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Pediatrics - Cardiology

Houston, Texas

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Pediatrics - Cardiology
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Yuxin Fan, M.D., Ph.D.

Assistant Professor, Department of Pediatrics, Section of Cardiology

Director, John Welsh Cardiovascular Diagnostic Laboratory


  • M.B., 1987 Anhui College of Traditional Chinese Medicine, Anhui, China
  • Ph.D., 1999 Fudan University, Shanghai, China
  • Fellowship, 2003-2006 University of Washington, Seattle, Wash.

Board Certifications

  • American Board of Medical Genetics

Research Interests

  • Development and implementation of diagnostic tests for acquired and genetic forms of cardiac disease
  • Screening for viruses associated with myocarditis and cardiac transplant rejection
  • Molecular diagnostic tests for genetic forms of cardiac disease including Marfan syndrome, Loeys-Dietz syndrome, familial thoracic aortic aneurysm, Barth syndrome, dilated or hypertrophic cardiomyopathy, left ventricular noncompaction, congenital heart diseases, long QT Syndrome, arrhythmia disorders and arrhythmogenic right ventricular dysplasia/cardiomyopathy
  • Investigating the underlying genetic mechanisms of dilated cardiomyopathy, Marfan syndrome, Loeys-Dietz syndrome, familial thoracic aortic aneurysm and arrhythmogenic right ventricular dysplasia/cardiomyopathy

Select Publications

  • Linardopoulou E, Williams E, Fan Y, Friedman C, Young J, Trask BJ. Human subtelomeres: hot spots of inter-chromosomal segmental duplication and gene conversion. Nature. 2005;437:94-100.
  • Palhan VB, Chen S, Peng GH, Tjernberg A, Gamper AM, Fan Y, Chait BT, La Spada AR, Roeder RG. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. PNAS. 2005;102:8472-7.
  • Fan Y, Limprasert P, Murray IVJ, Smith AC, Lee VM-Y, Trojanowski JQ, Sopher BL, La Spada AR. b-Synuclein modulates a-synuclein neurotoxicity by reducing a-synuclein protein expression. Hum Mol Genet. 2006 Oct 15;15(20):3002-11.

Contact Information

Section of Cardiology
Department of Pediatrics
Baylor College of Medicine, Feigin Center
1102 Bates Ave., Suite 430.09
Houston, TX 77030

Phone: 832-824-4155
Fax: 832-825-5159

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