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Pediatrics - Neurology/

Houston, Texas

Pediatrics - Neurology and Developmental Neuroscience
Pediatrics - Neurology/
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Gary D. Clark, M.D.

Gary D. Clark, M.D.Section Chief - Neurology and Developmental Neuroscience

Professor

Contact Information:
Gary D. Clark, M.D.
6701 Fannin
Clinical Care Center, Suite 1250
Houston, TX 77030
Tel: 832-822-1750
Fax: 832-825-1717
E-mail: gclark@bcm.edu

Education

Louisiana State University Medical College - M.D.
Harvard University - Pediatric Internship and Residency
Washington University - Pediatric Research Fellowship
Washington University - Adult Neurology Residency
Washington University - Pediatric Neurology Fellowship
Washington University - Pediatric Neurology Research Fellowship

Clinical Focus

Developmental disorders, seizure disorders, learning disorders

Board Certifications

  • Pediatrics
  • Neurology
  • Special Qualification in Child Neurology

Membership in Professional Organizations

  • Society for Pediatric Research
  • American Academy of Pediatrics
  • American Academy of Neurology
  • Research Committee - Child Neurology Society
  • Investigation Workshop Committee - American Epilepsy Society

Research Interests

  • Genetic and biochemical mechanisms underlying disorders of brain development
  • Lissencephaly associated genes Lis1 (Pafah1b1), Reelin (Reln), and Doublecortin (DCX)

Selected Publications

  • Dobyns WB, Mirzaa G, Christian SL, Petras K, Roseberry J, Clark GD, Curry CJ, McDonald-McGinn D, Medne L, Zackai E, Parsons J, Zand DJ, Hisama FM, Walsh CA, Leventer RJ, Martin CL, Gajecka M, Shaffer LG. Consistent chromosome abnormalities identify novel polymicrogyria loci in 1p36.3, 2p16.1-p23.1, 4q21.21-q22.1, 6q26-q27, and 21q2. Am J Med Genet A. 2008 Jul 1;146A(13):1637-54.
  • Assadi AH, Zhang G, McNeil R, Clark GD, D'Arcangelo G. Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice. Neurosci Lett. 2008 Jul 4;439(1):100-5. Epub 2008 May 2.
  • Berg JS, Brunetti-Pierri N, Peters SU, Kang SH, Fong CT, Salamone J, Freedenberg D, Hannig VL, Prock LA, Miller DT, Raffalli P, Harris DJ, Erickson RP, Cunniff C, Clark GD, Blazo MA, Peiffer DA, Gunderson KL, Sahoo T, Patel A, Lupski JR, Beaudet AL, Cheung SW. Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region. Genet Med. 2007 Jul;9(7):427-41.
  • Zhang G, Assadi AH, McNeil RS, Beffert U, Wynshaw-Boris A, Herz J, Clark GD, D'Arcangelo G. The Pafah1b complex interacts with the Reelin receptor VLDLR. PLoS ONE. 2007 Feb 28;2(2):e252.

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