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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Arthur L. Beaudet, M.D.

Arthur L.Beaudet, M.D.

Professor and Chair
Department of Molecular and Human Genetics

Phone: 713-798-4795
Fax: 713-798-7773


  • M.D., Yale University School of Medicine
  • Residency, Pediatrics, John Hopkins Hospital
  • Postdoctoral, National Institutes of Health

Research Interests

  • Epigenetics
  • Autism
  • Microarrays
  • Halotype analysis
  • Prader-Willi syndrome

Clinical Focus

  • Genetic and epigenetic causes of autism
  • Prader-Willi and Angelman syndrome
  • Genetic diagnosis using array CGH
  • Gene therapy for cystic fibrosis
  • Crigler-Najjar
  • Hemophilia

Selected Publications

  • Brunetti-Pierri N, Ng T, Iannitti DA, Palmer DJ, Beaudet AL, Finegold MJ, Carey KD, Cioffi WG, Ng P. Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates. Hum Gene Ther. 2006. 17:391-404.
  • Van den Veyver IB, Beaudet AL. Comparative genomic hybridization and prenatal diagnosis. Curr Opin Obstet Gynecol. 2006. 18:185-91.
  • Wu MY, Chen KS, Bressler J, Hou A, Tsai TF, Beaudet AL. Mouse imprinting defect mutations that model Angelman syndrome. Genesis. 2006. 44:12-22.
  • Brunetti-Pierri N, Nichols TC, McCorquodale S, Merricks E, Palmer DJ, Beaudet AL, Ng P. Sustained phenotypic correction of canine hemophilia B after systemic administration of helper-dependent adenoviral vector. Hum Gene Ther. 2005. 16:811-20.
  • Cheung SW, Shaw CA, Yu W, Li J, Ou Z, Patel A, Yatsenko SA, Cooper ML, Furman P, Stankiewicz P, Lupski JR, Chinault AC, Beaudet AL. Development and validation of a CGH microarray for clinical cytogenetic diagnosis. Genet Med. 2005. 7:422-32. Erratum in: Genet Med 7:478.
  • Jiang YH, Bressler J, Beaudet AL. Epigenetics and Human Disease. Annu Rev Genomics Hum Genet. 2004. 5:479-510.
  • Jiang YH, Sahoo T, Michaelis RC, Bercovich D, Bressler J, Kashork CD, Liu Q, Shaffer LG, Schroer RJ, Stockton DW, Spielman RS, Stevenson RE, Beaudet AL. A Mixed Epigenetic/Genetic Model for Oligogenic Inheritance of Autism with a Limited Role for UBE3A. Am J Med Genet A. 2004. 131:1-10.

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