels in the regulation of neuronal excitability: Which are important for epilepsy?

      Sanchez RM, Storm JF, Richerson GB, Barth A, Noebels JL

    American Epilepsy Society (AES)
    60th Annual Meeting in San Diego, Calif. (Dec. 1-5, 2006)
    • Expression profile of voltage-gated sodium channel genes in two knockout mouse models exhibiting spontaneous seizures.

      Ernst SJ, Isom L, Burgess DL, Noebels JL

    • Development of a transgenic mouse model of spike-wave epilepsy by overexpression of α1G T-type calcium channels.

      Ernst WL, Yoo JW, Burgess DL, Noebels JL

    • The prevalence of inter-ictal cardiac arrhythmias and LQT gene variants in patients with idiopathic epilepsy.

      Goldman AM, Burgess DL, Gibbs RA, Chapman KE, Wilfong AA, Hrachovy RA, et al.

    Mechanisms of Epilepsy and Neuronal Synchronization
    Gordon Research Conference in Waterville, Maine (Aug. 6-11, 2006)
    • Ion channel gene interactions in inherited epilepsy.

      Glasscock E, Yoo J, Noebels JL

    American Epilepsy Society (AES)
    58th Annual Meeting in New Orleans, La. (Dec. 3-7, 2004)
    • Absence of mossy fibers in NeuroD/BETA2 null mice prevents pilocarpine-induced status epilepticus.

      Mori M, Liu M, Cho JH, Ming-Jer TL, Noebels JL

    • Secretion and functional analysis of LGI/Epitempin family members.

      Senechal KR, Noebels JL

    American Epilepsy Society (AES)
    57th Annual Meeting in Boston, Mass. (Dec. 5-10, 2003)
    • Regional and developmental localization of ion-channel genes coexpressed in heart and brain.

      Goldman AM, Burgess DL, Armstrong DD, Mori M, Noebels JL

    • Expression of apoptosis inhibitor protein MCL1 linked to neuroprotection in CNS neurons.

      Mori M, Burgess DL, Gefrides LA, Armstrong D, Foreman PJ, Opferman JT, et al.

    • Presidential symposium: The developing epileptic brain.

      Noebels JL, Walsh CA, Levitt PR, Barres BA

    • Elevated T-type calcium currents in thalamic neurons are associated with spike-wave seizure generation in the mouse mutant Coloboma (Cm/+).

      Zhang Y, Vilaythong AP, Noebels JL

    25th International Epilepsy Congress (IEC)
    Lisbon, Portugal (Oct. 12-16, 2003)
    • Expression pattern of candidate epilepsy ion channel genes in mouse and human brains.

      Goldman AM, Burgess DL, Armstrong DD, Mori M, Noebels JL

    American Epilepsy Society (AES)
    56th Annual Meeting in Seattle, Wash. (Dec. 6-11, 2002)
    • EEG abnormalities and epilepsy in Smith-Magenis syndrome and in a genetic mouse model.

      Lynch JK, Walz K, Glaze DG, Potocki L, Lupski JR, Noebels JL

    • The effect of topiramate on excitatory synaptic transmission in mouse hippocampus.

      Qian J, Noebels JL

    American Epilepsy Society (AES)
    55th Annual Meeting in Philadelphia, Penn. (Nov. 30 - Dec. 5, 2001)
    • Magnetoencephalography mislocalizes interictal epileptogenic activity in mesial temporal epilepsy.

      Goldman AM, Wheless JW, Venkataraman V, Kim HL, Papanicolaou AC

    • Differential early expression of novel genes in the hippocampus after pilocarpine-induced status epilepticus in inbred mouse strains with high and low seizure susceptibility.

      Mori M, Burgess DL, Gefrides L, Foreman PJ, Naffah-Mazzacoratti MG, Noebels JL

    • Increased calcium currents in thalamocortical relay cells of tottering and lethargic mice.

      Zhang Y, Noebels JL

    American Epilepsy Society (AES)
    54th Annual Meeting in Los Angeles, Calif. (Dec. 1-6, 2000)
    • Genetic aggregation of calcium channel defects in mice simulates non-Mendelian inherited human epilepsy.

      Burgess DL, Gefrides LA, Davis CF, Noebels JL

    • Expression of a family of calcium channel γ-subunits (CACNG 1-8) in mice.

      Foreman PJ, Burgess DL, Gefrides LA, Noebels JL

    • Absence of pilocarpine-induced status epilepticus in NeuroD knock out mice.

      Mori M, Min L, Ming TJ, Noebels JL

    • Changes in presynaptic Ca currents and transmitter release are synapse-dependent in epileptic mice with calcium channel mutations.

      Qian J, Noebels JL

    • Altered calcium currents in thalamocortical relay cells of stargazer, a mouse epilepsy model caused by a calcium channel gamma sub-unit mutation.

      Zhang Y, Noebels JL

    American Epilepsy Society (AES)
    51st Annual Meeting in Boston, Mass. (Dec. 7-10, 1997)
    • Mutation of the voltage-dependent calcium channel beta subunit gene Cchb4 is associated with absence seizures and ataxia in the lethargic (lh) mouse.

      Burgess DL, Jones JM, Meisler MH, Zilinski CA, Noebels JL

    • A mutation in the sodium/hydrogen exchanger-1 gene causes ataxia and epilepsy in the slow-wave epilepsy mutant mouse.

      Cox GA, Lutz CM, Biemesderfer D, Bronson RT, Aronson PS, Noebels JL, et al.

    • Subtype-specific downregulation of glutamate transporter gene expression in three models of temporal lobe epilepsy.

      Sutherland ML, Delaney TA, Noebels JL