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Path-Immuno - Daniel Lacorazza Lab

Houston, Texas

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Pathology & Immunology - Daniel Lacorazza Lab
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Sivina, M., Park, C.S., Yamada, T., Puppi, M., Coskun, S., Hirschi, K.K., and Lacorazza, H.D. Transcription factor ELF4 controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow. Arteriosclerosis, Thrombosis and Vascular Biology (2011), 31: 1185-1191.

Yamada, T., Gierach, K., Lee, P-H., Xiaohong Wang, and Lacorazza, H.D. Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target of rapamycin pathway in CD8+ T cells. Journal of Immunology (2010), 185:3824-3828.

Trancription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2. Takeshi Yamada, Chun Shik Park, Maksim Mamonkin, and Daniel Lacorazza. Nature Immunology (2009), 16(6):618:26.

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells.Lacorazza, H.D., Yamada, T., Liu, Y., Miyata, Y., Sivina, M., Nunes, J., Nimer, S.D. Cancer Cell (2006), 9:3.

Garcia-Barros, M., Lacorazza, H.D., Petrie, H., Haimovitz-Friedman, A., Cardon-Cardo, C., Nimer, S., Fuks, Z., Kolesnick, R. Host acid sphingomyelinase regulates microvascular function not tumor immunity. Cancer Res. (2004), 64(22): 8285-8291.

Lacorazza, H.D. and Nikolic-Zugic, J. Exclusion and Inclusion of TCR-alpha Proteins during T-cell Development in TCR-transgenic and normal mice. J. Immunol. (2004), 173(9): 5591-5600.

Lacorazza, H.D., and Nimer, S. The emerging role of the transcription factor MEF in hematopoiesis (review). Blood Cells, Molecules and Diseases. (2003), 31: 342-350.

Lacorazza, H.D., Miyazaki, Y., Di Cristofano, A., Deblasio, T., Hedvat, C., Cordon-Cardo, C., Mao, S., Zhang, J., Pandolfi, P.P., and Nimer, S.D. The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer Cells and NK-T Cells. Immunity. 2002, 17: 437-449.

Aifantis I, Borowski C, Gounari F, Lacorazza HD, Nikolich-Zugich J, von Boehmer H. A critical role for the cytoplasmic tail of pTalpha in T lymphocyte development. Nat Immunol. 2002, 3(5): 483-8.

Lacorazza, H.D., Porritt, H., and Nikolic-Zugic, J. Dysregulated expression of preTalpha reveals the opposite effects of pre-TCR at successive stages of T cell development. J. Immunol. 2001, 167:5689-5696.

Lacorazza, H.D., Tucek, C., Vasovic, L., Remus, K., Nikolic-Zugic, J. Premature TCRalpha-beta expression and signaling in pre-thymocytes impair thymocyte expansion and partially block their development. J. Immunol. 2001, 166:3184-3193.

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