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Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
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Structural Biology

Patrick Barth, Ph.D. Baylor College of Medicine. Signaling mechanisms across biological membranes by computational modeling, design and experimental biophysics.

James Briggs, Ph.D. University of Houston. Computer-aided drug design; Molecular modeling; Computational biophysics.

William Brinkley, Ph.D.Baylor College of Medicine. Structure and assembly of the mitotic apparatus; molecular mechanisms for aneuploidy and genomic instability in tumor cells.

William Brownell, Ph.D. Baylor College of Medicine. Cochlear biophysics and the mechanism of outer hair cell electromotility.

Wah Chiu, Ph.D. Baylor College of Medicine. Structural and Computational Biology of Biological Machines.

Cecilia Clementi, Ph.D. Rice University. Theory of Protein Folding; Protein Modeling and Simulations; Folding/Function relationship.

Mary Estes, Ph.D. Baylor College of Medicine. Molecular biology and structure of virus assembly.

George E. Fox, Ph.D. University of Houston. RNA structure, function & evolution; bioinformatics.

H.F. Gilbert, Ph.D. Baylor College of Medicine. Protein folding and catalysis of disulfide formation during protein secretion in yeast.

David Gorenstein, Ph.D. University of Texas Health Science Center. Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer.

Susan Hamilton, Ph.D. Baylor College of Medicine. Calcium Release Channel Structure and Function.

Lydia Kavraki, Ph.D. Rice University. Computation of Shape and Motion in Biology, Computer-Assisted Drug Design.

Choel Kim, Ph.D. Baylor College of Medicine. Signaling Mechanisms of NO/cGMP (Viagra) Pathway. Developing Novel Thera peutics for Hypertensive Diseases. Structure-Guided Rational Drug Design.

Suzanne Leal, Ph.D. Baylor College of Medicine. Statistical Genetics and Genetic Epidemiology.

Olivier Lichtarge, M.D., Ph.D. Baylor College of Medicine. Annotation and Designed Perturbation of Protein Function and Pathways.

Jun Liu, Ph.D. University of Texas Health Science Center. 3-D structure/function of macromolecular assemblies, bacteria and enveloped viruses; AIDS virus; viral entry and antibody neutralization.

Steve Ludtke, Ph.D. Baylor College of Medicine. Cryo-electron microscopy and single particle reconstruction.

Jianpeng Ma, Ph.D. Baylor College of Medicine. Computational Molecular Biophysics and Structural Biology.

Pawel Penczek, Ph.D. University of Texas. Structural Determinatin of Proteins and Molecular Assemblies.

B. Montgomery Pettitt, Ph.D. University of Texas Medical Branch, Galveston. Theoretical and computational biology and biochemistry.

Henry J. Pownall, Ph.D. The Methodist Hospital Research Institute. Structures of Native and Model Plasma Lipoproteins.

B.V.V. Prasad, Ph.D. Baylor College of Medicine. Structural biology of replication mechanisms in pathogens such as rotavirus, norovirus, and influenza virus.

Florante Quiocho, Ph.D. Baylor College of Medicine. Protein Atomic Structure, Molecular Recognition and Function.

Michael F. Schmid, Ph.D. Baylor College of Medicine. Image Processing and Electron Crystallography of Macromolecular Machines.

Richard Sifers, Ph.D. Baylor College of Medicine. Glycobiology; regulation of endoplasmic reticulum degradation; conformational disease; alpha1-antitrypsin deficiency.

Yongcheng Song, Ph.D. Baylor College of Medicine. Rational design and synthesis of novel inhibitors for drug discovery and chemical biology.

John L. Spudich, Ph.D. Unversity of Texas Houston Medical School. Photosensory Receptors & Signal Transduction / Microbial Rhodopsins.

Francis Tsai, D. Phil. Baylor College of Medicine. Structure and Function of Macromolecular Complexes and Supramolecular Assemblies.

Salih J. Wakil, Ph.D.** Baylor College of Medicine. Structure, Function, and Regulation of the Multifunctional Enzymes, Acetyl-CoA Carboxylase and Fatty Acid Synthase.

Ted Wensel, Ph.D. Baylor College of Medicine. Structure and Dynamics of Signal Transducing Membranes.

Lynn Zechiedrich, Ph.D. Baylor College of Medicine. DNA topoisomererases and antimicrobial resistance.

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