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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Richard L. Hurwitz, M.D.

Richard L. Hurwitz

Associate Professor
Department of Pediatrics - Hematology and Oncology
Director od Retinoblastoma Center, Texas Children's Cancer Center and Hematology Service

Phone: 832-824-4259
Fax: 832-825-4846
E-mail: rhurwitz@bcm.edu

Education

  • M.D., Albany Medical College
  • Fellowship, University of Minnesota Hospitals
  • Fellowship, University of Washington

Research Interests

  • Gene therapy
  • Retinoblastoma
  • Retinal degeneration

Clinical Focus

  • Pediatric hematology-oncology
  • Inherited ocular disorders

Selected Publications

  • Chaudhuri S-R, Mallam JN, Chévez-Barrios P, Wadhwa L, Ng P, Hurwitz MY, Hurwitz RL. Modulation of adenoviral transduction in vitro and in vivo by hyaluronan and its receptor CD44. Molecular Therapy. 2007. 15:566-70.
  • Chong E-M, Coffee RE, Chintagumpala M, Hurwitz RL, Hurwitz MY, Chévez-Barrios P. Extensively necrotic retinoblastoma is associated with high risk prognostic factors. Arch Path and Lab Med. 2006.130:1669-72.
  • Chévez-Barrios P, Chintagumpala M, Mieler W, Paysse E, Boniuk M, Kozinetz C, Hurwitz MY, Hurwitz RL. Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir. J Clinical Oncology. 2005. 23:7929-35.
  • Hurwitz RL, Shields CL, Shields JA, Chévez-Barrios P, Hurwitz MY, Chintagumpala MM. Retinoblastoma, in PA Pizzo and DG Poplack eds. Principles and practice of pediatric oncology (4th edition). Lippincott-Williams & Wilkins, Philadelphia, 2005, pp 861-82.
  • Mallam J, Hurwitz M., Mahoney T, Chévez-Barrios P, Hurwitz R.L. Efficient gene transfer into retinal cells using adenoviral vectors: Dependence on receptor expression. Invest Ophthalmol Vis Sci. 2004. 45:1680-7.
  • Suber ML, Hurwitz MY, Chévez-Barrios P, Hurwitz RL. Immune consequences of intraocular administration of modified adenoviral vectors. Human Gene Therapy. 2001. 12:833-8.
  • Chévez-Barrios P, Hurwitz MY, Louie K, Marcus KT, Holcombe VN, Schafer P, Aguilar-Cordova E, Hurwitz RL. Metastatic and non-metastatic models of retinoblastoma. American Journal of Pathology. 2000. 157:1405-12.

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