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Department of Pharmacology and Chemical Biology

Psychopharmacology

Master
Content

Scientists interested in psychopharmacology develop new medication uses by evaluating the effects of small molecules (synthetic compounds) and biologics (vaccines) on brain functioning and human behavior. This research includes animal studies in immunology (vaccine development and small molecule behavioral testing), and inpatient human laboratory studies and outpatient clinical trials of medications to potentially treat drug and alcohol dependence. Methodologies vary widely including assessments of cardiovascular function, recording of subjective and reinforcing effects, use of virtual reality, assessments of outpatients’ drug use by urine toxicology and self report, ratings of depression and anxiety, as well as collaborations with genetics and neuroimaging experts to elucidate genetic predictors and neural substrates of treatment response. These studies provide knowledge to inform the FDA about safety and efficacy of small molecules and biologics as potential treatments for drug use disorders (cocaine, methamphetamine, alcohol, nicotine, marijuana) as well as mood disorders (PTSD, depression).

People
First Name
Thomas
Last Name
Kosten
Honorific Title
M.D.
Jay H. Waggoner Endowed Chair
First Name
Christopher
Middle Name
D
Last Name
Verrico
Honorific Title
Ph.D.
Assistant Professor