The Aortic Disease Research Laboratory, led by Ying H. Shen, M.D., Ph.D., associate professor of surgery, won the Cardiac Surgery Biology Club Cup Competition for their presentation “Primum non nocere: Are we causing aortic catastrophes by prescribing antibiotics?” which Scott A. LeMaire, M.D., professor and vice chair for research in the Department of Surgery, delivered at the American Association for Thoracic Surgery (AATS) 98th Annual Meeting, held in San Diego, Calif., April 28 to May 1, 2018.

The Aortic Disease Research Laboratory maintains one of the world’s most extensive and well-cataloged aortic tissue banks. This core resource facilitates investigations into the causes and progression of aortic disease pursued by Baylor College of Medicine researchers, as well as researchers from other academic institutions.

The lab's main focus is aortic aneurysms and dissections, life-threatening diseases caused by progressive degeneration of the aortic wall. We have several ongoing projects investigating the mechanisms of aortic destruction, repair, and remodeling. The ultimate goal of our research is to develop pharmacological treatments to prevent progressive aortic degeneration, maladaptive remodeling, and disease progression.