skip to content »

Pharmacology - Barth Lab

Houston, Texas

BCM faculty, staff and trainees are the heart of the organization.
Pharmacology - Barth Lab
not shown on screen

Barth Lab

Exploring and Reprogramming the mechanisms of signal transduction across biological membranes

GPCR activation


Our long-term goal is to understand how ligand/ membrane receptor/ downstream effector systems transmit specific signals across biological membranes and to exploit this knowledge to reengineer signaling pathways.

We address these objectives using a combination of computational and experimental approaches to model, design and reprogram ligand/ receptor/ effector interaction networks. Our long-term goal is to deconstruct the complex function and quantitatively describe the basic principles underlying these signaling networks.

We are affiliated with the Department of Pharmacology, the Verna and Marrs McLean Department of Biochemistry and Molecular Biology, the Program in Structural & Computational Biology and Molecular Biophysics, and the Duncan Cancer Center.

E-mail this page to a friend