Neurology: Case of the Month

Test Yourself — Patient 7

Progressive Supranuclear Palsy (PSP)

  1. All of the following statements are true regarding PSP EXCEPT:
    • [ A ] mean survival is 5.9 years
    • [ B ] mean age of onset is 30 to 35
    • [ C ] there is no gender preferance
    • [ D ] prevalence is approximately 1.39 per 100,000
  2. Criteria for a diagnosis of PSP, according to NINDS, includes all of the following EXCEPT:
    • [ A ] progressive course with onset at or over the age of 40
    • [ B ] bilateral supranuclear disorder of ocular motility
    • [ C ] axial rigidity and bradykinesia
    • [ D ] cerebellar symptoms
  3. All of the following eye findings would be characteristic for a patient with PSP EXCEPT:
    • [ A ] disturbance in smooth pursuit eye movement
    • [ B ] on horizontal gaze, nystagmus of the abducting eye and paresis of the adducting eye
    • [ C ] dysfunction of downward gaze and eventually upward gaze
    • [ D ] decreased blinking and suppression of blinking to bright light
  4. The following statement is true regarding PSP:
    • [ A ] The pathology is characterized by neurofibrillary tangles.
    • [ B ] Levodopa is an effective treatment for axial dystonia and ophthalmoplegia seen in PSP.
    • [ C ] CT scan usually reveals reduction in the AP diameter of the medulla and upper cervical cord.
    • [ D ] Sensory deficits and aphasia are common symptoms.
  5. PSP may cause eye movement dysfunction of
    • [ A ] saccades and pursuit
    • [ B ] vertical gaze
    • [ C ] vestibuloocular reflex
    • [ D ] all of the above

 

Email comments: