May 18 – 20, 2012
Houston Marriott
at the Texas Medical Center
6580 Fannin St.
Houston, Texas 77030
Dear Conference Participants:
We are excited to welcome you to the Second Neurocritical Care Research Conference and to Houston. We hope you will find the next 2½ days as stimulating as it has been for us the planning of this great event. This symposium has been funded by NINDS (1R13NS077610-01, P.I. Jose I. Suarez), St Luke’s Episcopal Hospital in Houston, and the Integra Foundation, and endorsed by the Baylor College of Medicine and the Neurocritical Care Society.
The overall goal of this interdisciplinary scientific gathering is to bring together a diverse group of academic scientists and physicians from diverse fields with a common interest in understanding and advancing research in multimodality monitoring in neurocritical care diseases. The symposium is unique in that it will provide a forum for presenting and discussing the latest advances in clinical trial design, research tools, and research priorities in the field of neuromonitoring. The need for the design of adequate clinical studies to test these monitoring techniques will also be addressed in the context of the recently created Neurocritical Care Research Network (NCRN) to facilitate collaboration and patient enrollment. In addition, this conference will provide a unique opportunity for trainees, junior faculty, and other scientists to interact with investigators in the field of neurocritical care.
At the conclusion of this program, participants will be able to:
- Understand the importance and opportunities for research in multimodality monitoring in neurocritical care diseases
- Discuss recent scientific advances related to conventional and alternative clinical trial design and research tools that will have an impact on multimodality monitoring research;
- Determine the future directions of research of multimodality neuromonitoring;
- Initiate collaborations via NCRN and other networks for multimodality neuromonitoring research.
We expect and encourage you to participate actively in the discussions following each session since your thoughts will be extremely important to complement the presentations. Your presence for the entire conference will be required. Session moderators and conference organizers will collate the information discussed throughout the meeting and prepare summary statements for publication in Neurocritical Care. In addition, we will be videotaping the entire event and the formatted videos will be posted at the website of the Neurocritical Care Society for public access.
All activities related to this conference will take place at the Marriott Houston at the Texas Medical Center (6580 Fannin St., Houston, TX 77030). We appreciate and thank you for your participation.
Sincerely,
Jose I. Suarez, M.D.
Peter D. LeRoux, M.D.
Speakers and Planning Committee
Organizing Committee
Jose I. Suarez, M.D. Professor of Neurology |
Peter D. LeRoux, M.D. Associate Professor of Neurosurgery |
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Professor of Neurosurgery, Anesthesiology and Critical Care |
Eusebia Calvillo, R.N. Research Coordinator |
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Theresa Kukic Conference Management Solutions |
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Speakers
Randall Chestnut, M.D.
Professor of Neurological Surgery, and Orthopaedics & Sports Medicine
University of Washington
Seattle, WA
Giuseppe Citerio, M.D.
Director of Neuroanesthesia and Neuro Intensive Care Unit
San Gerardo Hospital
Monza, Italy
Professor of Critical Care Medicine and Pediatrics
University of Pittsburgh
Pittsburgh, PA
Professor of Neurology and Neurosurgery
Washington University
St Louis, MO
Associate Professor of Anesthesiology/Critical
Care Medicine
Johns Hopkins University
Baltimore, MD
Puneet Gupta, M.D., M.S.E.
Assistant Professor of Neurology and Neurotherapeutics
University of Texas Southwestern
Dallas, TX
Claude Hemphill III, M.D.
Professor of Clinical Neurology and Neurological Surgery
University of California, San Francisco
San Francisco, CA
Peter J. Kirkpatrick
University of Cambridge
Cambridge, United Kingdom
Professor of Neurosurgery, Anesthesiology
and Critical Care
University of Pennsylvania
Philadelphia, PA
Geoffrey T. Manley, M.D., Ph.D.
Professor of Neurosurgery
University of California, San Francisco
San Francisco, CA
Assistant Professor of Medicine
Medical University of South Carolina
Charleston, SC
Andrew I. R. Mass, M.D., Ph.D.
University Hospital of Antwerp
Antwerp, Belgium
Richard Moberg
President
Moberg Research
Ambler, PA
Associate Professor of Clinical Neurology
University of Miami
Miami, FL
DaiWai Olson, Ph.D., R.N.
Assistant Professor of Medicine
Duke University
Durham, NC
Yuko Y. Palesch, Ph.D.
Professor of Biostatistics, Bioinformatics and Epidemiology
Medical University of South Carolina
Charleston, SC
Soojin Park, M.D.
Assistant Professor of Neurology
University of Pennsylvania
Philadelphia, PA
Professor of Neurosurgery
Baylor College of Medicine
Houston, TX
Stelios Smirnakis, M.D., Ph.D.
Assistant Professor of Neurology and Neuroscience
Baylor College of Medicine
Houston, TX
Michael J. Souter, M.D.
Professor of Anesthesiology and Pain Medicine
University of Washington
Seattle, WA
Jose I. Suarez, M.D.
Professor of Neurology
Baylor College of Medicine
Houston, TX
Associate Professor of Neurology
University of Southern California
Los Angeles, CA
Christine Wijman, M.D., Ph.D.
Associate Professor of Neurology and Neurological Sciences
Stanford University
Palo Alto, CA
Professor of Neurosurgery
University of New Mexico
Albuquerque, NM
Assistant Professor of Clinical Neurosciences
University of Calgary
Alberta, Canada
Conference Schedule
Friday, May 18, 2012
6:00 p.m.
6:30
9:00
Registration
Welcoming Dinner and Reception
Opening Remarks
Jose I. Suarez, M.D.
NINDS Representative
Baylor College of Medicine and St. Luke's Episcopal Hospital Representative
Session Ends
Saturday, May 19, 2012
7:30 a.m.
8:00
8:30
9:00
9:30
9:45
10:15
10:45
11:15
11:45
12:00 Noon
1:00
1:30
2:00
2:30
3:00
3:15
3:30
4:00
4:30
5:00
5:30
5:45
6:00
7:00
7:15
9:00
Registration
Breakfast
History and Goals of the Meeting
Jose I. Suarez, M.D.
Multifaceted Therapeutic Bundles in Neurocritical Care: A New Approach
W. Andrew Kofke, M.D.
Coffee Break
Global Monitoring in the Neurocritical Care Unit ^
Moderator: Dai Wai Olson, Ph.D., R.N.
Intracranial Pressure Monitoring
Kristine O'Phelan, M.D.
Electrophysiology: EEG and Evoked Potentials
Puneet Gupta, M.D., M.S.E.
MRI Techniques
Stelios Smirnakis, M.D., Ph.D.
CT Scanning
Howard Yonas, M.D.
Questions and Comments
Lunch Break
Regional Brain Monitoring in the Neurocritical Care Unit ^
Moderator: Christine Wijman, M.D., Ph.D.
Microdialysis
Kristine O'Phelan, M.D.
Brain Tissue Oxygenation
Peter D. LeRoux, M.D.
Regional CBF
Peter J. Kirkpatrick
CBF Monitoring
Michael Diringer, M.D.
Questions and Comments
Coffee Break
Data Collection and Interpretation ^
Moderator: Peter D. Leroux, M.D.
Standardization of Data Acquisition
Giuseppe Citerio, M.D.
Data Display and Visualization
Soojin Park, M.D.
Data Analysis and Interpretation
Geoffrey T. Manley, M.D., Ph.D.
Integrating Multiple Monitors in a User-Friendly Format
Richard Moberg
Questions and Comments
Coffee Break
Integrating Biomarkers and Multimodality Monitoring
Robert S. B. Clark, M.D.
Questions and Comments
Dinner
Session Ends
Sunday, May 20, 2012
7:30 a.m.
8:00
8:30
9:00
9:30
10:00
10:30
10:45
11:00
11:30
11:45
12:15 p.m.
12:45
1:00
1:30
Registration
Continental Breakfast
Conventional Clinical Trial Design of Multimodality Monitoring ^
Moderator: Romergryko Geocadin, M.D.
Sample Size Calculations
Yuko Palesch, Ph.D.
Can We Demonstrate the Efficacy of Monitoring?
David Zygun, M.D.
Efficacy Endpoints
Claude Hemphill III, M.D.
Patient Selection and Recruitment
Claudia S. Robertson, M.D.
Questions and Comments
Coffee Break
Alternative Clinical Trial Design ^
Moderator: Gene Sung, M.D., M.P.H.
Comparative Effectiveness Research
Andrew I. R. Mass, M.D., Ph.D.
Should we use Sliding Dichotomy?
Renee H. Martin, Ph.D.
What Surrogate End-Points are Worth Investigating?
Michael J. Souter, M.D.
What Should We Learn from the Failure of Phase III Clinical Trials in the Neurocritically ill?
Randall Chestnut, M.D.
Questions and Comments
Concluding Remarks
Jose I. Suarez, M.D. and All Attendees
Conference Adjourns
^ Presenters and moderators will have a 1-hour breakout session to refine summary statements
and ideas following their presentation.
Onsite Conference Contact
Jose I. Suarez, M.D.
Phone: 713-319-4454
Email:
Theresa Kukic
Phone: 412-207-9735
Email:
Continuing Medical Education
St. Luke's Episcopal Hospital is accredited by the Texas Medical Association to provide continuing medical education for physicians. St. Luke's designates this educational activity for a maximum of 11.75 AMA PRA Category 1 Credit(s)™. We also have made arrangements to provide an equal number of CE Credits for nurses. Physicians and nurses should only claim credit commensurate with the extent of their participation in the activity.