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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Marco Marcelli, M.D.

Marco Marcelli, M.D.Professor
Department of Medicine - Diabetes, Endocrinology, and Metabolism
Chief of Endocrinology, Michael E. DeBakey Veteran's Affairs Medical Center

Phone: 713-794-7945
Fax: 713-794-7714


  • M.D., University of Perugia Medical School (Italy)
  • Residency, Internal Medicine, University of Perugia Medical School
  • Fellowship, Molecular Endocrinology, The University of Texas Southwestern Medical Center,
    Dallas, TX
  • Clinical Fellowship, Endocrinology, The University of Texas Southwestern Medical Center,
    Dallas, TX

Research Interests

  • Androgen receptor biology, molecular biology
  • Imaging techniques of the androgen receptor
  • Disorders of male sexual differentiation
  • Outcome research in diabetes mellitus
  • Prostate cancer - mechanism of prostate cancer transition to androgen independence
  • General endocrinology
  • Diabetes mellitus

Selected Publications

  • Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes. 2009. 58(10):2292-302.
  • Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. PLoS One. 2009. 4(12):e8179.
  • Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH. Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation. Diabetes. 2008. 57(1):158-66.
  • Szafran AT, Szwarc M, Marcelli M, Mancini MA. Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One. 2008. 3(11):e3605.
  • Garcia JM, Iyer D, Poston WS, Marcelli M, Reeves R, Foreyt J, Balasubramanyam A. Rise of plasma ghrelin with weight loss is not sustained during weight maintenance. Obesity (Silver Spring). 2006. 14(10):1716-23.
  • Garcia JM, Li H, Mann D, Epner D, Hayes TH, Marcelli M, Cunningham GR. Hypogonadism in male patients with cancer. Cancer. 2006. 106:2583-91.
  • Marcelli M, Stenoien DL, Szafran AT, Simeoni S, Agoulnik IU, Weigel NL, Moran T, Mikic I, Price JH, Mancini MA. Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J Cell Biochem. 2006. 98(4):770-88.

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