skip to content »

Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
not shown on screen

William Brinkley, Ph.D.

William Brinkley, Ph.D.Distinguished Service Professor, Molecular and Cellular Biology

Baylor College of Medicine

Education:

Ph.D., Iowa State University
Postdoc, The University of Texas MD Anderson Cancer Center

Research Interests:

Structure and assembly of the mitotic apparatus; molecular mechanisms for aneuploidy and genomic instability in tumor cells.

Selected Publications:

  • Brinkley BR. Mitotic checkpoints, MUGs and kinetochores. Cell Cycle, 12(12) (2013). PubMed
  • Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR and Mancini MA. A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Techol., 10(2):161-78 (2012). PubMed
  • Slattery SD, Mancini MA, Brinkley BR and Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle, 8(18):2984-94 (2009). PubMed
  • Slattery SD, Moore RV, Brinkley BR and Hall RM. Aurora-C and Aurora-B share phophorylation and regulation of CENP-A and Borealin during mitosis. Cell Cycle, 7(6):787-95 (2008). PubMed
  • Caulin C, Ngyuen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G and Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J. Clin. Invest, 117(7):1893-901 (2007). PubMed
  • MacCorkle RA, Slattery SD, Nash DR and Brinkley BR. Intracellular protein binding to asbestos induces aneuploidy in human lung fibroblasts. Cell Motil Cytoskeleton, 63(10):646-57 (2006). PubMed
  • Nishino M, Kurasawa Y, Evans R, Lin SH, Brinkley BR and Yu-Lee LY. NudC is required for Plk1 targeting to the kinetochore and chromosome congression. Curr Biol., 16(14):1414-21 (2006). PubMed

For more publications, see listing on PubMed.

Contact Information:

Department: Molecular & Cellular Biology
Address: Room N204
Baylor College of Medicine
One Baylor Plaza
Houston, Texas 77030
Phone: 713-798-5263
Fax: 713-798-6325
E-mail: brinkley@bcm.edu

E-mail this page to a friend