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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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N. Tony Eissa, M.D.

N. Tony Eissa

Professor and Chief of Research
Department of Medicine - Pulmonary, Critical Care, and Sleep Medicine
Department of Molecular and Cellular Biology
Department of Pathology and Immunology

Phone: 713-798-3657
Fax: 713-798-3619
E-mail: teissa@bcm.edu
Lab: Eissa Lab

Education

  • M.D., Tanta Faculty of Science, Tanta, Egypt
  • Internal Medicine,Cornell Medical Center
  • Critical Care Medicine Fellowship, Albert Einstein College of Medicine
  • Research Fellow, Critical Care Division, Albert Einstein College of Medicine
  • Postdoctoral Research Fellow, Meakins‑Christie Labs, McGill University
  • Clinical Pulmonary Fellow, Pulmonary Branch, NHLBI, NIH

Research Interests

  • Airway inflammation
  • iNOS
  • Ubiquitination
  • Mouse models of asthma

Clinical Focus

  • Asthma
  • Cystic fibrosis
  • Interstitial lung diseases
  • Alpha one antitrypsin deficiency

Selected Publications

  • Xu Y, Jagannath C, Liu X-D, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity. 2007. 27:135-44.
  • Kolodziejska KE, Burns AR, Moore RH, Stenoien DL, Eissa NT. Regulation of inducible nitric oxide synthase by aggresome formation. Proc Natl Acad Sci U S A. 2005. 102:4854-9.
  • Kolodziejski PJ, Koo J-S, Eissa NT. Regulation of inducible nitric oxide synthase by rapid cellular turnover and co-translational downregulation by dimerization inhibitors. Proc Natl Acad Sci U S A. 2004. 101:18141-6.
  • Kolodziejski PJ, Rashid MB, Eissa NT. Intracellular formation of novel “undisruptable” dimers of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 2003. 100:14263-8.
  • Kolodziejski PJ, Musial A, Koo J-S, Eissa NT. Ubiquitination of inducible nitric oxide synthase is required for its degradation. Proc Natl Acad Sci U S A. 2002. 99:12315-20.

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