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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Pumin Zhang, Ph.D.

Pumin Zhang

Associate Professor
Department of Molecular Physiology and Biophysics

Phone: 713-798-1866
Fax: 713-798-3475


  • Ph.D., University of Wisconsin, Madison, WI
  • Postdoctoral, Baylor College of Medicine, Houston, TX

Research Interests

  • Cell cycle regulation
  • Myogenesis
  • Lens development
  • Rhabdomyosarcoma

Selected Publications

  • Li M, York JP, Zhang P. Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos. Mol Cell Biol. 2007. 27:3481-8.
  • Georgia S, Li M, Zhang P, Bhushan A. p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol. 2006. 298:22-31.
  • Peng X, York JP, Zhang P. A transgenic approach for RNA interference-based genetic screening in mice. Proc Natl Acad Sci U S A. 2006. 103:2252-6.
  • Huang X, Hatcher R, York JP, Zhang P. Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells. Mol Biol Cell. 2005. 16:4725-32.
  • Huang X, Tran T, Zhang L, Hatcher R, Zhang P. DNA damage induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint. Proc Natl Acad Sci U S A. 2005. 102:1065-70.
  • Delgado I, Huang X, Jones S, Zhang L, Hatcher L, Gao B, Zhang P. (2003). Dynamic gene expression during the onset of myoblast differentiation in vitro. Genomics. 2003. 82:109-21.
  • Zhang P, Liu M, Elledge S. Towards genetic genome projects: genomic library screening and gene targeting vector construction in a single step. Nat Genet. 2002. 30:31-9.

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