Neurology: Case of the Month

Test Yourself — Patient 38

Hemangioblastoma

1. With which syndrome are hemangioblastomas most frequently associated?
   • [ A ] Kearns-Sayre syndrome
   • [ B ] Von Hippel-Lindau syndrome
   • [ C ] Von Recklinghausen's disease
   • [ D ] Vogt-Koyanagi-Harada syndrome
   • [ E ] Laurence-Moon-Bardet-Biedl syndrome
2. Expression of what type of hormone or signaling molecule is often associated with hemangioblastoma growth?
   • [ A ] Vascular endothelial growth factor
   • [ B ] Epithelial membrane antigen
   • [ C ] Synaptophysin
   • [ D ] Insulin-like growth factor
   • [ E ] Angiotensin
3. On which chromosome has the von Hippel-Lindau gene been localized?
   • [ A ] 4
   • [ B ] 7
   • [ C ] 3
   • [ D ] 11
   • [ E ] 22
4. In which part of the CNS are hemangioblastomas found most often?
   • [ A ] Frontal lobes
   • [ B ] Cerebellum
   • [ C ] Occipital lobes
   • [ D ] Temporal lobes
   • [ E ] Brainstem
5. In which of the following organs do tumors most commonly occur in association with hemangioblastomas as part of the von Hippel-Lindau syndrome?
   • [ A ] Heart
   • [ B ] Lung
   • [ C ] Pancreas
   • [ D ] Kidney
   • [ E ] Bladder

 

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