Gene regulation research in the Cancer & Cell Biology Program is focused on mechanisms that act to induce or repress the expression of genes, epigenetic changes in chromatin, binding of proteins to specific DNA elements to regulate transcription and mechanisms that modulate translation of mRNA.

A-G: Profiles of Faculty Working on Gene Regulation

Andre Catic, M.D., Ph.D.

Assistant Professor & CPRIT Scholar in Cancer Research

Phone

  • (713) 798-1567

We study protein quality control mechanisms and their involvement in gene regulation, metabolism, and aging.

Eric C Chang, Ph.D.

Associate Professor

Phone

  • (713) 798-3519

Xi Chen, Ph.D.

Assistant Professor & CPRIT Scholar

ER protein quality control; Stem Cell Maintenance; Endoplasmic Reticulum-Associated Degradation; Unfolded Protein Response; Tumor Microenvironment; Therapy resistance

Chonghui Cheng, M.D., Ph.D.

Associate Professor

RNA; Alternative splicing; Breast Cancer Metastasis; Clinical Applications

Orla M Conneely, Ph.D.

Professor

Dean Edwards, Ph.D.

Professor

Phone

  • (713) 798-2326

Tony Eissa, M.D.

Professor

Phone

  • (713) 798-3190

Regulation of Autophagy in Innate Immunity; Cellular Regulation of Nitric Oxide Synthesis in Inflammation; Cellular regulation of misfolded proteins

Xin-Hua Feng, Ph.D.

Professor of Surgery

Phone

  • (713) 798-4756

Embryonic stem cells; Serine/threonine phosphatases; SMAD; SUMOylation; TGF-ß/BMP; Ubiquitination

Josephine Chu Ferreon, Ph.D.

Assistant Professor

Phone

  • (713) 798-1756

NMR Spectroscopy; Stem Cell Biology; Intrinsically Disordered Proteins; Protein Structure and Function; Post-Translational Modifications

Charles E Foulds, Ph.D.

Assistant Professor

Loning Fu, Ph.D.

Associate Professor

Phone

  • (713) 798-0342

Margaret A Goodell, Ph.D.

Professor

Phone

  • (713) 798-1265

Murine and human hematopoietic stem cells; Genetic and epigenetic regulation and development.

Daniel A Gorelick, Ph.D.

Assistant Professor

Cell signaling; Environmental influence on organ formation & function; Zebrafish genetics

H-M: Profiles of Faculty Working on Gene Regulation

Darryl L. Hadsell, Ph.D.

Associate Professor

Phone

  • (713) 798-7043

Lactation Biology, Mammalian Genomics

Sean M. Hartig, Ph.D.

Assistant Professor

Cellular Mechanisms of Obesity and Diabetes

Kendal D Hirschi, Ph.D.

Professor

Phone

  • (713) 798-7011

Nutritional improvement of agriculturally important crops

H. Courtney Hodges, Ph.D.

Assistant Professor

Epigenomics; Super-resolution imaging; Chromatin and epigenetics; Cancer biology

Deborah L Johnson, Ph.D.

Professor

Phone

  • (713) 798-4032

Transcription Factors; Oncogenic Transformation; PTEN; TATA-binding protein; Maf1; Graduate Student Education

Daniel Lacorazza, Ph.D.

Associate Professor

Phone

  • (832) 824-5103

Development and differentiation of the immune system; Transcriptional regulation of blood formation; Pathobiology and treatment of leukemia…

Rainer Lanz, Ph.D.

Associate Professor

Michael T. Lewis, Ph.D., B.S.

Professor

Phone

  • (713) 798-3296

Yi Li, Ph.D., M.S., B.S.

Professor

Phone

  • (713) 798-3963

Breast cancer initiation and progression; Wnt signaling and cancer stem cells; Breast Cancer Prevention; JAK-STAT signaling in breast cancer

Weei-Chin Lin, M.D., Ph.D.

Professor of Medicine

Phone

  • (713) 798-2641

Cell cycle regulation; Development of cancer therapeutics; Clinical hematology

David Lonard, Ph.D.

Associate Professor

Research interests

John P Lydon, Ph.D.

Associate Professor

Steroid receptor and coregulator control of normal and abnormal functions of the uterus and mammary gland.

Michael A Mancini, Ph.D.

Single cell analysis of gene regulation

Shailaja K Mani, Ph.D.

Associate Professor

Susan Jean Marriott, Ph.D.

Professor

Phone

  • (713) 798-4440

Viral transformation and transcription control

Nicholas Mitsiades, M.D.

Associate Professor

Phone

  • (713) 798-5293

N-S: Profiles of Faculty Working on Gene Regulation

Daisuke Nakada, Ph.D.

Associate Professor

Phone

  • (713) 798-1175

Normal and malignant stem cells in the blood system

Joel Neilson, Ph.D.

Associate Professor

Phone

  • (713) 798-8851

Molecular Biology and Genetics; Cell and Developmental Biology; Post-Transcriptional Regulation of Gene Expression; Human Disease

Bert W O'Malley, M.D.

Chair/Professor

Phone

  • (713) 798-6205

Hormone action; Coactivator function; Eukaryotic gene expression; Gene therapy; Nanotechnology

Paul Overbeek, Ph.D.

Professor

Phone

  • (713) 798-6421

Stephanie A Pangas, Ph.D.

Roger Rossen Endowed Professorship of Reproductive Pathology andAssociate Professor

Phone

  • (713) 798-5898

Reproductive Biology; Reproductive Cancers

Frederick A Pereira, Ph.D.

Associate Professor

Phone

  • (713) 798-6933

Signaling pathways in auditory development, aging and cancer prevention; Circadian Rhythms; Hearing and Balance disorders; Auditory neuropathy…

Joanne S Richards, Ph.D.

Professor

Phone

  • (713) 798-6238

David R Rowley, Ph.D.

Professor

Phone

  • (713) 798-6220

Mechanisms of reactive stroma in cancer progression.

Ergun Sahin, M.D., Ph.D.

Assistant Professor

Phone

  • (713) 798-6685

Telomere function, aging and cancer biology

Noah Freeman Shroyer, Ph.D.

Associate Professor

Phone

  • (713) 798-8693

Mechanisms that control intestinal development and homeostasis; Human Enteroids

Carolyn L Smith, Ph.D.

Dean

Phone

  • (713) 798-7640

Negative regulation of estrogen receptor function; ER and coactivator interactions; Breast & Bladder Cancer; Graduate Education

Zhou Songyang, Ph.D.

Professor

Phone

  • (713) 798-5220

Arun Sreekumar, Ph.D.

Professor

Phone

  • (713) 798-3305

Cancer Biology; Drug Resistance Mechanisms; Metabolism; Signal Transduction

Fabio Stossi, Ph.D.

Associate Professor

T-Z: Profiles of Faculty Working on Gene Regulation

Ming-Jer Tsai, Ph.D.

Dist Serv Prof

Phone

  • (713) 798-6253

Sophia Y Tsai, Ph.D.

Professor

Phone

  • (713) 798-6251

Koen J. T. Venken, Ph.D.

Assistant Professor

Phone

  • (713) 798-3698

Human Disease Modeling; Genome Engineering; Genetic Manipulation; Method Development; Technology Development; Cellular and organismal model systems…

Nancy L Weigel, Ph.D.

Professor

Phone

  • (713) 798-6234

Coactivators and androgen receptors in prostate cancer; vitamin D receptor target genes.

Trey Westbrook, Ph.D.

Professor

Phone

  • (713) 798-5364

Jianming Xu, Ph.D.

Professor

Phone

  • (713) 798-6199

Gene networks & signaling pathways that regulate steroid hormone-promoted cancers

Laising Yen, Ph.D.

Associate Professor

Phone

  • (713) 798-1180

Investigating RNA mutational events in cancer; Engineering RNA-based switches for gene regulation & biosensor

Robert Brian York

Associate Professor

Phone

  • (713) 798-4178

Liver Cancer; Hepatic Metabolism; Inflammation; Calcium Signaling

Li-Yuan Yu-Lee, Ph.D.

Professor

Phone

  • (713) 798-4770

Immune and inflammatory responses and regulation; Mitotic kinases in cell cycle regulation; Cytokinesis and aneuploidy; Cell migration and metastasis

Jihye Yun, Ph.D.

Assistant Professor

Phone

  • (713) 798-3632

Understanding the role of dietary factors in colorectal cancer pathogenesis (Key words: Cancer Metabolism, Microbiome, Genetic mutations, Mouse models, Organoids)

Jason T. Yustein, M.D.-Ph.D.

E. Lynn Zechiedrich, Ph.D.

Kyle and Josephine Morrow Chair in Molecular Virology and Microbiology

Phone

  • (713) 798-5126

DNA supercoiling, DNA topoisomerases, antibiotic resistance, gene therapy

Zheng Zhou, Ph.D.

Professor

Phone

  • (713) 798-6489

Molecular genetic studies of clearance of apoptotic cells in C. elegans

Chenghang (Chuck) Zong, Ph.D.

Assistant Professor

Phone

  • (713) 798-6102

Single cell analyses, tumorigenesis, genome instability