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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Mariella De Biasi, Ph.D.

Mariella De Biasi

Associate Professor
Department of Neuroscience

Phone: 713-798-3618
Fax: 713-798-3946


  • Ph.D., University of Padova, Italy

Research Interests

  • Molecular basis of nicotine addiction
  • Mouse models

Clinical Focus

  • Neurological/psychiatric disorders

Selected Publications

  • Rezvani K, Teng Y, Shim D, De Biasi M. Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity. J Neurosci. 2007. 27(39):10508-19.
  • Zhou FM, Liang Y, Salas R, Zhang L, De Biasi M, Dani JA. Co-release of dopamine and serotonin from striatal dopamine terminals. Neuron. 2005. 46:65-74.
  • Salas R, Cook K, Bassetto L, De Biasi M. The a3 and 4 nicotinic acetylcholine receptor subunits are necessary for the behavioral effects of acute nicotine. Neuropharmacology. 2004. 47:401-7.
  • Salas R, Pieri F, De Biasi M. Decreased signs of nicotine withdrawal in mice null for the 4 nicotinic acetylcholine receptor subunit. J Neurosci. 2004. 24:10035-9.
  • De Biasi M, Dani JA. Stress hormone corticotropin-releasing factor enhances synaptic NMDA receptors on dopamine neurons. Neuron. 2003. 39:387-94.
  • Salas R, Orr-Urtreger A, Broide R, Paylor R, Beaudet AL, De Biasi M. The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo. Mol Pharmacol. 2003. 63:10059-66.
  • Salas R, Pieri F, Fung B, Beaudet AL, Dani JA, De Biasi M. Abnormal anxiety-like responses in 4 subunit nicotinic acetylcholine receptor mutant mice. J Neurosci. 2003. 23:6255-63.

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