Baylor College of Medicine

Merck Major Depressive Disorder Study (H-49080)



Depression is a common mental illness that affects quality of life. Many people who have depression still experience symptoms despite being on treatments.

This study will test a study drug to see if it could help reduce symptoms of depression. 

You may be able to take part in this study if you are 18-65 years old and:

  • Have moderate to severe major depressive disorder
  • Have had an inadequate response to at least two but no more than four antidepressant medications.
  • Are on a stable course of antidepressant therapy and agree to continue this during the study
  • If female, your study doctor may have additional questions regarding your reproductive potential. 

All inquiries are confidential. Contact us at (713) 689-9856 or

IRB: H-49080




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