Our mission is to conduct impactful research in surgical disease to improve treatment and quality of life for affected patients, and to train future leaders in academic surgery and the next generation of academic surgical investigators. We are dedicated to creating an environment where surgical investigators discover new knowledge, develop innovations, and translate research advances into improvements in patient care. We accomplish these goals through several departmental programs:

The Office of Surgical Research team, led by Dr. Barbara W. Trautner, is composed of nearly 50 professionals, including grants managers, clinical research coordinators, database managers, biostatisticians, medical illustrators, and a medical editor and writer, who provide easily accessible, centralized expertise in clinical research.

Resident research training fellowships are the cornerstone experience for our general surgery residents in the Research Track. This track provides four of our eight categorical residents with a two-year mentored research experience in basic science, clinical research, heath services research, or bioengineering and biodesign. We also have an NIH-funded T32 training program in cardiovascular surgery research. Learn about research opportunities for residents in our General Surgery Residency and T32 Program.

Surrounding these core programs are a matrix of faculty seed grants, Office of Surgical Research-sponsored weekly symposia and grant review sessions, a research curriculum for residents, and the INSTINCT℠ surgical innovation program led by Dr. Stuart Corr, all designed to foster and support the research mission. A growing number of campus-wide databases enable clinical research evaluating patient care throughout our program.

credit: Scott Holmes
Cancer Research

The Department of Surgery’s world-class scientists are revolutionizing prevention, detection and treatment for several cancers. Key areas of research focus are: genetics and genomics, translational technology, immunotherapy and vaccines, microbiology, and clinical trials, with an emphasis on thoracic, endocrine, and gastrointestinal cancers.

credit: Circulation Research
Cardiovascular Research

The Michael E. DeBakey Department of Surgery is a world leader in cardiac and vascular innovation. Together with our partner, the Texas Heart Institute, the department's cardiovascular research program is at the forefront of developing translational and clinical therapies for cardiovascular disease.

credit: Scott Holmes
Surgical Outcomes, Health Services, and Quality and Safety Research

Faculty in the Michael E. DeBakey Department of Surgery play a key role in wide variety of quality improvement initiatives and surgical outcomes studies in the United States and across the globe. Our investigators’ research projects are funded by grants from the NIH, VA Office of Research & Development, the Cancer Prevention & Research Institute of Texas, foundations and industry.

credit: Scott Holmes
Transplantation Research

Since the 1960s, when Dr. Michael E. DeBakey obtained the first federal grant to develop an artificial heart, Baylor College of Medicine has remained an international leader in the quest to discover new treatments for advanced diseases of the heart and lung. Today, innovation remains the hallmark of our research programs in solid organ transplantation, mechanical assist devices, organ preservation, surgical procedures, immunosuppressive medications and transplant outcomes.