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Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
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Samuel M. Wu, Ph.D.

Samuel M. Wu, Ph.D.The Camille and Raymond Hankamer Chair in Ophthalmology

Professor, Ophthalmology, Molecular Physiology and Biophysics, and Neuroscience

Baylor College of Medicine

Education:

Ph.D. Biophysics, Harvard University

Research Interests:

Electrophysiology of the vertebrate retina; membrane biophysics; electrical and pharmacological properties of retinal synapses; retinal circuitry and visual perception.

Selected Publications:

  • Frankfort BJ, Khan AK, Tse DY, Chung I, Pang JJ, Yang Z, Gross RL and Wu SM. Elevated intraocular pressure causes inner retinal dysfunction before cell loss in a mouse model of experimental glaucoma. Invest Ophthalmol Vis Sci, 54(1):762-70 (2013). PubMed
  • Pang JJ, Gao F and Wu SM. Ionotropic glutamate receptors mediate OFF responses in light-adapted ON bipolar cells. Vision Res, 68:48-58 (2012). PubMed
  • Pang JJ, Gao F, Paul DL and Wu SM. Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina. J Physiol, 590(Pt4):845-54 (2012). PubMed
  • Pang JJ, Gao F and Wu SM. Physiological characterization and functional heterogeneity of narrow-field mammalian amacrine cells. J Physiol, 590(Pt 1):223-34 (2012). PubMed
  • Price BA, Sandoval IM, Chan F, Simons DL, Wu SM, Wensel TG and Wilson JH. Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa. Invest Ophthalmol Vis Sci, 52(13):9728-36 (2011). PubMed
  • Pang JJ and Wu SM. Morphology and immunoreactivity of retrogradely double-labeled ganglion cells in the mouse retina. Invest Ophthamol Vis Sci, 52(7):4886-96 (2011). PubMed
  • Zhang AJ, Jacoby R and Wu SM. Light- and dopamine-regulated receptive field plasticity in primate horizontal cells. J Comp Neurol, 519(11):2125-34 (2011). PubMed

For more publications, see listing on PubMed.

Contact Information:

Department: Ophthalmology
Address: Baylor College of Medicine
One Baylor Plaza
NEUR-C416
NC205
Houston, TX 77030
Phone: 713-798-5966
Fax: 713-798-6457
E-mail: swu@bcm.edu
Additional Links: Ophthalmology

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