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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Li-Yuan Yu-Lee, Ph.D.

Department of Medicine - Immunology, Allergy
and Rheumatology
Department of Pathology and Immunology

Phone: 713-798-4770
Fax: 713-798-2050


  • Ph.D., Columbia University
  • Postdoctoral, Baylor College of Medicine

Research Interests

  • Immune and inflammatory responses and regulation
  • Motitic kinases in cell cycle regulation
  • Cytokinesis and aneuploidy
  • Cell migration and metastasis

Selected Publications

  • Lee SH, Nishino M, Mazumdar T, Garcia GE, Galfione M, Lee FL, Lee CL, Liang A, Kim J, Feng L, Eissa NT, Lin SH, Yu-Lee LY. 16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory factor-1 pathway. Cancer Res. 2005. 65:7984-92.
  • Lin SH, Nishino M, Luo W, Aumais JP, Galfione M, Kuang J, Yu-Lee LY. Inhibition of prostate tumor growth by overexpression of NudC, a microtubule motor-associated protein. Oncogene. 2004. 23(14):2499-506.
  • Aumais JP, Williams SN, Luo W, Nishino M, Caldwell KA, Caldwell GA, Lin SH, Yu-Lee LY. Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. J Cell Sci. 2003. 116(Pt 10):1991-2003.
  • Zhou T-H, Aumais JP, Liu X, Yu-Lee LY, Erikson RL. A role for Plk1 phosphorylation of NudC in cytokinesis. Dev Cell. 2003. 5:127-38.
  • Yu-Lee LY. Prolactin modulation of immune and inflammatory responses. Rec Prog Hormone Res. 2002. 57:435-55.
  • Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY. NudC associates with Lis1 and the dynein motor at the leading pole of neurons. J Neurosci. 2001. 21(24):RC187.

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