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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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Xin Ma, M.D., Ph.D.Assistant Professor


  • M.D.
  • Ph.D.

Departmental Affiliation

  • Pathology and Immunology

Joint Affiliations

  • Department of Family and Community Medicine, Baylot College of Medicine
  • The Methodist Hospital Research Institute, Houston, Texas
  • Katherine Hsu International Research Center of Human Infections Diseases, China

Clinical Service Area

  • Laboratory Diagnosis of Tuberculosis Infection


  • Travel and Tropical Medicine, Baylor College of Medicine

Area of Interest

  • Host and Pathogen Interaction of Human Tuberculosis Disease
  • International Health Research of Human Infectious Diseases

Representative Publications

Zhao J, Wang H, Ma X (2010) Low agreement between T-SPOT®.TB assay and tuberculin skin test among BCG-vaccinated college students in China. Int J Tuberc Lung Dis (in press)

Hu Y, Ma X, etc. (2010) A major subgroup of Beijing Family Mycobacterium tuberculosis is associated with multidrug resistance and increased transmissibility. Epidemiol Infect.2010 Apr 30:1-9. [Epub ahead of print]

Austin C, Ma X, Graviss E (2008).Common nonsynonymous polymorphisms in NOD2 gene associated with resistance/susceptibility to tuberculosis disease in African Americans.J Infect Dis 15;197:1713-6

Ma X, Liu Y, Gowen B, Graviss E, Clark A, and Musser J (2007). Toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One 2(12):e1318

Moran A, Ma X, Graviss E (2006). No evidence of association between the +874T/A single nucleotide polymorphism in the first intron of the interferon-gamma gene and human susceptibility to tuberculosis. Int J Tuberc Lung Dis 11: 113-115

Ma X, Wang H, Deng Y, Liu Z, Pan X, Musser J, Graviss E (2006). RpoB gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis in Shandong Province, China. J Clin Microbiol 44:3409-3412

Qiu L, Teeter L, Liu Z, Ma X, Musser J, and Graviss E (2006). Diagnostic associations between pleural and pulmonary tuberculosis. J Infect 53:377-386

Porsa E, Cheng L, Seale M, Delclos G, Ma X, Reich R, Musser J, Graviss E (2006). Comparison of a new ESAT-6/CFP-10 peptide-based gamma interferon assay and a tuberculin skin test for tuberculosis screening in a moderate-risk population Clin Vaccine Immunol 13:53-8

Ma X, Reich R, Wright J, Tooker H, Teeter L, Musser J, Graviss E (2003). No evidence for association between the polymorphism in the 3' untranslated region of interleukin-12B and human susceptibility to tuberculosis. J Infect Dis 188:1116-18

Ma X, Reich R, Wright J, Tooker H, Teeter L, Musser J, and Graviss E. (2003). Association between IL-8 gene and human tuberculosis susceptibility. J Infect Dis 188:349-355

Ma X, Wright J, Dou SJ, Olsen P, Teeter L, Adams G, Graviss E (2002). Ethnic divergence and linkage disequilibrium of novel SNPs in the human NLI-IF gene: evidence of human origin and lack of association with tuberculosis susceptibility. J Hum Genet 47:140-145

Ma X, Dou S, Wright J, Reich R, Teeter L, El Sahly H, Musser J and Graviss E (2001). 5'dinucleotide repeat polymorphism of NRAMP1 and susceptibility to tuberculosis among Caucasian patients in Houston, Texas. Int J Tuberc Lung Dis 6:818–823

Hemminki K, Jiang Y, Ma X, Yang K, Egevad L, Lindblad P (2002).Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: relation to dietary and other factors. Carcinogenesis 23:809-815

Smeds J, Berggren P, Ma X, Xu Z, Hemminki K and Kumar R (2002). Genetic status of cell cycle regulators in squamous cell carcinoma of the esophagus: the CDKN2A (p16INK4a and p14ARF) and p53 genes are major targets for inactivation. Carcinogenesis 23:645-655

Ma X, Yang K, Lindblad P, Egevad L, Hemminki K (2001). VHL gene alterations in renal cell carcinoma patients: novel hotspot mutations and linkage disequilibrium. Oncogene 20:5393-5400

Ma X, Jin Q, Forsi A, Hemminki K, and Kummar R (2000). Single nucleotide polymorphism analyses of the human proliferating cell nuclear antigen (PCNA) and FLAP endonuclease (FEN1) genes. Int J Cancer 88:938-942

Xin Ma, M.D., Ph.D.

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