Study on efficacy, safety of Sodium Polystyrene Sulfonate (H-40679)

Background: Sodium polystyrene sulfonate (SPS) is a potassium binder commonly used in acute and subacute settings to treat hyperkalemia. However, its efficacy has only been reviewed in a limited number of studies which show that it lowers potassium in 1 to 7 days. Moreover, efficacy and safety studies in the ED are lacking.

Purpose: Evaluate the efficacy and safety of SPS use in first 12 hours

Project status: ready for enrollment

Coordinator Role: screen, consent, enroll and collect data.

Open to students: Yes