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Pathology & Immunology

Houston, Texas

Pathology and Immunology
Pathology & Immunology
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Graduate Program Faculty & Research Interests

Research Interests and Expertise

The following is a list of some of our current research interests:

  • Cancer: mechanisms, immunotherapy, and vaccines
  • Gene therapy and genetic vaccines
  • Immune-related diseases including asthma, autoimmunity, AIDS, immunodeficiency
  • Inflammation mechanisms and disease including colitis and inflammatory bowel disease, mucosal immunity, and immune response to obesity
  • Leukocyte development, activation, and signal transduction
  • Signal transduction and transcriptional regulation
  • Mechanisms of autophagy and apoptosis
  • Hematopoietic stem cell therapies
  • Systems biology and genomics
  • Protein folding and aging
  • T32 Fellowship Support NIAID - Tse-Hua Tan, Ph.D., (PI)

Graduate Program Faculty Members

Sandeep Agarwal, M.D., Ph.D.
Assistant Professor, Department of Medicine, Section of Immunology, Allergy and Rheumatology
Scleroderma; autoimmunity and inflammation of the lungs

M. Zouhair Atassi, Ph.D.
Professor, Departments of Biochemistry and Molecular Biology, and Pathology & Immunology
Protein structure and function, and molecular and cellular immunology

John W. Belmont, M.D., Ph.D.
Professor, Departments of Molecular and Human Genetics, Pathology & Immunology, and Pediatrics
Immunogenetics, cardiovascular genetics, and the International HapMap Project

Christine Beeton, Ph.D.
Assistant Professor, Department of Molecular Physiology and Biophysics
Immunotherapy for cancer and viral infections cell differentiation

Catherine Bollard, MBChB, M.D.
Professor, Center for Cell and Gene Therapy and Departments of Pediatrics, Medicine, and Pathology & Immunology
Immunotherapy for cancer and viral infections

Min Chen, Ph.D.
Assistant Professor, Department of Pathology & Immunology
Regulation of dendritic cell function

Margaret Conner, Ph.D.
Associate Professor, Department of Molecular Virology and Microbiology and Pathology & Immunology
Pathogenesis of enteric virus infections

Richard G. Cook, Ph.D.
Professor Emeritus, Department of Pathology & Immunology
Structure and function of class I MHC molecules

Thomas A. Cooper, M.D.
Professor, Department of Pathology & Immunology
Alternative splicing in development and disease

David Corry, M.D.
Professor, Departments of Medicine and Pathology & Immunology
T cell mechanisms of disease and immune mechanisms underlying airway obstruction in a model of asthma

William Decker, Ph.D.
Assistant Professor, Department of Pathology & Immunology
Dentric cell regulation of the Th-1 response, Tumor Immunology, Cancer Vaccines

Gianpietro Dotti, M.D.
Associate Professor, Center for Cell and Gene Therapy, Departments of Medicine and Pathology & Immunology
The development of immunotherapy strategies for the treatment of B-lymphocyte derived malignancies

Dean Edwards, Ph.D.
Professor, Department of Pathology & Immunology
Steroid hormone receptors, breast cancer

N. Tony Eissa, M.D.
Professor Departments of Medicine and Pathology & Immunology
Innate immunity and inflammation

Mark L. Entman, M.D.
Professor, Departments of Medicine and Pathology & Immunology
Cardiovascular inflammation with concentration on inflammatory response following reperfusion of the infarcted myocardium

Margaret (Peggy) Goodell, Ph.D.
Professor, Departments of Pediatrics, Molecular and Human Genetics, and Pathology & Immunology
Hematopoietic stem cell biology, human hematopoietic stem cells and gene therapy, and stem cell plasticity

Stephen Gottschalk, M.D.
Associate Professor, Texas Children's Cancer Center and Department of Pathology & Immunology
Adaptive immunotherapy of T cells for malignancies

Shuhua Han, M.D.
Associate Professor, Department of Pathology & Immunology
Mechanisms of B cell development and differentiation; inflammation; Autoimmunity

Peter Hotez, M.D.
Dean, National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology and Microbiology
Vaccines targeting neglected tropical diseases

Farrah Kheradmand, M.D.
Professor, Departments of Medicine and Pathology & Immunology
Innate and adaptive immunity in human destructive lung diseases

Thomas Kosten, M.D., Ph.D.
Professor of Psychiatry, Neuroscience, Pharmacology and Immunology
Vaccines targeting addictive substances

Jake Kushner, M.D.
Associate Professor, Pediatrics-Diabetes & Endo
Type I diabetes

H. Daniel Lacorazza, Ph.D.
Associate Professor, Department Pathology & Immunology
Developmental immunology and hematopoiesis

Ann Leen, Ph.D.
Assistant Professor, Center for Cell and Gene Therapy and Departments of Pediatrics and Immunology
T Cell therapy for viral infections and cancer

Jonathan M. Levitt, Ph.D.
Assistant Professor, Departments of Urology and Pathology & Immunology
Immunotherapies and biomarkers for BPH and prostate cancer

Dongfang Liu, Ph.D.
Assistant Professor, Pediatrics-Human Immunobiology
Structure and function of the immune synapse

George Makedonas, Ph.D.
Assistant Professor, Pediatrics-Human Immunobiology
CTL Function

Dario Marchetti, Ph.D.
Professor, Department of Pathology & Immunology
Cancer invasion and metastasis

Donald M. Marcus, M.D.
Professor Emeritus, Departments of Medicine and Pathology & Immunology
Rheumatology Clinician

Graeme Mardon, Ph.D.
Professor, Departments of Pathology & Immunology, and Molecular and Human Genetics
Developmental neurobiology, retinal development

Leonid Metelitsa, M.D., Ph.D.
Associate Professor, Departments of Pediatrics and Pathology & Immunology
Biology of NK T cells and their roles in immunotherapeutic approaches against gliomas and neuroblastomas

Barry L. Myones, M.D.
Associate Professor, Departments of Pediatrics (Rheumatology) and Pathology & Immunology
Structure, expression, and function of Complement Receptors (CR)

Christina Nance, Ph.D.
Assistant Professor, Pediatrics-Immunology, Allergy & Rheumatology
HIV Therapeutics

Joel Neilson, Ph.D.
Assistant Professor, Department of Molecular Physiology and Biophysics
Post-transcriptional regulation of gene expression in immune function and cellular transformation

Jordan S. Orange, M.D., Ph.D.
Chief, Immunology, Allergy and Rheumatology, Director, Center for Human Immunobiology
Immunodeficiencies; directed secretion at the cytolytic immunological synapse; role of Nf-kB activation in cytolytic function

Frank M. Orson, M.D.
Associate Professor, Departments of Medicine and Pathology & Immunology
Genetic immunization for human diseases

Stephanie A. Pangas, Ph.D.
Assistant Professor, Department of Pathology & Immunology
Reproductive biology

Thuy L. Phung, M.D., Ph.D.
Assistant Professor, Department of Pathology & Immunology
Survival signaling pathways in vascular development and tumor angiogenesis

John R. Rodgers, Ph.D.
Associate Professor and Curriculum Committee Chair, Department of Pathology & Immunology
Evolution and function of class I MHC genes

Cliona Rooney, Ph.D.
Professor, Departments of Pediatrics (Hematology-Oncology) and Pathology & Immunology
Immunology and pathogenesis of Epstein-Barr virus, and immunotherapy for virus-associated malignancies and diseases

Roger D. Rossen, M.D.
Professor, Departments of Pathology & Immunology and Medicine
Inflammation in response to cardiac injury

William T. Shearer, M.D., Ph.D.
Professor, Departments of Pediatrics and Pathology & Immunology
Immunodeficiency

Richard N. Sifers, Ph.D.
Professor, Graduate Program Director, Department of Pathology & Immunology
Protein folding, quality control, ER stress, disease modifiers

C. Wayne Smith, M.D.
Professor, Departments of Pediatrics and Pathology & Immunology
Mechanisms of Leukocyte Accumulation in Inflammation and Tissue Injury

David M. Spencer, Ph.D.
Professor, Departments of Pathology & Immunology and Urology
Prostate cancer progression and immunotherapy, and gene therapy

Tse-Hua Tan, Ph.D.
Professor, Department of Pathology & Immunology
Signal transduction mechanisms of lymphocyte activation and apoptosis

Nikolai Timchenko, Ph.D.
Associate Professor, Department of Pathology & Immunology
Liver development and aging

James Versalovic, M.D., Ph.D.
Professor, Department of Pathology & Immunology
Microbiome, probiotics, systems biology

Jin Wang, Ph.D.
Associate Professor, Department of Pathology & Immunology
Apoptosis pathways in lymphocytes and dendritic cells

Huaizhu Wu, M.D., Ph.D.
Assistant Professor, Medicine-Athero & Lipo
T Cell responses to obesity

Qizhi (Cathy) Yao, Ph.D.
Professor, Departments of Surgery and Pathology & Immunology
Strategies for vaccine development against HIV and various types of cancer, including colorectal and pancreatic

Laising Yen, Ph.D.
Assistant Professor, Department of Pathology & Immunology
RNA-based molecular switches

Li-Yuan Yu-Lee, Ph.D.
Professor, Departments of Medicine and Pathology & Immunology
Signal transduction pathways to immune and inflammatory responses

Biao Q. Zheng, M.D., Ph.D.
Associate Professor, Department of Pathology & Immunology
Somatic genetics and development of immune responses, immunosenescence, and autoimmunity

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