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Path-Immuno - Tom Cooper Lab

Houston, Texas

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Path-Immuno - Tom Cooper Lab
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Donnie Bundman

Donnie bundman Photo Research Associate
bundman@bcm.edu
713-798-5021
Joined the lab: March 2002

Publications

Orengo JP, Bundman D, Cooper, TA Biochromatic fluorescent reporter for cell-based screens of alternative splicing. Nucleic Acids Research 2006 Vol. 34(22) e148 E pub2006 Nov 16.

Ho TH, Bundman D, Armstrong DL, Cooper TA.
Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy. Hum Mol Genet. 2005 Jun 1;14(11):1539-47. Epub 2005 Apr 20.

Wang L, Lee YK, Bundman D, Han Y, Thevananther S, Kim CS, Chua SS, Wei P, Heyman RA, Karin M, Moore DD. Redundant pathways for negative feedback regulation of bile acid production. Dev Cell. 2002 Jun;2(6):721-31.

Suga Y, Jarnik M, Attar PS, Longely MA, Bundman D, Steven AC, Koch PJ and Roop DR (2000) Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, Vohwinkel syndrome and progressive symmetric erythrokeratoderma. Journal of Cell Biology 151(2) 401-412.

Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC and Roop DR (2000) Journal of Cell Biology, 151(2), 389-400.

Wojcik SM, Bundman DS and Roop DR (2000) Delayed wound healing in keratin 6a knockout mice. Molecular Cell Biology 14, 5248-5255.

DiSepio D, Bickenbach JR, Longley MA, Bundman DS, Rothnagel JA and Roop DR (1999) Characterization of loricrin regulation in vitro and in transgenic mice. Differentiation 64(4), 225-235.

Wojcik SM, Imakado S, Seki T, Longley MA, Petherbridge L, Bundman DS, Bickenbach JR, Rothnagel JA and Roop DR (1999) Expression of MK6a dominant -negaive and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle. Differentiation 65(2), 97-112.

Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR and Roop DR (1999) The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation 65(2), 119-130.

Rodriguez- Villanueva J, Greenhalgh D, Wang X-J, Bundman D, Cho S, Delehedde M, Roop D and McDonnell TJ (1998) Human keratin-1 bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene 16(7), 853-863.

Bonnekoh B, Greenhalgh DA, Bundman DS, Losai K, Chen SH, Finegold MJ, Krieg T, Woo SL and Roop DR (1996) Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma. Journal of Investigative Dermatology 106 (6), 1163-1168.

Wang X-J, Greenhalgh DA, Bickenbach JR, Jiang A, Bundman DS, Krieg T, Derynck R and Roop DR (1997) Expression of a dominant negative type II TGFß receptor in the epidermis of transgenic mice blocks TGFß - mediated growth inhibition. PNAS Volume 94, 2386-2391.

Bickenbach JR, Longley MA, Bundman DS, Dominey AM, Bowden PE, Rothnagel JA and Roop DR (1996) A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation 61, 129-139.

DiSepio D, Jones A, Longley MA, Bundman DS, Rothnagel JA and Roop DR (1995) The proximal promotor of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression. Journal of Biological Chemistry 270, 10792-10799.

Imakado S, Bickenbach JR, Bundman DS, Rothnagel JA, Attar PS, Wang X-J, Walczak VR, Wisniewski S, Pote J, Gordon JS, Heyman RA, Evans RM and Roop DR (1995) Targeting expression of a dominant negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function. Genes and Development 9, 317-329.

Bonnekoh B, Greenhalgh DA, Bundman DS, Eckardt JN, Longley MA, Chen S-H, Woo SLC and Roop DR (1995) Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo. Journal of Investigative Dermatology 104, 313-317.

Bickenbach JR, Greer JM, Bundman DS, Rothnagel JA and Roop DR (1995) Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. Journal of Investigative Dermatology 104, 430-433.

Rothnagel JA, Longley MA, Bundman DS, Naylor SL, Lalley PA, Jenkins NA, Gilbert DJ, Copelnad NG and Roop DR (1994) Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3. Genomics 23, 450-456.

Rothnagel JA, Longley MA, Holder RA, Bundman DS, Seki T, Bickenbach JR and Roop DR (1994) Genetic disorders of keratin: are alopecias a sub-set? [review] Journal of Dermatological Science 7 Supppl, S164-9.

Greenhalgh DA, Wang X-J, Rothnagel JA, Eckardt JN, Quintanilla MI, Barber JL, Bundman DS, Longley MA, Schlegel R and Roop DR (1994) Transgenic mice expressing targeted HPV -18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHA - activated papillomas. Cell Growth & Differentiation 5, 667-675.

Dominey AM, Wang X-J, King LE, Nanney LB, Gagne TA, Sellheyer K, Bundman DS, Longley MA, Rothnagel JR, Greenhalgh DA and Roop DR (1993) Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elictis hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth & Differentiation 4, 1071-1082.

Sellheyer K, Bichenbach JR, Rothnagel JA, Bundman D, Longley MA, Kreig T, Roche NS, Roberts AB and Roop DR (1993) Inhibition of skin development by overexpression of transforming growth factor ß1 in the epidermis of transgenic mice. PNAS 90, 5237-5241.

Greenhalgh DA, Rothnagel JA, Wang X-J, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA, Fisher C and Roop DR (1993) Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggests a role for fos in epidermal differentiation and neoplasia. Oncogene8, 2145-2157.

Greenhalgh DA, Rothnagel JA, Quintanilla MI, Orengo CC, Gagne TA, Bundman DS, Longley MA and Roop DR (1993) Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted V-Ha-ras oncogene. Molecular Carcinogenesis 7, 99-110.

Roop DR, Rothnagel JA, Longley MA, Bundman DS, Dominey AM and Greenhalgh DA (1992) Development of Transgenci Mouse Models of Hu;man Skin Diseases. The Biology of the Epidermis Akira Ohkawara and Joseph McGuire, eds. Elsevier Science Bublishers B.V.

Roop DR, Rothnagel JA, Greenhalgh DA, Longley MA, Bundman D, Chung S, Steinert PM, Ellis CN, Voorhees JJ, Huff CA, Yuspa SH and Rosenthal DS (1991) Modulation of epidermal differentiation by retinoids. "Retinoids: 10 years" J.H. Saurat editor

Rothnagel JA, Longley MA, Bundman D, Greenhalgh DA, Dominey AM and Roop, DR (1990) Targeting gene expression to the epidermis of transgenic mice: Potential application to genetic skin disorders. Journal of Investigative Dermatology, Volume 95:59s-61s.

Mehrel T, Hohl D, Rothnagel JA, Longley MA, Bundman D, Cheng C, Litchi U, Bisher ME, Steven AC, Steinert PM, Yuspa SH and Roop, DR (1990) Identification of a major keratinocyte cell envelope protein, loricrin. Cell 61, 1103-1112.

Timmons TM, Maresh GA, Bundman DS and Dunbar BS (1987) Use of monospecific nomoclonal and polyclonal antibodies to define distinct antigens of the porcine zonae pellucidae. Biology of Reproduction 36, 1275-1287.

Dunbar BS and Bundman DS (1987) Evidence for a role of the major glycoprotein in the structural maintenance of the porcine zona pellucida. Journal of Reproduction and Fertility 81, 363-376.

Skinner SM, Niu EM, Bundman DS, Lo C and Dunbar BS (1987) Use of immunoaffinity purified antibodies to zona pellucida to compare alloimmunization of male and female rabbits. Journal of Reproductive Immunology 12, 81-92.

Dunbar BS, Dudkiewicz AB and Bundman DS (1985) Proeolysis of specific porcine zona pellucida glycoproteins by boar acrosin. Biology of Reproduction 32, 619-630.

Dunbar BS, Smika DE, Bundman DS and Dunbar BD (1985) Identification of cultivar-specific proteins of winter wheat (T. aestiuium L.) by high-resolution two-dimentional polyacrylamide gel electrophoresis and color-based silver stain. Electrophoresis 6,39-43.

Dunbar BS, Bundman DS and Dunbar BD (1983) A rapid laboratory method for developing contact prints of stained polyacrylamide gels. Electrophoresis4, 258-259.

Wolgemuth DJ, Celenza J, Bundman DS and Dunbar BS (1984) Formation of the rabbit zona pellucida and its relationship to ovarian follicular development. Developmental Biology 106, 1-14.

Drell DW, Wood DM, Bundman D and Dunbar BS (1984) Immunological comparison of antibodies to porcine zonae pellucidae in rats and rabbits. Biology of Reproduction 30, 435-444

Peterson RN, Russell LD, Hunt W, Bundman D and Freund M (1983) Characterization of boar sperm plasma membranes by two-dimensional PAGE and isolation of specific groups of polypeptides by anion exchange chromatography and lectin affinity chromatography. The Journal of Andrology 4, 71-81.

Peterson RN, Russell LD, Bundman DS, Conway M and Freund M (1981b) The interaction of living boar sperm and sperm plasma membranes with porcine zona pellucida. Developmental Biology 84, 144-156.

Peterson RN, Russell LD, Spaulding G, Bundman DS, Buchanan J and Freund M (1981a) Electrophoretic and chromatographic properties of boar sperm plasma membranes: Antigens and polypeptides with affinity for isolated zonae pellucidae. The Journal of Andrology 2, 300-311.

Peterson RN, Russell L, Bundman D and Freund M (1980) Evaluation of the purity of boar sperm plasma membranes prepared by nitrogen cavitation. Biology of Reproduction 23, 637-645.

Peterson RN, Russell L, Bundman D and Freund M (1980) Sperm-egg interactions: Direct evidence for boar sperm plasma membrane receptors for porcine zoan pellucida. Science, Volume 207, 73-74.

Peterson RN, Russell L, Bundman D, and Freund M (1979) Calcium binding to plasma membrane vesicles of boar spermatozoa. Biology of Reproduction 21, 538-588.

Peterosn RN, Russell L, Hook L, Bundman D and Freund M (1980) Characterization and localization of adenylyl cyclase in membrane vesicles and intact boar and human spermatozoa. The Journal of Cell Science 43, 93-102.

Peterson RN, Seyler D, Bundman D and Freund M (1979) The effect of theophyllin and dibutyryl cyclic AMP on the uptake of radioactive calcium and phosphate ions by boar and human spermatozoa. Journal of Reproduction and Fertility 55, 385-390.

Peterson RN, Russell L, Bundman D and Freund M (1978) Presence of microfilaments and tubular structures in boar spermatozoa after chemically inducing the acrosome reaction. Biology of Reproduction 19, 459-466.

Peterson RN, Bundman D and Freund M (1978) Use of a fluorescent dye to measure drug-induced changes in the membrane potential of boar spermatozoa. Life Sciences, Volume 22, 659-666.

Peterson RN, Bundman D and Freund M (1977) Binding of cytochalasin B to hexose transport sites on human spermatozoa and inhibition of binding by purines. Biology of Reproduction 17,198-206.

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