Researchers focused on cancer genetics and genomics in the Cancer & Cell Biology Program investigate genomic changes in tumors, gene mutations and pathways and development of novel therapeutics.

A-K: Profiles of Faculty Working on Cancer Genetics and Genomics

Alison Ann Bertuch, M.D., Ph.D.

Associate Professor

Phone

  • (832) 824-4579

Dyskeratosis congenita; Mechanisms of bone marrow failure…

Andre Catic, M.D., Ph.D.

Assistant Professor & CPRIT Scholar in Cancer Research

Phone

  • (713) 798-1567

We study protein quality control mechanisms and their involvement in gene regulation, metabolism, and aging.

Pui-Kwong Chan, Ph.D.

Professor

Phone

  • (713) 798-7902

Eric C Chang, Ph.D.

Associate Professor

Phone

  • (713) 798-3519

Xi Chen, Ph.D.

Assistant Professor & CPRIT Scholar

ER protein quality control; Stem Cell Maintenance; Endoplasmic Reticulum-Associated Degradation; Unfolded Protein Response; Tumor Microenvironment; Therapy resistance

Chonghui Cheng, M.D., Ph.D.

Associate Professor

RNA; Alternative splicing; Breast Cancer Metastasis; Clinical Applications

Matthew J. Ellis, MB, BChir, BSc., PhD, FRCP

Professor / Director

Phone

  • (713) 798-1999

Breast Cancer Oncology; Breast Cancer Genomics; Metastatic Breast Cancer; Clinical Trials

Xin-Hua Feng, Ph.D.

Professor of Surgery

Phone

  • (713) 798-4756

Embryonic stem cells; Serine/threonine phosphatases; SMAD; SUMOylation; TGF-ß/BMP; Ubiquitination

Josephine Chu Ferreon, Ph.D.

Assistant Professor

Phone

  • (713) 798-1756

NMR Spectroscopy; Stem Cell Biology; Intrinsically Disordered Proteins; Protein Structure and Function; Post-Translational Modifications

Suzanne A W Fuqua, Ph.D.

Professor

Phone

  • (713) 798-1671

Breast cancer; Hormone receptors, hormone responsiveness, gene expression profiling, mutant ER, metastasis, predictive markers

Margaret A Goodell, Ph.D.

Professor

Phone

  • (713) 798-1265

Murine and human hematopoietic stem cells; Genetic and epigenetic regulation and development.

H. Courtney Hodges, Ph.D.

Assistant Professor

Epigenomics; Super-resolution imaging; Chromatin and epigenetics; Cancer biology

Grzegorz Ira, Ph.D.

Professor

Phone

  • (713) 798-1017

Genome Instability; Molecular mechanisms and regulation of DNA recombination

Deborah L Johnson, Ph.D.

Professor

Phone

  • (713) 798-4032

Transcription Factors; Oncogenic Transformation; PTEN; TATA-binding protein; Maf1; Graduate Student Education

L-R: Profiles of Faculty Working on Cancer Genetics and Genomics

Daniel Lacorazza, Ph.D.

Associate Professor

Phone

  • (832) 824-5103

Development and differentiation of the immune system; Transcriptional regulation of blood formation; Pathobiology and treatment of leukemia…

Rainer Lanz, Ph.D.

Associate Professor

Michael T. Lewis, Ph.D., B.S.

Professor

Phone

  • (713) 798-3296

Yi Li, Ph.D., M.S., B.S.

Professor

Phone

  • (713) 798-3963

Breast cancer initiation and progression; Wnt signaling and cancer stem cells; Breast Cancer Prevention; JAK-STAT signaling in breast cancer

David Lonard, Ph.D.

Associate Professor

Research interests

Susan Jean Marriott, Ph.D.

Professor

Phone

  • (713) 798-4440

Viral transformation and transcription control

Nicholas Mitsiades, M.D.

Associate Professor

Phone

  • (713) 798-5293

Joel Neilson, Ph.D.

Associate Professor

Phone

  • (713) 798-8851

Molecular Biology and Genetics; Cell and Developmental Biology; Post-Transcriptional Regulation of Gene Expression; Human Disease

Bert W O'Malley, M.D.

Chair/Professor

Phone

  • (713) 798-6205

Hormone action; Coactivator function; Eukaryotic gene expression; Gene therapy; Nanotechnology

C Kent Osborne, M.D.

Director

Phone

  • (713) 798-1999

Diagnosis and treatment of breast cancer; Biology of breast cancer; Resistance to ER and HER2-targeted therapies in breast cancer…

Paul Overbeek, Ph.D.

Professor

Phone

  • (713) 798-6421

Sharon E Plon, M.D., Ph.D.

Professor

Phone

  • (832) 832-4539

Cancer predisposition syndromes

Jeffrey M Rosen, Ph.D.

Professor

Phone

  • (713) 798-6210

Developmental and hormonal regulation of mammary gland gene expression and breast cancer

S-Z: Profiles of Faculty Working on Cancer Genetics and Genomics

Noah Freeman Shroyer, Ph.D.

Associate Professor

Phone

  • (713) 798-8693

Mechanisms that control intestinal development and homeostasis; Human Enteroids

Richard N Sifers, Ph.D.

Professor

Phone

  • (713) 798-3169

Glycobiology; Secretory Pathway; Protein Biosynthetic Quality Control; Conformational Disease; Alpha1-antitrypsin Deficiency; Disease Modifiers…

Zhou Songyang, Ph.D.

Professor

Phone

  • (713) 798-5220

Ming-Jer Tsai, Ph.D.

Dist Serv Prof

Phone

  • (713) 798-6253

Sophia Y Tsai, Ph.D.

Professor

Phone

  • (713) 798-6251

Koen J. T. Venken, Ph.D.

Assistant Professor

Phone

  • (713) 798-3698

Human Disease Modeling; Genome Engineering; Genetic Manipulation; Method Development; Technology Development; Cellular and organismal model systems…

Cheryl Walker, Ph.D.

Director

Phone

  • (713) 798-8219

Nancy L Weigel, Ph.D.

Professor

Phone

  • (713) 798-6234

Coactivators and androgen receptors in prostate cancer; vitamin D receptor target genes.

Trey Westbrook, Ph.D.

Professor

Phone

  • (713) 798-5364

Jianming Xu, Ph.D.

Professor

Phone

  • (713) 798-6199

Gene networks & signaling pathways that regulate steroid hormone-promoted cancers

Laising Yen, Ph.D.

Associate Professor

Phone

  • (713) 798-1180

Investigating RNA mutational events in cancer; Engineering RNA-based switches for gene regulation & biosensor

Li-Yuan Yu-Lee, Ph.D.

Professor

Phone

  • (713) 798-4770

Immune and inflammatory responses and regulation; Mitotic kinases in cell cycle regulation; Cytokinesis and aneuploidy; Cell migration and metastasis

Jihye Yun, Ph.D.

Assistant Professor

Phone

  • (713) 798-3632

Understanding the role of dietary factors in colorectal cancer pathogenesis (Key words: Cancer Metabolism, Microbiome, Genetic mutations, Mouse models, Organoids)

E. Lynn Zechiedrich, Ph.D.

Kyle and Josephine Morrow Chair in Molecular Virology and Microbiology

Phone

  • (713) 798-5126

DNA supercoiling, DNA topoisomerases, antibiotic resistance, gene therapy

Pumin Zhang, Ph.D.

Professor

Phone

  • (713) 798-1866

Cell and Developmental Biology; Human Disease; Molecular Biology and Genetics

Xiang Zhang, Ph.D

Professor

Chenghang (Chuck) Zong, Ph.D.

Assistant Professor

Phone

  • (713) 798-6102

Single cell analyses, tumorigenesis, genome instability