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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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Immunology Course Descriptions

Introduction to Immunology (344-423)

This is a series of lectures stressing basic concepts in immunology. They include: development of the immune system, innate immunity, immunoglobulin structure and genetics, antigen-antibody reactions, the major histocompatibility complex and antigen presentation, T cell receptors (genetics, structure, selection), T cell activation and effector functions, anergy and apoptosis, adhesion molecules, phagocytic cell function, immune responses to infections organisms and tumors, autoimmune diseases, allergies, immune deficiencies and AIDS. Weekly reviews led by senior graduate students help to explore and clarify concepts. (Every year, term 2)
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Regulation of the Immune Response (344-325)

This course is composed of mini-lectures by faculty and student presentations and discussions of articles from the current literature. Students receive written constructive comments from the instructors to help improve their presentation content and style. The focus of the articles, selected by the participating faculty, is on the cells, proteins and mechanisms that regulate cellular and humoral immune responses. Topics that are covered include pathways for antigen presentation by MHC molecules, thymic selection, T and B cell receptor structure/function, signal transduction pathways, CD4 and CD8 cell function, apoptosis, HIV and AIDS, cell-cell interaction molecules, and B cell activation and differentiation. (Every year, term 3)
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Molecular Immunology (344-428)

This course consists of a series of organized presentations and discussions of major molecular mechanisms that regulate immune responses. Students receive written constructive comments from the instructors to help improve their presentation content and style. The course approaches the subject of immunology from the viewpoints of molecular immunology, genetics and cell adhesion molecules, cytokines, lymphocyte activation, gene regulation, signal transduction, apoptosis, immunological diseases, and immune aspects of gene therapy. Each student develops a research proposal in an area covered in the course. (Every year, term 4)
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Clinical Aspects of Immunology (344-405)

This course is designed for the first year students to learn more about the roles and importance of immunology in various human diseases and animal models, including cancer immunology, autoimmune diseases, infectious diseases, allergy and immunodeficiency diseases. The goals of this course are to introduce students to these active research topics, to bridge the basic immunology to clinical immunology, and motivate them for the selection of their own research topics related to important human diseases. This course will combine the presentation of scientific papers and reading materials in the selected topics.
(Every year, term 5)
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Introduction to Graduate Research (344-406 a,b, &c)

Introduction to Graduate Research addresses a number of issues important to making the transition into graduate studies: logical aspects of the analysis of problems and construction and testing of hypotheses; and critical reading of the literature, including an historical perspective of one's discipline, scientific scholarship and writing skills, written, graphic and public presentation. The course meets once a week over three terms. Class formats are a mixture of didactic and discussion. Specific homework assignments include preparation of oral presentations and short, weekly, writing assignments. The instructor provides written feedback on every writing assignment.

IGRa Term I The Challenge of Diversity
IGRb Term II Scientific "Method" and Writing
IRGc Term IV Grant Writing

(Every year, terms 1, 2, and 4)
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Immunology Journal Club (344-446)

This course consists of weekly meetings, attended by students and faculty, for student presentations and discussion of high impact literature in immunology. (Every year, every term)
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Directed Readings (344-458)

A course designed to cover an agreed upon subject using recent literature and one-on-one interactions via presentation of introduction, method, figures and labels, as well as the main point of the paper. (Every year, every term)
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Research Rotation (344-549)

Beginning with the first or second term of the first year, a research rotation is taken each term under the direction of individual members of the faculty. Each student will take 3-4 research rotations before deciding upon a thesis advisor. Reading and discussions of selected scientific articles with individual faculty are also available. (Every year, every term)
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Special Projects (344-435)

Students registered for Special Projects conduct research in their chosen laboratory. This course is taken after completing the first year of graduate school and before passing the qualifying exam. (Every year, every term)
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Dissertation (344-550)

Students registered for Dissertation conduct research and manuscript preparation for the doctoral degree. This course is taken after the student passes the qualifying exam. (Every year, every term)
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