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Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
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Samuel M. Wu, Ph.D.

Samuel M. Wu, Ph.D.The Camille and Raymond Hankamer Chair in Ophthalmology

Professor, Ophthalmology, Molecular Physiology and Biophysics, and Neuroscience

Baylor College of Medicine


Ph.D. Biophysics, Harvard University

Research Interests:

Electrophysiology of the vertebrate retina; membrane biophysics; electrical and pharmacological properties of retinal synapses; retinal circuitry and visual perception.

Selected Publications:

  • Frankfort BJ, Khan AK, Tse DY, Chung I, Pang JJ, Yang Z, Gross RL and Wu SM. Elevated intraocular pressure causes inner retinal dysfunction before cell loss in a mouse model of experimental glaucoma. Invest Ophthalmol Vis Sci, 54(1):762-70 (2013). PubMed
  • Pang JJ, Gao F and Wu SM. Ionotropic glutamate receptors mediate OFF responses in light-adapted ON bipolar cells. Vision Res, 68:48-58 (2012). PubMed
  • Pang JJ, Gao F, Paul DL and Wu SM. Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina. J Physiol, 590(Pt4):845-54 (2012). PubMed
  • Pang JJ, Gao F and Wu SM. Physiological characterization and functional heterogeneity of narrow-field mammalian amacrine cells. J Physiol, 590(Pt 1):223-34 (2012). PubMed
  • Price BA, Sandoval IM, Chan F, Simons DL, Wu SM, Wensel TG and Wilson JH. Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa. Invest Ophthalmol Vis Sci, 52(13):9728-36 (2011). PubMed
  • Pang JJ and Wu SM. Morphology and immunoreactivity of retrogradely double-labeled ganglion cells in the mouse retina. Invest Ophthamol Vis Sci, 52(7):4886-96 (2011). PubMed
  • Zhang AJ, Jacoby R and Wu SM. Light- and dopamine-regulated receptive field plasticity in primate horizontal cells. J Comp Neurol, 519(11):2125-34 (2011). PubMed

For more publications, see listing on PubMed.

Contact Information:

Department: Ophthalmology
Address: Baylor College of Medicine
One Baylor Plaza
Houston, TX 77030
Phone: 713-798-5966
Fax: 713-798-6457
Additional Links: Ophthalmology

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