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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Joseph F. Petrosino, Ph.D.

Joseph F. Petrosino

Assistant Professor
Department of Molecular Virology and Microbiology
Human Genome Sequencing Center

Phone: 713-798-7912
Fax: 713-798-7375


  • Ph.D., Baylor College of Medicine, Houston, TX
  • Postdoctoral, Baylor College of Medicine, Houston, TX

Research Interests

  • Functional genomics of infectious disease

Selected Publications

  • Karpathy SE, Qin X, Gioia J, Jiang H, Liu Y, Petrosino JF, Yerrapragada S, Fox GE, Haake SK, Weinstock GM, Highlander SK. Genome sequence of Fusobacterium nucleatum subspecies polymorphum – a genetically tractable fusobacterium. PLoS ONE. 2007. 2:e659.
  • Petrosino JF, Xiang Q, Karpathy SE, Jiang H, Yerrapragada S, Liu Y, Gioia J, Hemphill L, Gonzalez A, Raghavan TM, Uzman A, Fox GE, Highlander S, Reichard M, Morton RJ, Clinkenbeard KD, Weinstock GM. Chromosome rearrangement and diversification of Francisella tularensis revealed by the type B (OSU18) genome sequence. J Bacteriol. 2006. 188:6977-85.
  • Hastings PJ, Slack A, Petrosino JF, Rosenberg SM. Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms. PLoS Biol. 2004. 2:e399.
  • Petrosino JF, Pendleton AR, Weiner JH, Rosenberg SM. Chromosomal system for studying AmpC-mediated beta-lactam resistance mutation in Escherichia coli. Antimicrob Agents Chemother. 2002. 46:1535-9.
  • Petrosino JF, Baker M, Palzkill T. Susceptibility of beta-lactamase to core amino acid substitutions. Protein Eng. 1999. 12:761-9.
  • Petrosino JF, Palzkill T. Systematic mutagenesis of the active site omega loop of TEM-1 beta-lactamase. J Bacteriol. 1996. 178:1821-8.

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