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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Matthew H. Wilson, M.D., Ph.D.

Matthew H. Wilson, M.D., Ph.D.Assistant Professor
Department of Medicine - Nephrology

Phone: 713-798-1303
Fax: 713-798-5010


  • M.D., Ph.D., Vanderbilt University, Nashville, TN
  • Residency, Internal Medicine, Vanderbilt University, Nashville, TN
  • Fellowship, Nephrology/Genetic Medicine, Vanderbilt University, Nashville, TN

Research Interests

  • Transposons and gene therapy for renal diseases

Selected Publications

  • Wang J, Wang Y, Long J, Chang B, Wilson MH, Overbeek P, Danesh FR. A tamoxifen-inducible podocyte-specific iCre recombinases transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis. In press.
  • Kahlig KM, Saridey SK, Kaja A, Daniels MA, George AL Jr, Wilson MH. Multiplexed transposon-mediated stable gene transfer in human cells. Proc Natl Acad Sci U S A. 2010. 107(4):1343-8.
  • Manuri PV, Wilson MH, Maiti SN, Mi T, Singh H, Olivares S, Dawson MJ, Huls H, Lee DA, Rao PH, Kaminski JM, Nakazawa Y, Gottschalk S, Kebriaei P, Shpall EJ, Champlin RE, Cooper LJ. PiggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies. Hum Gene Ther. 2010. 21(4):427-37.
  • Galvan DL, Nakazawa Y, Kaja A, Kettlun C, Cooper LJ, Rooney CM, Wilson MH. Genome-wide mapping of PiggyBac transposon integrations in primary human T cells. J Immunother. 2009. 32(8):837-44.
  • Nakazawa Y, Huye LE, Dotti G, Foster AE, Vera JF, Manuri PR, June CH, Rooney CM, Wilson MH. Optimization of the PiggyBac transposon system for the sustained genetic modification of human T lymphocytes. J Immunother. 2009. 32(8):826-36.
  • Saridey SK, Liu L, Doherty JE, Kaja A, Galvan DL, Fletcher BS, Wilson MH. PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer. Mol Ther. 2009. 17(12):2115-20.
  • Wilson MH, Coates CJ, George AL Jr. PiggyBac transposon-mediated gene transfer in human cells. Mol Ther. 2007. 15(1):139-45.

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