Muge Kuyumcu-Martinez, Ph.D.
In the lab: January 2004 - October 2010
Funding: NRSA postdoctoral fellowship, NIH (NIAMS); American Heart Association Development Award
Current Position: Assistant Professor, University of Texas Medical Branch, Galveston
Wang, G.S., Kuyumcu-Martinez, N.M., Mathur, N., Wehrens, X.H., and Cooper, T.A. (2009) Protein kinase C inhibition ameliorates the cardiac phenotype of a mouse model for myotonic dystrophy, type 1. J. Clin. Invest. 119,3797-3806.
Kuyumcu-Martinez , N.M. , Wang, G.S., and Cooper, T.A. (2007) Increased steady state levels of CUG-BP1 in Myotonic Dystrophy 1 are due to PKC-mediated hyper-phosphorylation. Mol. Cell 28, 68-78.
Kuyumcu-Martinez NM, Cooper TA. (2006) Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy. Prog Mol Subcell Biol. 44, 133-159.
Kuyumcu-Martinez, NM ., Joachims M., and Lloyd R.E. 2002. Efficient Cleavage of Ribosome-Associated Poly(A)-binding Protein by Enterovirus 3C protease. J.Virol. 2002 Mar; 76 (5):2062-2074.
Kuyumcu - Martinez , NM ., Van Eden Marc, and Lloyd R.E.2003. Cleavage of Poly(A)-Binding Protein By Poliovirus 3C Protease Inhibits Host Cell Translation: A Novel Mechanism for Host Translation Shutoff. Mol Cell Biol. 2004 Feb; 24 (4):1779-90.
Kuyumcu - Martinez , NM ., Belliot G, Sosnovtsev SV, Green KY and Lloyd R.E.2003. Calicivirus 3C protease inhibits cellular translation by cleaving poly(A)-binding protein by enterovirus 3C protease. J Virol. 2004 Aug; 78 (15):8172-82.
Graham KL., Gustin KE., Rivera C., Kuyumcu - Martinez, NM ., Choe SS., Lloyd RE., Sarnow P., Utz PJ. Proteolytic Cleavage of The Catalytic Subunit of DNA-dependent Protein Kinase During Poliovirus Infection. J Virol. 2004. Jun 78(12):6313-21.