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Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
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Andreas Tolias, Ph.D.

Assistant Professor, NeuroscienceAndreas Tolias, Ph.D.

SCBMB Executive Committee Member

Baylor College of Medicine


Ph.D., Massachusetts Institute of Technology, 1999

Research Interest:

The goal of Dr. Tolias' research is to understand how visual information is perceived, learned and used to guide behavior. These visually-based processes rely on activation patterns in neural circuits distributed across more than 20 distinct regions of the primate brain. Therefore to fully understand the neural mechanisms of vision, it is essential to study networks of neurons. Although these issues have long been appreciated as fundamental, research examining the properties of networks of neurons in primates has only recently become possible with the advent of techniques like chronic multi-electrode recordings.

For his lab's studies, they use chronic multi-tetrode recordings which enable us to record simultaneously from many neurons across multiple brain areas in awake, behaving primates. Chronic tetrode recordings provide us with a unique opportunity to study learning since we can record from the same neurons across multiple days. These experiments are done in combination with behavioral, fMRI and computational approaches. Improved understanding of how visual perception and learning are accomplished through computations distributed across neuronal populations will help us understand the principles of neural coding. It is also likely to have important implications for the theory of artificial intelligence and robotics and, eventually, for the successful development of brain-machine interface systems including visual prostheses.

Selected Publications:

  • Subramaniyan M, Ecker AS, Berens P and Tolias AS. Macaque monkeys perceive the flash lag illusion. PLoS One, 8(3):e58788 (2013). PubMed
  • Beauchamp MS, Sun P, Baum SH. Tolias AS and Yoshor D. Electrocorticography links human temporoparietal junction to visual perception. Nat Neurosci, 15(7):957-959 (2012). PubMed
  • Ecker AS, Berens P, Tolias AS and Bethge M. The effect of noise correlations in populations of diversely tuned neurons. J Neurosci, 31(40):14272-83 (2011). PubMed
  • Sultan F, Augath M, Murayama Y, Tolias A.S. and Logothetis, N. esfMRI of the upper STS: further evidence for the lack of electrically induced polysynaptic propagation of activity in the neocortex. Magn Reson Imaging, 29(10):1374-81 (2011). PubMed
  • Ku SP, Tolias AS, Logothetis NK and Goense J. fMRI of the face-processing network in the ventral temporal lobe of awake and anesthetized macaques. Neuron, 70(2):352-62 (2011). PubMed
  • Berens P, Ecker AS, Gerwinn S, Tolias AS and Bethge M. Reassessing optimal neural population codes with neurometric functions. Proc Natl Acad Sci USA, 108(11):4423-8 (2011). PubMed
  • Keliris GA, Logothetis NK and Tolias AS. The role of the primary visual cortex in perceptual suppression of salient visual stimuli. J Neurosci, 30(37):12353-65 (2010). PubMed

For more publications, see listing on PubMed.

Contact Information:

Department: Neuroscience
Address: Baylor College of Medicine
One Baylor Plaza
ouston, Texas 77030
Phone: 713-798-4071
Fax: 713-798-2874

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