Test Yourself — Patient 48

Systemic Lupus Erythematosus

  1. Neuropsychiatric manifestations of lupus are uncommon.
    • [ A ] True
    • [ B ] False
  2. A single diagnostic test with high specificity (e.g., serum antibody to double-stranded DNA) is sufficient to establish a diagnosis of systemic lupus erythematosus.
    • [ A ] True
    • [ B ] False
  3. Which of the following statements is TRUE?
    • [ A ] CNS manifestations of lupus nearly always result from local complications of aseptic meningitis or small-vessel vasculitis.
    • [ B ] The most common manifestation of CNS lupus is seizures.
    • [ C ] The appearance of confluent white matter abnormalities and encephalopathy in a patient with systemic lupus and renal hypertension confirms a diagnosis of active neuropsychiatric lupus.
    • [ D ] Typical migraine headache is uncommon in CNS lupus.
    • [ E ] CNS manifestations of lupus are often reversible.
  4. Which neuroimaging test is most sensitive in the detection of CNS lupus?
    • [ A ] Contrast-enhanced CT
    • [ B ] MRI
    • [ C ] SPECT
    • [ D ] Dye angiography
  5. Which of the following clinical features is considered a common manifestation of the associated disease process?
    • [ A ] Migraine headaches preceding the onset of CADASIL-related dementia
    • [ B ] Seizures as an initial presentation of multiple sclerosis
    • [ C ] Diffuse white matter changes in CNS tuberculosis
    • [ D ] Cranial nerve deficits in patients with sickle cell trait
    • [ E ] More than one of the above

 

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