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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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William Brownell, Ph.D.

William Brownell, Ph.D.

Department of Otolaryngology - Head and Neck Surgery

Phone: 713-798-8540
Fax: 713-798-8553


  • Ph.D., University of Chicago

Research Interests

  • Mechanics of hearing
  • Molecular basis of cochlear outer hair cell function

Selected Publications

  • Ermilov SA, Murdock DR, Qian F, Brownell WE, Anvari B. Studies of plasma membrane mechanics and plasma membrane-cytoskeleton interactions using optical tweezers and fluorescence imaging. J Biomech. 2007. 40(2):476-80.
  • Ermilov SA, Murdock DR, El-Daye D, Brownell WE, Anvari B. Effects of salicylate on plasma membrance mechanics. J Neurophysiol. 2005. 94:2105-10.
  • Liao Z, Popel AS, Brownell WE, Spector AA. Effect of voltage-dependent membrance properties on active force generation in cochlear outer hair cell. J Acoust Soci Am. 2005. 118:3737-46.
  • Liao Z, Popel AS, Brownell WE, Spector AA. High-frequency force generation in the constrained cochlear outer hair cell: a model study. J Assoc Res Otolaryngol. 2005. 6:378-89.
  • Liao Z, Popel AS, Brownell WE, Spector AA. Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment. J Acoust Soc Am. 2005. 117:2147-57.
  • Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B. Effects of chlorpromazine on mechanical properties of the outer hair cell plasma mambrane. Biophys J. 2005. 89:4090-5.
  • Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Ann Biomed Eng. 2005. 33:991-1002.

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