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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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Brad D. Barrows, D.O., M.S.

Brad D. Barrows, D.O., M.S.

Chief Resident

E-mail: barrows@bcm.edu

Undergraduate Institution and Degree

University of California San Diego

Bachelors of Science in Microbiology

Graduate Institution and Degree

University of California San Diego

Masters of Science in Biology

Medical School and Degree

Touro University of Osteopathic Medicine, Vallejo, California
Doctor of Osteopathic Medicine

University of California San Francisco
Post-Sophomore Fellow in Anatomic Pathology

Professional / Research Interests

Gastrointestinal Pathology

General Surgical Pathology

Future Plans

Private Practice

Representative Publications:

Barrows, B.D., Rutkowski, M.J., Gultekm, S.H., Parsa, A.T., Tihan, T. Evidence of ambiguous differentiation and mTOR pathway dysregulation in subependymal giant cell astrocytoma. Tuck Patoloji Derg: 2012;28(2):95-103 doi:10.5146/tipath.2012.01107.

Barrows. B., Cheung, K., Bialobrzeski, T., Foster, J., Schulze, J., Miller, A. Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation. Channels. 2009 Jul; 3(4): 239-248. Cited in PubMed; PMID: 19617705.

Barrows, B.D., Griffitts, J.S., Aroian, R.V. Resistance is non-futile: resistance to Cry5B in the nematode Caenorhabditis elegans. Journal of Invertebrate Pathology. 2007 Jul; 95(3): 198-200. Cited in PubMed; PMID: 17482642.

Barrows, B.D., Haslam, S.M., Bischof, L.J., Morris, H.R., Dell, A., Aroian, R.V. Resistance to Bacillus thuringiensis toxin in Caenorhabditis elegans from loss of fucose. The Journal of Biological Chemistry. 2007 Feb; 282(5): 3302-3311. Cited in PubMed; PMID: 17135259.

Cappello, M., Bungiro, R.D., Harrison, L.M., Bischof, L.J., Griffitts, J.S., Barrows, B.D., Aroian, R.V. A purified Bacillus thuringiensis crystal protein with therapeutic activity against the hookworm parasite Ancylostoma ceylanicum. Proceedings of the National Academy of Sciences of the United States of America. 2006 Sep; 103(41): 15154-15159. Cited in PubMed; PMID: 17005719.

Barrows, B.D., Griffitts, J.S., Aroian, R.V. (2006). Caenorhabditis elegans carbohydrates in bacterial toxin resistance. In J. N. Abelson, M. I. Simon, S. P. Colowick, N. P. Kaplan, M. Fukuda (Ed.), Methods in enzymology (pp. 340-358). San Diego, CA. Elsevier inc.

Griffitts, J.S., Huffman, D.L., Whitacre, J.L., Barrows, B.D., Marroquin, L.D., Müller, R., Brown, J.R., Hennet, T., Esko, J.D., Aroian, R.V. Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions. The Journal of Biological Chemistry. 2003 Aug; 278(46): 45594-45602. Cited in PubMed; PMID: 12944392.

Major Presentations:

2013 - March. Citywide Hematology Grand Rounds. " Early T-cell Precursor Acute Lymphoblastic Leukemia", The Methodist Hospital, Houston, Texas.

2012 - December. Clinical Pathologic Conference, Baylor College of Medicine. " Here a Pain, There a Pain, and Everywhere Swollen ", Baylor College of Medicine, Houston, Texas.

2011 - June. Baylor Department of Pathlogy & Immunology Grand Rounds. " The Role of Inflammation in Carcinogenesis ", Baylor College of Medicine, Houston, Texas.

2010 - April. UCSF Departments of Pathology & Laboratory Medicine Grand Rounds. " The Role of Prostaglandin E2 in Epithelial-derived Tumors ", University of California San Francisco, San Francisco, California.

Abstracts:

Barrows, B.D., Musher, B.L., Zarrin-Khameh, N. An Unexpected Trend in the Prevalence of Microsatellite Instability in Colon Cancer. USCAP 102nd Annual Meeting. Poster 93. Abstract 605. March 2013.

Barrows, B.D., Cox, B., Gutierrez, C., Finch, C.J. Case of Thyroid - Type Carcinoma of Struma Ovarii. Cap'12 - The Pathologists' Meeting. September 2012.

Barrows, B.D., Teruya, J.. Employment of the ADAMTS13 Assay Improved the Accuracy and Efficiency of the Diagnosis and Treatment of Suspected Acquired Thrombotic Thrombocytopenic Purpura. USCAP 101st Annual Meeting. Poster 238. Abstract 1954. March 2012.

Barrows, B.D., Rutkowski, M.J., Gultekin, S.H., Parsa, A.T., Tihan, T. Immunohistochemical Assessment of Neuroepithelial Markers and Hamartin/Tuberin Expression in Subependymal Giant Cell Astrocytoma (SEGA): Further Evidence for Ambiguous Differentiation and mTOR Signal Transduction Dysregulation. USCAP 100th Annual Meeting. Poster 226. Abstract 1606. March 2011.

Barrows, B.D., Foster, T., Thakkar, P., Cheung, K., Miller, A.G. Quinidine and Cisapride Block of HERG Show Opposite Dependency on Extracellular Potassium Compared to Terfenadine and MK-499. TU-California 7th Annual Research Day

Barrows, B.D., Aroian, R.V. The mapping and identification of a gene associated with resistance to a specific crystal protein produced by Bacillus thuringiensis. West Coast Worm Meeting 244. June 2004.

Barrows, B.D., Griffits, J.S., Aroian, R.V. The bre-1 Story. International Worm Meeting 321. June 2003

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