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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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Stephanie A. Pangas, Ph.D.Assistant Professor


  • B.A. Kent State University, Kent, OH
  • M.S. Northwestern University, Evanston, IL
  • Ph.D. Northwestern University, Evanston, IL

Post-doctoral Training

  • Department of Pathology, Baylor College of Medicine, Houston, TX 2002-2007


  • Reproductive Biology

Area of Interest

  • Germ Cell Development

Current Position

  • Assistant Professor, Department of Pathlology, Baylor College of Medicine

Honors and Awards

  • Ruth L. Kirschstein NRSA Postdoctoral Fellowship (NIH) 2004-2007
  • Burroughs Wellcome Career Award in Biomedical Sciences 2006-2010

Professional Organization Membership

  • Society for the Study of Reproduction
  • American Association for the Advancement of Science

Representative Publications

  • Pangas, S.A ., Li X., Umans, L., Zwijsen, A., Huylebroeck, D., Gutierrez, C., Wang, D., Martin, J.F., Jamin, S.P., Behringer, R.R., Robertson, E.J., and M.M. Matzuk. (2008) Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastic tumor development in mice , Mol. Cell. Biol. , in press
  • Pangas , S.A . , Jorgez, C., Tran, M., Agno, J., Li, X., Brown, C.J., Kumar, T.R., and M.M. Matzuk (2007). Intraovarian activins are required for female fertility, Mol. Endocrinol . 21:2458-2471
  • Pangas , S.A . and M.M. Matzuk (2007). The TGF b family in the Reproductive Tract. In: TGF b , 1st Edition ( Cold Spring Harbor Press). R Derynck and K. Miyazono (Eds)
  • Pangas , S.A. , Li, X., Robertson, E.J., and M.M. Matzuk (2006). Premature luteinization and ovarian failure in ovary-specific Smad4 conditional knockout mice. Mol. Endocrinol . 20:1406-1422
  • Pangas, S.A. , Choi, Y, Ballow D., Zhao Y., Westphal H., Matzuk, M.M., and A. Rajkovic (2006) Oogenesis requires germ cell specific transcriptional regulators Sohlh1 and Lhx8 , Proc. Natl. Acad. Sci . 103:8090-8095
  • Pangas, S.A. , Yan, W., Matzuk, M.M., and A. Rajkovic (2004) Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain containing protein. Gene Expression Patterns 5:257-263
  • McKenzie, L.J., Pangas , S.A. , Carson , S.A. , Kovanci, E., Cisneros, P., Buster, J.E., and M.M. Matzuk (2004). Human granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing in vitro fertilization. Human Reproduction 19:2869-2874
  • Rajkovic, A., Pangas , S.A. , N., Ballow, D., Suzumori, N., and M.M. Matzuk (2004). NOBOX regulates oocyte-specific gene expression in early folliculogenesis. Science 305: 1157-1159
  • Pangas , S.A. , Jorgez, C.J., and M.M. Matzuk (2004) Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist, gremlin. J. Biol. Chem. 279: 32281-32286
Stephanie A. Pangas, Ph.D.

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