Research Trials

Division

Description

Funding Source(s)

PI

Abdominal Transplant

A randomized, double-blind, placebo-controlled, dose-ranging, multicenter study to assess the efficacy and safety of Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the treatment of overt hepatic encephalopathy (OHE)

Bausch Health Americas

Dr. Prasun Jalal

Abdominal Transplant

Efficacy and safety of ALXN1840 administered for 48 weeks versus standard of care in patients with Wilson Disease

Alexion/ Wilson Therapeutics

Dr. Norman Sussman

Abdominal Transplant

AURORA: A phase 3 study to evaluate the efficacy and safety of Cenicriviroc for the treatment of liver fibrosis in adult subjects with nonalcoholic steatohepatitis

Allergan/ Tobira Therapeutics

Dr. Norman Sussman

Cardiothoracic Surgery

Post-approval study of the Relay® thoracic stent-graft with plus delivery system in patients with thoracic aortic aneurysms and penetrating ulcers

Bolton Medical

Dr. Joseph Coselli

Cardiothoracic Surgery

Trifecta GT post market clinical follow-up

St. Jude Medical/ Abbot

Dr. Joseph Coselli

Cardiothoracic Surgery

Medtronic Evolut transcatheter aortic valve replacement in low risk patients

Medtronic

Dr. Joseph Coselli

Cardiothoracic Surgery

Evaluation of the Valiant Mona LSA thoracic stent graft system in descending thoracic aortic aneurysms and chronic dissections

Medtronic

Dr. Joseph Coselli

Cardiothoracic Surgery

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation (APOLLO)

Medtronic

Dr. Joseph Coselli

Cardiothoracic Surgery

Evaluation of the Thoraflex™ Hybrid Device for use in the repair or replacement of the ascending aorta, aortic arch and descending aorta in an open surgical procedure

Terumo Cardiovascular Systems

Dr. Joseph Coselli

Cardiothoracic Surgery

Evaluation of the Gore® ascending stent graft in the treatment of DeBakey type I/II aortic dissection

W.L. Gore & Associates

Dr. Joseph Coselli

Cardiothoracic Surgery

CytoSorb® Reduction of FREee Hemoglobin/Acute Kidney Injury (AKI) During Cardiac Surgery (REFRESH II Trial)

Cytosorbents

Dr. Scott LeMaire

Cardiothoracic Surgery

ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Aortic and Mitral Bioprostheses (Models 11000A and 11000M) With a New Tissue Treatment Platform (COMMENCE)

Edwards Lifesciences

Dr. Todd Rosengart

Cardiothoracic Surgery

Evaluating the benefit of concurrent tricuspid valve repair during mitral surgery

NHLBI/ Edwards Lifesciences

Dr. Todd Rosengart

Cardiothoracic Surgery

Multi-center experience with the rapid deployment Edwards Intuity valve system for aortic valve replacement (TRANSFORM)

Edwards Lifesciences

Dr. Todd Rosengart

Cardiothoracic Transplant & Circulatory Support

Trial to evaluate the safety and effectiveness of the portable Organ Care System (OCS™) Lung System for recruiting, preserving and assessing non-ideal donor lungs for transplantation (EXPAND II)

Transmedics

Dr. Gabriel Loor

Cardiothoracic Transplant & Circulatory Support

Syncardia 50cc temporary total artificial heart as a bridge to transplant

SynCardia Systems/NHLBI

Dr. Kenneth Liao

General Surgery

The prospective diagnosis of depression in surgical patients

Department of Defense

Dr. David S. Lee

General Surgery

Prospective comparative effectiveness trial for malignant bowel obstruction

National Cancer Institute

Dr. Eric  Silberfein

General Surgery

ConMed HelixAR™ ElectroSurgical generator with argon beam coagulation Technology (CHEST)

ConMed HelixAR

Dr. Stacey Carter

General Thoracic Surgery

Phase II study of MEDI4736 or MEDI4736 + tremelimumab in surgically resectable malignant pleural mesothelioma

Astrazeneca Healthcare Foundation

Dr. Bryan Burt

General Thoracic Surgery

Study of cytoreductive surgery and hyperthermic intraoperative chemotherapy with Pemetrexed and Cisplatin for malignant pleural mesotheliomas

Baylor College of Medicine

Dr. Bryan Burt

Pediatric Surgery

Timing of inguinal hernia repair in premature infants: a randomized trial

Vanderbilt University

Dr. Monica Esperanza Lopez

Vascular Surgery

An international, multicenter, randomized, double-blind, placebo-controlled phase 3 trial investigating the efficacy and safety of Rivaroxaban to reduce the risk of major thrombotic vascular events in patients with symptomatic peripheral artery disease undergoing lower extremity revascularization procedures (VOYAGER)

Bayer

Dr. Joseph Mills

Vascular Surgery

Temsirolimus adventitial delivery to improve angiographic outcomes below the knee (TANGO)

Mercator MedSystems

Dr. Miguel Montero

Vascular Surgery

Shockwave medical peripheral lithoplasty system study for PAD (Disrupt PAD III)

Shockwave

Dr. Miguel Montero

Vascular Surgery

Avex footbeat--micro-mobile foot compression device for reducing lower extremity edema in patients with diabetes: a proof of concept study

Avex Footbeat

Dr. Bijan Najafi

Vascular Surgery

Managing chemotherapy induced neuropathy in cancer patients using exergaming

National Cancer Institute

Dr. Bijan Najafi

Vascular Surgery

STTR phase I: smart residential carpet for promoting aging in place

Philips Medical Systems/ Volcano Corporation

Dr. Bijan Najafi

Vascular Surgery

Comparative effectiveness of two acellular matrices  products (Dermacell v. Integra) for management of  deep diabetic foot ulcers - a randomized clinical  trial

National Institutes of Health

Dr. Bijan Najafi

Vascular Surgery

Novel offloading for diabetic foot ulcers with pulseflow df®: a prospective study

National Institutes of Health

Dr. Bijan Najafi

Vascular Surgery

Electrical stimulation as an adjunctive therapy to accelerate wound healing in people with diabetic foot ulcers - a randomized controlled trial

Avazzia

Dr. Bijan Najafi

Vascular Surgery

Evaluation of oxygen delivery with transcu O2 to study success rate of surgically closed  wounds - a randomized controlled trial

Conatus Pharmaceuticals

Dr. Bijan Najafi

Vascular Surgery

Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes (STANCE)

Columbia University

Dr. Tony Lu