Intracytoplasmic sperm injection, or ISCI, is a modification of the IVF procedure, using the same methods, except that instead of simply incubating the sperm and egg together in a Petri dish, the egg is stabilized under a special microscope with a micro-suction instrument while a very fine pipette is used to inject a selected sperm into the egg.
This sperm injection technique allows couples to overcome many barriers to sperm count, motility, morphology and degree of sperm maturity. ICSI has made it possible for couples, who in the past would have been unable to achieve pregnancies, to bear their own biologic children.