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Translational Biology & Molecular Medicine

Houston, Texas

Benchtop, Research, Bedside and Application
Translational Biology & Molecular Medicine Graduate Program
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Jason T. Kimata, Ph.D.

Jason T. Kimata, Ph.D.Assistant Professor
Department of Molecular Virology and Microbiology

Phone: 713-798-4536
Fax: 713-798-4435


  • Ph.D., Washington University, St. Louis, MO
  • Postdoctoral Fellowship, University of Washington, Seattle, WA

Research Interests

  • Retroviral replication and pathogenesis
  • HIV-1 animal model development
  • Retrovirus induced cancers

Selected Publications

  • Biesinger T, Yu Kimata MT, Kimata JT. Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4+ T cells. Virology. 2008. 370(1):184-93.
  • Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M Jr, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, Hu SL, Coffin JM, Lifson JD, KewalRamani VN. Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy. J Virol. 2007. 81(22):12145-55.
  • Biggins JE, Biesinger T, Yu Kimata MT, Arora R, Kimata JT. ICAM-3 influences human immunodeficiency virus type 1 replication in CD4(+) T cells independent of DC-SIGN-mediated transmission. Virology. 2007. 364(2):383-94.
  • Kimata JT. HIV-1 fitness and disease progression: insights from the SIV-macaque model. Curr HIV Res. 2006. 4(1):65-77.
  • Lee SJ, Arora R, Bull LM, Arduino RC, Garza L, Allan J, Kimata JT, Zhou P. A nonneutralizing anti-HIV Type 1 antibody turns into a broad neutralizing antibody when expressed on the surface of HIV type 1-susceptible cells. II. Inhibition of HIV type 1 captured and transferred by DC-SIGN. AIDS Res Hum Retroviruses. 2006. 22(9):874-83.
  • Kimata JT, Kuller L, Anderson DB, Dailey P, Overbaugh J. Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression. Nat Med. 1999. 5(5):535-41.

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