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Pharmacology - Barth Lab

Houston, Texas

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Pharmacology - Barth Lab
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  1. Chen, K.M., Fuguo, Z., Fryszczyn, B.G., Barth, P. Naturally-evolved G protein-coupled receptors adopt metastable conformations (2012) Proc Natl Acad Sci U S A (in press)
  2. Kufareva, I. et al. Status of GPCR modeling and docking as reflected by community wide GPCR Dock 2010 assessment. (2011) Structure 19(8), 1108-26.
  3. Barth, P. Prediction of three-dimensional transmembrane helical protein structures. (2010), in Structural Bioinformatics of Membrane Proteins, Springer Editions, 231-249.
  4. Michino, M., et al. Community-wide assessment of GPCR structure modelling and ligand docking : GPCR Dock 2008 (2009) Nature Review Drug Discovery 8(6), 455-63.
  5. Barth, P.*, Zhu, J.*, Luo, B.H.*, Schonbrun, J., Baker, D., Springer, T. The structure of a receptor with two associating transmembrane domains on the cell surface : integrin aIIbb3. (2009) Molecular Cell 34(2), 234-49.
  6. Barth, P.*, Wallner, B.*, Baker, D. Prediction of membrane protein structures with complex topologies using limited constraints. (2009) Proc Natl Acad Sci U S A (Track II) 106(5), 1409-14.
  7. Barth, P., Schoeffler, A., Alber, T. Targeting metatstable coiled-coil domains by computational design (2008) Journal of the American Chemical Society, 130(36), 12038-44.
  8. Barth, P. Modulating membrane protein stability and association by design (2007) Current Opinion in Structural Biology 17(4), 460-466.
  9. Pathak, M.*, Yarov-Yarovoy, V.*, Agarwal, G., Roux, B., Barth, P., Kohout, S., Tombola, F., Isacoff , E.U. Closing in on the resting state of the shaker K+ channel (2007) Neuron 56(1), 124-140.
  10. Barth, P., Schonbrun, J., Baker D. Toward high-resolution prediction and design of transmembrane helical protein structures (2007) Proc Natl Acad Sci U S A (Track II) 104(40), 15682-15687.
  11. Barth, P., Alber, T., Harbury, P.B. Accurate, conformation-dependent predictions of solvent effects on protein ionization constants (2007) Proc Natl Acad Sci U S A (Track I) 104(12), 4898-903.
  12. Versele, M.L.A., Gullbrand, B., Shulewitz, M.J., Cid, V.J., Bahmanyar, S., Chen, R.E., Barth, P., Alber, T., Thorner J. Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae (2004) Mol Biol Cell 15, 4568-8.
  13. Barth, P., Savarin, P., Gilquin, B., Lagoutte, B., Ochsenbein, F. Solution NMR structure and backbone dynamics of the PsaE subunit of the photosystem I from Synechocystis sp. PCC 6803 (2002) Biochemistry 41, 13902-14.
  14. Barth, P.*, Guillouard, I.*, Setif, P., Lagoutte, B. Essential role of a single arginine of photosystem I in stabilizing the electron transfer complex with ferredoxin (2000) Journal of Biological Chemistry 275(10), 7030-6.
  15. Barth, P., Lagoutte, B., Setif, P. Ferredoxin Reduction by Photosystem I from Synechocystis sp. PCC 6803 : Towards an understanding of the respective roles of subunits PsaD and PsaE in ferredoxin binding (1998) Biochemistry 37, 16233-16241.

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