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Pediatrics - Neurology/

Houston, Texas

Pediatrics - Neurology and Developmental Neuroscience
Pediatrics - Neurology/
not shown on screen

John W. Swann, Ph.D.

John Swann, Ph.DProfessor
Scientific Director - The Gordon and Mary Cain Pediatric Neurology Research Foundation Laboratories
Co-Director - Jan and Dan Duncan Neurological Research Institute at Texas Children's

Contact Information:
John W. Swann, Ph.D.
The Cain Foundation Laboratories
The Jan and Dan Duncan Neurological Research Institute
1250 Moursund St. Suite 1225
Houston, TX 77030
Tel: 832-824-3969
Fax: 832-825-1248


Ph.D. - University of Maryland

Research Interests

  • Epileptogenesis in developing neural networks
  • Electrophysiological studies and microanatomical investigations of focal seizures in developing hippocampus
  • Long-term alterations in neural physiology and connectivity produced by early life seizures
  • Molecular mechanisms underlying the development ofchronic epilepsy

Selected Publications

  • Jacobs MP, Leblanc GG, Brooks-Kayal A, Jensen FE, Lowenstein DH, Noebels JL, Spencer DD, Swann JW. Curing epilepsy: progress and future directions. Epilepsy Behav. 2009 Mar;14(3):438-45. (PubMed)
  • Kelley MS, Jacobs MP, Lowenstein DH; NINDS Epilepsy Benchmark Stewards. The NINDS epilepsy research benchmarks. Epilepsia. 2009 Mar;50(3):579-82. (PubMed)
  • Swann JW. The spine loss paradox: clues to mechanisms and meaning. Epilepsy Curr. 2008 Nov-Dec;8(6):168-9. (PubMed)
  • Nishimura M, Owens J, Swann JW. Effects of chronic network hyperexcitability on the growth of hippocampal dendrites. Neurobiol Dis. 2008 Feb;29(2):267-77. (PubMed)
  • Lee CL, Frost JD Jr, Swann JW, Hrachovy RA. A new animal model of infantile spasms with unprovoked persistent seizures. Epilepsia. 2008 Feb;49(2):298-307. (PubMed)
  • Swann JW, Le JT, Lam TT, Owens J, Mayer AT. The impact of chronic network hyperexcitability on developing glutamatergic synapses. Eur J Neurosci. 2007 Aug;26(4):975-91. (PubMed)
  • Swann JW, Le JT, Lee CL. Recurrent seizures and the molecular maturation of hippocampal and neocortical glutamatergic synapses. Dev Neurosci. 2007;29(1-2):168-78. (PubMed)
  • Yabut O, Renfro A, Niu S, Swann JW, Marín O, D'Arcangelo G. Abnormal laminar position and dendrite development of interneurons in the reeler forebrain. Brain Res. 2007 Apr 6;1140:75-83. (PubMed)

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