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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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William K. Decker

Assistant Professor

Education

Ph.D. - Molecular and Human Genetics, Baylor College of Medicine, 2001

B.S. - Biology, Tuffs University, 1994

Post-Doctoral Training

Molecular and Human Genetics, Baylor College of Medicine, 2001

Cell and Gene Therapy, Baylor College of Medicine, 2001

Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, 2011

Area of Interest

Regulation of Th-1 Immunity

Current Position

Assistant Professor

Professional Positions held

Postdoctoral Fellow, Molecular and Human Genetics, Baylor College of Medicine, 2001

Postdoctoral Fellow, Cell and Gene Therapy, Baylor College of Medicine, 2001

Research Scientist, MithraGen, Inc., 2001-2004

Senior Research Scientist, Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, 2004-2011

Membership on Professional Organizations

Texans for Stem Cell Research, Austin, TX. Medical Advisory Board Member, 2010-Present

American Association for Cancer Research (AACR). Active Member, 2011-Present

Dan L. Duncan Cancer Center, Associate Member, Cell and Gene Therapy Program, 2011-Present

Representative Publications

Decker WK, Xing D, Lapushin R, Li, S, Robinson SN, Yang H, Shah N, Parmar S, Halpert, MH, Keating MJ, Gribben JG, Molldrem JJ, Shpall EJ, Wierda WG (2012) Generation of CLL-Specific Functional CTL Using CD-40-Ligated CLL APC. Submitted.

Shah N, Decker WK, Lapushin R, Xing D, Robinson, SN, Yang H, Parmar S, Tung SS, O'Brien S, Fernandez-Vina M, Shpall EJ, Wierda WG (2011) Homozygous HLS Locus and Haplotype Bias among patients with Chronic Lymphocytic Leukemia suggest a Physiologic Immune Surveillance Model of Disease Control. Leukemia 25: 1036-1039. PMID: 21350559

Decker WK, Safdar A (2011) Cytokine Adjuvants for Enhancing Vaccine Therapy of Neoplastic and Infectious Disease, Review Article. Cytokine Growth Factor Rev, 22: 177-187

Hanley P, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, Decker WK, Molldrem JJ, Liu H, Gee AP, Rooney CM, Heslop HE, Dotti G, Brenner MK, Shpall EJ, Bollard CM (2009) Functionally Active Virus-Specific T-Cells that target CMV, Adenovirus and EBV can be Expanded from Naive T-Cell Populations in Core Blood and will target a broad range of Viral Epitopes, Blood 114, 1958-1967

Steiner D, Gelovani J, Savoldo B, Robinson SN, Decker WK, Brouard N, Najjar A, Xing D, Yang H, Li S, Marini F, Zweidler-McKay PA, Bollard CM, Shpall EJ, Dotti G, Simmons PJ (2009) Noninvasive Bioluminescent Imaging Demonstrates Long-Term Multilineage Engraftment of Ex Vivo-Expanded CD34-Selected Umbilical Cord Blood Cells, Stem Cells 27, 1932-1940. PMID: 19544439

Decker WK, Xing D, Li S, Robinson SN, Yang H, Steiner D, Komanduri K, Shpall EJ (2009) Th-1 Polarization is Regulated by Dendritic Cell Comparison of MHC Class I and Class II Antigens, Blood 113, 4213-4223. PMID: 19171878

Decker WK, Safdar A (2009) Bioimmunoadjuvants for the Treatment of Neoplatics and Infectious Disease: Coley's Legacy Revisited, Cytokine Growth Factor Rev 20, 1271-1281. PMID: 19656718

Safdar A, Decker WK, Li S, Xing D, Robinson SN, Yang H, Steiner D, Rogriguez G, Shpall EJ, Bollard CM (2009) De Novo T-lymphocyte Responses Against Baculovirus-Derived Recombinant Influenzavirus Hemagglutinin generated by a naive umbilical cord model of Dendritic Cell vaccination, Vaccine 27, 1479-1484. PMID: 19185049

William Decker

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