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Department of Physical Medicine & Rehabilitation

Houston, Texas

A physician explains an X-ray image.
Department of Physical Medicine and Rehabilitation
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Rabih O. Darouiche, M.D.

Photo Rabih O. Darouiche, M.D.Professor

Medical School: American University of Beirut, Lebanon, 1984
Internship: Baylor College of Medicine, Houston, Texas
Residency: Baylor College of Medicine, Houston, Texas
Fellowship: Infectious Diseases, Baylor College of Medicine, Houston, Texas

Board Certification: American Board of Internal Medicine, American Board of Infectious Disease, American Board of Spinal Cord Injury Medicine

Sub-Specialty: Spinal Cord Injury
Clinical Interests: Infections in patients with spinal cord injury; medical device-related infections
Research Interest: Prostheses-related infections; infections in patients with spinal cord injury

Significant Professional Activities:
  • Houston Intellectual Property Law Association
    • 2004 HIPLA Inventor of the Year Award
  • Society for Healthcare Epidemiology of America
    • Investigator Award
  • Clinical Infectious Diseases
    • Member, Review Panel
  • Antimicrobial Agents and Chemotherapy
    • Member, Review Panel
  • Annals of Internal Medicine
    • Member, Review Panel
  • Archives of Internal Medicine
    • Member, Review Panel
  • Wayne State University, Infectious Disease Consultant Exchange
    • Medical Consultant
  • Pfizer U.S. Pharmaceuticals
    • Member, Advisory Panel
  • Society for Healthcare Epidemiology of America
    • Member, Annual Meeting Planning Committee
  • Multidisciplinary Alliance Against Device-Related Infections (MADRI)
    • Founder
  • American Paraplegia Society
    • Member, Board of Directors
    • Member, Research Committee
  • Combined Annual Meeting of the Center for Prostheses Infection and Multidisciplinary Alliance Against Device-Related Infections
    • Program Director
  • American College of Physicians
    • Fellow
Selected Publications:

Cook G, Costerton JW, Darouiche RO. Direct confocal microscopy studies of the bacterial colonization in vitro of a silver-coated heart valve sewing cuff. International Journal Antimicrob Agents13:169-173, 2000.

Hull RA, Rudy DC, Donovan WH, Svanborg C, Steward C, Wieser IE, Darouiche RO. Urinary tract infection prophylaxis using Escherichia coli 83972 in spinal cord injured patients. Journal of Urology 163: 872-877, 2002.

Darouiche RO. Infection-resistant alloplasts. Journal Endourology 14:33-37, 2000.

Darouiche RO, Hull RA. Bacterial interference for prevention of urinary tract infection: an overview. Journal Spinal Cord Medicine 23:136-141, 2000.

Cole AM, Darouiche RO, Lagarda D, Connell N, Diamond G. Characterization of a fish antimicrobial peptide: Gene expression, subcellular localization and spectrum of activity. Antimicrobial Agents Chemotherapy 44:2039-2045, 2000.

Darouiche RO, Donovan WH, Del Terzo M, Thornby JI, Rudy DC, Hull RA. Pilot trial of bacterial interference for preventing urinary tract infection. Urology, 58:339-344, 2001.

Trautner BW, Darouiche RO. Tuberculous pericarditis: optimal diagnosis and management. Clin Infect Dis, 33:954-961, 2001.

Darouiche RO. Device-associated infections: a macroproblem that starts with microadherence. Clin Infect Dis, 33:1567-1572, 2001.

Raad II, Hanna HA, Darouiche RO. Diagnosis of catheter-related bloodstream infections: is it necessary to culture the subcutaneous catheter segment? Eur J Clin Microbiol Infect Dis, 20:566-568, 2001.

Kojic EM, Darouiche RO, Clarridge J, Hamill FJ. Bilateral psoas abscess due to Neisseria elongata spp. nitroducens in a patient with immune reconstitution syndrome. Infect Dis Clin Pract, 10:399-402, 2001.

Trautner BW, Darouiche RO, Hull RA, Hull S, Thornby J. Biofilm of Escherichia coli 83972 on urinary catheters inhibits catheter colonization by Enterococcus faecalis. J Urol, 167:375-379, 2002.

Darouiche RO, Fowler VG, Adal K, et al. Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin. Antimicrob Agents Chemother, 46:543-545, 2002.

Darouiche RO, Mansouri MD, Raad II. Efficacy of antimicrobial-impregnated silicone sections from penile implants in preventing device colonization in an animal model. Urology, 59:303-307, 2002.

Darouiche RO, Mansouri MD, Meade R. In-vitro and in-vivo activity of antimicrobial-coated prosthetic heart valve sewing cuffs. J Heart Valve Dis, 11:99-104, 2002.

Darouiche RO, Meade R, Mansouri MD, Netscher DT. In vivo efficacy of antimicrobial-impregnated saline-filled silicone implants. Plastic Reconstr Surg, 109:1352-1357, 2002.

Trautner BW, Clarridge J, Darouiche RO. Skin disinfection kits containing chlorhexidine gluconate or tinture of iodine are associated with low rates of blood culture contamination. Infect Contr Hosp Epidemiology, 23:397-401, 2002.

Musher D, Goldsmith E, Dunbar S, Tilney G, Darouiche R, Qinghua Y, Lopez JA, Dong J. Association of hypercoagulable states and increased platelet adhesion and aggregation with bacterial colonization of intravenous catheters. J Infect Dis, 186:769-773, 2002.

Hull RA, Donovan WH, del Terzo M, Stewart C, Rogers M, Darouiche RO. Role of type 1 fimbria- and P fimbria-specific adherence in colonization of the neurogenic human bladder by Escherichia coli. Infect Immun, 70:6481-6484, 2002.

Lewis RE, Kontoyiannis DP, Darouiche RO, Raad II, Prince RA. Antifungal activity of amphotericin B, fluconazole, and voriconazole in an in vitro model of Candida catheter-related bloodstream infection. Antimicrob Agents Chemother, 46:3499-3505, 2002.

Trautner BW, Darouiche RO. Prevention of urinary tract infection in patients with spinal cord injury. J Spinal Cord Med, 25:277-283, 2002.

Darouiche RO, Netscher DT, Meade R, Mansouri MD. Activity of antimicrobial-impregnated silicone tissue expanders. Ann Plastic Surg, 49:567-71, 2002.

Zambramski JM, Whiting D, Darouiche RO, et al. Efficacy of antimicrobial-impregnated external ventricular drain catheters: a prospective, randomized, controlled trial. J Neurosurg, 98:725-30, 2003.

Trautner BW, Hull RA, Darouiche RO. Escherichia coli 83972 inhibits catheter adherence by a broad spectrum of uropathogens. Urology, 61:1059-62, 2003.

Darouiche RO. Antimicrobial approaches for preventing infections associated with surgical implants. Clin Infect Dis, 36:1284-9, 2003.

Darouiche RO. Nosocomial bloodstream infections and second generation vascular catheters. In: Wenzel RP (Ed.) Prevention and Control of Nosocomial Infections (4th edition). Baltimore, Lippincott Williams & Wilkins, 2003.

Darouiche RO, Mansouri MD. Dalbavancin vs. Vancomycin for prevention of staphylococcus aureus colonization of devices in an animal model. Proceedings of the 41st Annual Meeting of The Infectious Disease Society of America, 2003. Abstract #174.

Darouiche R, Mansouri D, Raad I. In-vivo analysis of the impact of antimicrobial-impregnated catheters on antimicrobial resistance. Proceedings of the 41st Annual Meeting of the Infectious Disease Society of America, (San Diego, California), 2003. Abstract #556.

Chatzinikolaou I, Hanna H, Darouiche R, et al. The value of quantitative blood cultures collected through central venous catheters in establishing the diagnosis of bloodstream infections: a prospective study. Proceedings of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, (Chicago, Illinois), 2003. Abstract #D-1698.

Chatzinikolaou I, Hanna H, Graviss L, Chaiban G, Perego C, Arbuckle R, Champlin R, Darouiche R, et al. Clinical experience with minocycline and rifampin-impregnated central venous catheters in bone marrow transplantation recipients: efficacy and low risk of developing staphylococcal resistance. Infect Control Hosp Epidemiol, 24:961-965, 2003.

Bremer AA, Darouiche RO. Spinal epidural abscess presenting as intra-abdominal pathology: a case report and literature review. J Emerg Med, 26:51-56, 2004.

Darouiche RO. Treatment of infections associated with surgical implants. N Engl J Med, 350:1422-1429, 2004.

Kojic EM, Darouiche RO. Catheter-associated infections: pathogenesis affects prevention. Arch Intern Med, 164:842-850, 2004.

Raad I, Hanna H, Boktour M, Girgawy E, Danawi H, Mardani M, Kontoyiannis D, Darouiche R, et al. management of central venous catheters in patients with cancer and candidemia. Clin Infect Dis, 38:1119-1127, 2004.

Trautner BW, Darouiche RO. The role of biofilm in catheter-associated urinary tract infection. Am J Infect Contr, 32:177-183, 2004.

Trautner BW, Darouiche RO. Catheter associated infections: pathogenesis affects prevention. Arch Intern Med, 164:842-850, 2004.

Contact Information

Rabih Darouiche, M.D.
Veterans Affairs Medical Center
SCI Service (128)
2002 Holcombe Blvd.
Houston, TX 77004
Academic Office: 713-794-7128
713-794-7865 FAX

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