Jeffrey L. Neul, M.D., Ph.D.
Department of Pediatrics - Neurology
- M.D., University of Chicago, Chicago IL
- Ph.D., Committee on Developmental Biology, University of Chicago, Chicago IL
- Residency, Child Neurology, Baylor College of Medicine, Houston TX
- Postdoctoral Fellowship, Huda Zoghbi Laboratory, Baylor College of Medicine, Houston TX
- Animal models of Rett syndrome
- Autonomic dysfunction in Rett syndrome
- Developing symptomatic and disease modifying therapies for Rett syndrome
- Rett syndrome
- Neurodevelopmental disorders
- Child neurology
- Samaco RC, Mandel-Brehm C, Chao HT, Ward CS, Fyffe-Maricich SL, Ren J, Hyland K, Thaller C, Maricich SM, Humphreys P, Greer JJ, Percy A, Glaze DG, Zoghbi HY, Neul JL. Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities. Proc Natl Acad Sci U S A. 2009. 106(51):21966-71.
- Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P, McGill BE, Goulding EH, Sullivan E, Tecott LH, Zoghbi HY. Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron. 2008. 59(6):947-58.
- Neul JL, Fang P, Barrish J, Lane J, Caeg EB, Smith EO, Zoghbi H, Percy A, Glaze DG. Specific mutations in methyl-CpG-binding protein 2 confer different severity in Rett syndrome. Neurology. 2008. 70(16):1313-21.
- Samaco RC, Fryer JD, Ren J, Fyffe S, Chao HT, Sun Y, Greer JJ, Zoghbi HY, Neul JL. A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome. Hum Mol Genet. 2008. 17(12):1718-27.
- Neul JL, Maricich SM, Islam M, Barrish J, Smith EO, Bottiglieri T, Hyland K, Humphreys P, Percy A, Glaze D. Spinal fluid 5-methyltetrahydrofolate levels are normal in Rett syndrome. Neurology. 2005. 64(12):2151-2.