Lynnette L. Harris, Ph.D.
Lynnette L. Harris, Ph.D.
Department of Pediatrics, Section of Psychology
Baylor College of Medicine
Lynnette L. Harris, Ph.D.
6701 Fannin St., CC1630
Clinic Phone (appointment requests): 832-822-1900
Main Office Phone: 832-822-3700
BA: Southern Illinois University at Carbondale, Carbondale IL
MA: Southern Illinois University at Carbondale, Carbondale IL
PhD: Southern Illinois University at Carbondale, Carbondale IL
Internship: Mailman Center for Child Development, University of Miami Medical School, Miami FL
Fellowship: Department of Pediatric Neurology, University of Minnesota Medical Center, Minneapolis MN
• Neuropsychological sequelae of chronic medical conditions, particularly cancer (bone marrow transplant, brain tumor, leukemia), HIV/AIDS and other immune dysfunction, and metabolic storage disease
• Neuropsychological outcomes in perinatal HIV/AIDS and in pediatric cancers, Quality of Life in chronic childhood illnesses
Current Research and Funding
• Protocol Team Member, Site PI: Memory Functioning in Children and Adolescents with Perinatal HIV Infection. Sponsored by NIH. Major goals of the project include (1) an evaluation of the presence and pattern of memory and EF deficits in HIV-infected children compared to controls and their relationship with HIV disease severity, (2) the interrelationship of change in these functions with normal development and changes in disease severity, and (3) whether memory and EF are predictive of medication nonadherence and problems with academic and adaptive functioning.
• Co-investigator, Site Neuropsychologist: Pediatric HIV/AIDS Cohort Study (PHACS). Sponsored by NIH-NICHD. Major Goals of Project are to address two critical pediatric HIV research questions: the long-term safety of fetal and infant exposure to prophylactic antiretroviral (ART) chemotherapy, and the effects of perinatally acquired HIV infection in adolescents. The goals of this network are to: (1) create a body of data to understand more full y the effect of HIV on sexual maturation, pubertal development, and socialization of perinatally HIV-infected pre-adolescents and adolescents; (2) Acquire more definitive information regarding long-term safety of antiretroviral agents when used during pregnancy and in newborns; (3) Ensure a mechanism is in place to estimate the upper bounds of risk for children associated with the use of antiretrovirals in their HIV-infected pregnant mothers as recommended in the Public Health Service Guidelines to prevent perinatal HIV transmission; and (4) Ensure that the follow-up of these populations continues.
• Co-investigator, Site Neuropsychologist: International Maternal, Pediatric, and Adolescent AIDS Clinical Trials Network (IMPAACT). Sponsored by NIH-NIAID. The mission of the IMPAACT group, which is worldwide in scope, is to significantly decrease the mortality and morbidity associated with HIV disease in pregnant women, children, and adolescents by: (1) Developing and evaluating safe and cost effective approaches for the interruption of mother-to-infant transmission; (2) Evaluating treatments for HIV-infected children, adolescents, and pregnant women, including treatment and prevention of co-infections and co-morbidities; and (3) Evaluating vaccines for the prevention of HIV sexual transmission among adolescents.
• Co-investigator, Site Neuropsychologist: Childhood Leukemia: Oxidative Stress, Cognitive Changes & Academic Outcomes. Sponsored by NIH. The long-term goal of this program of research is to increase knowledge about the mechanisms of methotrexate-induced CNS injury in order to develop interventions that will prevent or minimize tissue damage, cognitive declines and long-term academic problems that are significant challenges for long-term survivors of childhood ALL. Specific aims include (1) Describing changes in oxidative stress among children with ALL during CNS treatment with methotrexate; (2) Describing changes in cognitive abilities among children with ALL during CNS treatment with methotrexate; and (3) Describing relationships among oxidative stress, cognitive abilities, and academic outcomes among children with ALL during CNS treatment with methotrexate.
• Kamdar K, Krull K, Brouwers P, Potter B, Harris L, Holm S, Scaglia F, Etzel C, Bondy M, El-Zein R, Okcu M. (in press, Pediatric Blood & Cancer). Folate Pathway Polymorphisms Predict Deficits in Attention and Processing Speed after Childhood Leukemia Therapy.
• Chang G, Ratichek S, Recklitis C, Syrjala K, Patel S, Harris L, Rodday A, Tigiouart H, Parsons S. (in press, Pediatric Blood & Cancer). Children’s Psychological Distress During Pediatric HSCT: Parent and Child Perspectives.
• Mellins CA, Chu C, Malee K, Allison S, Smith R, Harris LL, Higgins A, Zorrilla C, Landesman S, Serchuck L, LaRussa P. Adherence to Antiretroviral Treatment Among Pregnant and Postpartum HIV-infected Women, AIDS Care, 20(8). 2008, 958-968.
• Member, International Neuropsychological Society
• Member, Baylor-UT Houston Center for AIDS Research
• Member, Houston Neuropsychological Society
• Member, Society for Pediatric Psychology
• Affiliate Member, American Academy of Clinical Neuropsychology
Awards and Honors
• Routh Student Research Award, Society for Pediatric Psychology, 1998