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Path-Immuno - Daniel Lacorazza Lab

Houston, Texas

BCM faculty, staff and trainees are the heart of the organization.
Pathology & Immunology - Daniel Lacorazza Lab
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Publications

Sivina, M., Park, C.S., Yamada, T., Puppi, M., Coskun, S., Hirschi, K.K., and Lacorazza, H.D. Transcription factor ELF4 controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow. Arteriosclerosis, Thrombosis and Vascular Biology (2011), 31: 1185-1191.

Yamada, T., Gierach, K., Lee, P-H., Xiaohong Wang, and Lacorazza, H.D. Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target of rapamycin pathway in CD8+ T cells. Journal of Immunology (2010), 185:3824-3828.

Trancription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2. Takeshi Yamada, Chun Shik Park, Maksim Mamonkin, and Daniel Lacorazza. Nature Immunology (2009), 16(6):618:26.

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells.Lacorazza, H.D., Yamada, T., Liu, Y., Miyata, Y., Sivina, M., Nunes, J., Nimer, S.D. Cancer Cell (2006), 9:3.

Garcia-Barros, M., Lacorazza, H.D., Petrie, H., Haimovitz-Friedman, A., Cardon-Cardo, C., Nimer, S., Fuks, Z., Kolesnick, R. Host acid sphingomyelinase regulates microvascular function not tumor immunity. Cancer Res. (2004), 64(22): 8285-8291.

Lacorazza, H.D. and Nikolic-Zugic, J. Exclusion and Inclusion of TCR-alpha Proteins during T-cell Development in TCR-transgenic and normal mice. J. Immunol. (2004), 173(9): 5591-5600.

Lacorazza, H.D., and Nimer, S. The emerging role of the transcription factor MEF in hematopoiesis (review). Blood Cells, Molecules and Diseases. (2003), 31: 342-350.

Lacorazza, H.D., Miyazaki, Y., Di Cristofano, A., Deblasio, T., Hedvat, C., Cordon-Cardo, C., Mao, S., Zhang, J., Pandolfi, P.P., and Nimer, S.D. The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer Cells and NK-T Cells. Immunity. 2002, 17: 437-449.

Aifantis I, Borowski C, Gounari F, Lacorazza HD, Nikolich-Zugich J, von Boehmer H. A critical role for the cytoplasmic tail of pTalpha in T lymphocyte development. Nat Immunol. 2002, 3(5): 483-8.

Lacorazza, H.D., Porritt, H., and Nikolic-Zugic, J. Dysregulated expression of preTalpha reveals the opposite effects of pre-TCR at successive stages of T cell development. J. Immunol. 2001, 167:5689-5696.

Lacorazza, H.D., Tucek, C., Vasovic, L., Remus, K., Nikolic-Zugic, J. Premature TCRalpha-beta expression and signaling in pre-thymocytes impair thymocyte expansion and partially block their development. J. Immunol. 2001, 166:3184-3193.

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