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Structural and Computational Biology and Molecular Biophysics

Houston, Texas

A BCM research lab.
Structural and Computational Biology & Molecular Biophysics
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Faculty M-Z

Jianpeng Ma, Ph.D. Baylor College of Medicine. Computational molecular biophysics and structural biology.

Mirjana Maletic-Savatic, M.D., Ph.D. Baylor College of Medicine. Imaging metabolomics and neurogenesis.

Chris Tsz-Kwong Man, Ph.D. Baylor College of Medicine. Identification of biomarkers and therapeutic targets, understanding the mechanism of chemoresistanc and metastasis in pediatric cancer at a systems level.

Michael Mancini, Ph.D. Baylor College of Medicine. Transcriptional analyses at the single cell level.

Aleksandar Milosavljevic, Ph.D.** Baylor College of Medicine. Bioinformatics, genomics, epigenomics, and cancer.

Luay Nakhleh, Ph.D. Rice University. Computational biology and bioinformatics.

Jose Onuchic, Ph.D. ** Rice University. Protein folding and function, electron transfer in proteins, and stochasticity and noise in gene networks.

Timothy Palzkill, Ph.D. Baylor College of Medicine. Molecular basis of antibiotic resistance, functional genomics of bacterial pathogens.

Steen E. Pedersen, Ph.D. Baylor College of Medicine. Allosteric mechanisms of ion channel function.

Pawel Penczek, Ph.D. University of Texas Health Science Center. Structural determination of proteins and molecular assemblies.

B. Montgomery Pettitt, Ph.D.**University of Texas Medical Branch at Galveston. Theoretical and computational biophysics and biochemistry, protein design, drug screening and design.

Paul J. Pfaffinger, Ph.D. Baylor College of Medicine. Molecular biology and biophysics of potassium ion channels.

Henry J. Pownall, Ph.D. The Methodist Hospital Research Institute. Structures of-function relationships for lipoprotein therapeutics.

B.V.V. Prasad, Ph.D. Baylor College of Medicine. Structural biology of replication mechanisms in pathogens such as rotavirus, norovirus, and influenza virus.

Jun Qin, Ph.D. Baylor College of Medicine. Network analysis proteomics; the human DNA damage signaling network.

Florante Quiocho, Ph.D. Baylor College of Medicine. Protein atomic structure, molecular recognition, and function.

Arvind Rao, Ph.D. The University of Texas M.D. Anderson Cancer Center. Image analysis, machine learning,a nd combining imaging with genomics data across biological scale.

Robert Raphael, Ph.D. Rice University. Cell membrane mechanics, thermodynamics and biophysics.

Peter Saggau, Ph.D. Baylor College of Medicine. Mechanisms and modulation of synaptic transmission; single neuron computation; advanced optical imaging techiniques in neuroscience.

Michael F. Schmid, Ph.D. Baylor College of Medicine. Image processing and electron cryo-tomography of macromolecular assemblies, including cellular motors and virus encapsidation machines.

Gad Shaulsky, Ph.D. Baylor College of Medicine. Functional genomics and new data mining tools; The evolution of social behavior and allorecognition in Dictyostelium.

Chad Shaw, Ph.D. Baylor College of Medicine. Allorecognition, evolution of sociality and functional genomics in Dictyostelium.

Joshua M. Shulman, M.D., Ph.D. Baylor College of Medicine. Human Genetics and Drosophilia Genetics.

Richard Sifers, Ph.D. Baylor College of Medicine. Glycobiology; regulation of endoplasmic reticulum degradation; conformational disease; alpha1-antitrypsin deficiency.

Stelios Manolis Smirnakis, M.D., Ph.D. Baylor College of Medicine. In vivo functional magnetic resonance imaging, electrophysiology, and two-photon techniques in the study of cortical network function in health and disease.

Jack W. Smith M.D., Ph.D.** University of Texas Health Science Center. Decision-support systems and intelligent-tutoring.

Yongcheng Song, Ph.D. Baylor College of Medicine. Rational design and synthesis of novel inhibitors for drug discovery and chemical biology.

John L. Spudich, Ph.D. Unversity of Texas Health Science Center. Photosensory receptors and signal transduction / microbial rhodopsins.

Andreas Tolias, Ph.D. ** Baylor College of Medicine. Electrophysiological, computational and functional imaging approaches to processing of visual information in the cerebral cortex of alert behaving primates.

Francis Tsai, D. Phil. Baylor College of Medicine. Structure and function of macromolecular complexes and supramolecular assemblies.

David Tweardy, M.D. Baylor College of Medicine. Structure-based drug design to target inflammatory and oncogenic signaling pathways.

Salih J. Wakil, Ph.D. Baylor College of Medicine. Structure, function, and regulation of the multifunctional enzymes, acetyl-CoA carboxylase and fatty acid synthase.

Ted Wensel, Ph.D.** Baylor College of Medicine. Structure and dynamics of signal transducing membranes.

Richard Willson, Ph.D. University of Houston. Chemical and biomolecular engineering, biology, and biochemistry.

John Wilson, Ph.D. Baylor College of Medicine. Instability of trinucleotide repeats in human disease; gene therapy for diseases of the eye.

Peter Wolynes, Ph.D. Rice University. Theoretical and computational studies in structural and cellular biology.

Steve Wong, Ph.D. The Methodist Hospital Research Institute. Chemical and systems biology in drug discovery and repositioning.

Samuel M. Wu, Ph.D. Baylor College of Medicine. Synaptic biophysics of retinal neurons and eye diseases.



Whitney Yin, M.D. Ph.D. University of Texas Medical Branch. Mitochondrial DNA replication and damage repair.

Lynn Zechiedrich, Ph.D.** Baylor College of Medicine. DNA topoisomererases and antimicrobial resistance.

**Denotes Executive Committee Member

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